GRAS is a recently discovered family of plant-specific proteins that play important regulatory roles in diverse aspects of plant development. Several of the motifs present in the GRAS proteins suggest that they function as transcription factors, although homology-searching programs have revealed no significant similarity to any non-plant proteins. Here we propose that the GRAS proteins are related to the Signal Transducers and Activators of Transcription (STAT) family of proteins. STATs are known in many non-plant species, and act as intracellular intermediaries (...) between extracellular ligands and the transcription and activation of genes. Our hypothesis is that the GRAS proteins perform this function in plants, with mechanisms similar to those of the animal STATs. If true, this hypothesis has important implications for the evolution of phosphotyrosine based signal transduction systems in eukaryotic organisms. BioEssays 22:573–577, 2000. © 2000 John Wiley & Sons, Inc. (shrink)

In the course of an immune response, antibodies undergo affinity maturation in order to increase their efficiency in neutralizing foreign invaders. Affinity maturation occurs by the introduction of multiple point mutations in the variable region gene that encodes the antigen binding site. This somatic hypermutation is restricted to immunoglobulin genes and occurs at very high rates. The precise molecular basis of this process remains obscure. However, recent studies using a variety of in vivo and in vitro systems have revealed important (...) regulatory regions, base motifs that are preferred targets of mutation and evidence that transcription may play an active role in hypermutation. BioEssays 20:227–234, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

The isolation requirements of the coronavirus epidemic and the intuitive display advantages of live-streaming have led to an increasing number of retailers shifting to social live-streaming platforms and e-commerce live-streaming platforms to promote and sell their products in real time. However, the provision of live-streaming services will also incur high live-streaming effort costs. In this paper, we develop two decision models for retailers to sell goods through a single online shop and both online shop and live-streaming room; we also present (...) the optimal decisions of pricing and live-streaming efforts. Furthermore, we identify the profitability conditions for retailers to determine when to provide live-streaming services. In addition, we examine the impact of the provision of live-streaming services on the optimal price and live-streaming effort. We obtain three findings. First, there is a unique optimal decision on the price and live-streaming effort under certain conditions. Second, when the effect coefficient of the live-streaming room reaches a certain threshold, there are enough customers who enter the live-streaming room to watch and buy and it is profitable for retailers to provide live-streaming service. Finally, the optimal price and live-streaming effort increase with the increase in average return loss, the effect coefficient of live-streaming effort, and the extra return rate and decrease with the increase in the proportion of customers who choose to buy in the online shop and the price discount coefficient in the live-streaming room. (shrink)

The aim of this paper is to describe and analyze people's confidence in political institutions in the so-called BRICS countries, that is, Brazil, Russia, India, China, and South Africa. I argue that the quality of macroeconomic indicators cannot explain the variation in political confidence between the five most dynamic new emerging economies, and that there is no substantial difference among the young, middle-aged, and senior-aged groups. By combing data from the Asia Barometer Survey and the World Value Survey, I provide (...) two complementary approaches, one sociocultural and the other micropolitical, to reveal the factors that influence people's confidence in four major political institutions. The explanatory effects of these two approaches are mixed. Political identity and values, in most cases, have a significant impact on political confidence. On the other hand, high levels of interpersonal social trust, individual happiness, and satisfaction with living standards also show positive influences. (shrink)

Dujiangyan irrigation system of more than 2000 years history is a symbol of originality of Chinese ancestors both in its conception and project mode. It is still working well and benefit Chengdu Plain nowadays while other comparable water conservancy projects of the same or later age have vanished and been forgotten. More than just a world-famous cultural heritage, it shows the harmonious relationship between man and nature. And it also reveals us how to solve problems in the era of economic (...) globalization, such as the constantly silt up of the dams, the exhaustion of the energy and the crisis of the deterioration of ecosystem. The inspirations it gives us range from technology to humanities, from economy to various aspects in social life. In a word, Dujiangyan irrigation system demonstrates the wisdom and creativity of Chinese people and has a universal significance despite the change of time and space. (shrink)

Journal of Mathematical Logic, Volume 24, Issue 03, December 2024. We construct a model in which MA[math] holds and [math] fails. This shows that MA[math] does not imply [math] and answers an old question of Larson and Todorcevic in [Katetov’s problem, Trans. Amer. Math. Soc. 354(5) (2002) 1783–1791]. We also investigate different strong colorings in models of MA[math].

The purpose of this study is to extend prior research on this topic by investigating whether the impact of ownership concentration moderates the link between corporate social performance and financial performance. This study uses a set of unique, hand-collected pollution control data to measure CSP, based on a sample of Taiwanese listed companies during the period from 1996 to 2006. The results of the empirical analysis provide firm support for the idea that the divergence between control rights and the cash (...) flow rights of controlling owners negatively moderates the link between social and short- and long-run FP. (shrink)

This study aims to explore if local responsiveness pressure and subsidiary resources influence green management adoption of overseas subsidiaries, and to investigate the relationships between the level of green management adoption and performance. The 101 effective samples were collected from 583 Taiwanese firms, which are listed in the top 1000 manufactory firms and have invested in China. Though structural equation model analysis' empirical results indicate that local responsiveness pressure and subsidiary resources both have positive effects on the level of green (...) management adoption of the subsidiary. This study also suggests that the level of green management adoption is positively related to the subsidiary's performance. (shrink)

Language teacher research is conducive to the development of teachers’ teaching skills and professional careers. Thus, many English teacher education programs require student teachers to do research. However, some empirical findings suggest that English as a foreign language student teachers lack research motivation. Consequently, finding suitable interventions to increase their research motivation has become increasingly necessary. In light of the importance of research motivation intervention, this study involved designing an experiment to identify the effect of a value and interest intervention (...) including the sharing of positive research experiences to improve student teachers’ research motivation. Quantitative questionnaires and qualitative semi-structured interviews were used to gather evidence on the change in student teachers’ research motivation during the intervention. The interview data revealed that student teachers’ research motivation was influenced by their belief in the value of research to their teaching practice. The experiment results suggested that student teachers’ intrinsic and extrinsic research motivations both increased after the intervention. However, the intervention was not effective in curbing their failure avoidance tendency. Pedagogical implications of the results are discussed at the end of this article. (shrink)

Under the influence of the linguistic turn in philosophy, contemporary Western philosophers typically limit their thinking on pluralism to the realm of language. This sort of pluralism can be named as pluralism of significance. I propose another version of pluralism in light of Confucianism, which extends the concerns from the realm of language to the realm of experience – I call it pluralism of presence. In this article, I first expound the aforementioned two versions of pluralism on the basis of (...) Hans-Georg Moeller’s semiotic trichotomy. I then argue that the conflict between multiculturalism and cultural identity in today’s globalized world and the failure of pluralism of significance in resolving this conflict can be overcome by pluralism of presence. Finally, I show a possibility of reconciliation between pluralism of significance and pluralism of presence. (shrink)

The relationships between age and the life-supporting treatments use, and between gender and the life-supporting treatments use are still controversial. Using extracorporeal membrane oxygenation as an example of life-supporting treatments, the objectives of this study were: to examine the relationship between age and the extracorporeal membrane oxygenation use; to examine the relationship between age and the extracorporeal membrane oxygenation use; and to deliberate the ethical and societal implications of age and gender disparities in the initiation of extracorporeal membrane oxygenation. This (...) is a population-based, retrospective cohort study. Taiwan’s extracorporeal membrane oxygenation cases from 2000 to 2010 were collected. The annual incidence rate of extracorporeal membrane oxygenation use adjusting for both age and gender distribution for each year from 2000 to 2010 was derived using the population of 2000 as the reference population. The trend of extracorporeal membrane oxygenation use was examined using time-series linear regression analysis. We conducted joinpoint regression for estimating the trend change of extracorporeal membrane oxygenation use. The trends of extracorporeal membrane oxygenation use both for different gender groups, and for different age groups have been significantly increasing over time. Men were more likely to be supported by extracorporeal membrane oxygenation than women. Women’s perspectives toward life and death, and women’s perception of well-being may be associated with the phenomenon. In addition, the patients at the age of 65 or older were more likely to be supported by extracorporeal membrane oxygenation than those younger than 65. Family autonomy/family-determination, and the Confucian tradition of filial piety and respecting elders may account for this phenomenon. This study showed gender and age disparities in the initiation of extracorporeal membrane oxygenation use in Taiwan, which may be accounted for by the cultural and societal values in Taiwan. For a healthcare professional who deals with patients’/family members’ medical decision-making to initiate life-supporting treatments, he/she should be sensitive not only to the legality, but also the societal and ethical issues involved. (shrink)

The topic of this issue of Contemporary Chinese Thought is the authorship, annotations, and philosophical interpretation of the Wuxing and evidence of the thought of Zisi and Mencius in the Wuxing. Four of the essays translated here are by Chen Lai, formerly professor of Chinese philosophy at Peking University and now dean of the School of Traditional Chinese Learning at Tsinghua University. An essay by Xing Wen, of Dartmouth College, provides context for a proper understanding of the Wuxing and Chen (...) Lai's scholarship on the Wuxing. (shrink)

A result from a standard linear model course is that the variance of the ordinary least squares (OLS) coefficient of a variable will never decrease when including additional covariates into the regression. The variance inflation factor (VIF) measures the increase of the variance. Another result from a standard linear model or experimental design course is that including additional covariates in a linear model of the outcome on the treatment indicator will never increase the variance of the OLS coefficient of the (...) treatment at least asymptotically. This technique is called the analysis of covariance (ANCOVA), which is often used to improve the efficiency of treatment effect estimation. So we have two paradoxical results: adding covariates never decreases the variance in the first result but never increases the variance in the second result. In fact, these two results are derived under different assumptions. More precisely, the VIF result conditions on the treatment indicators but the ANCOVA result averages over them. Comparing the estimators with and without adjusting for additional covariates in a completely randomized experiment, I show that the former has smaller variance averaging over the treatment indicators, and the latter has smaller variance at the cost of a larger bias conditioning on the treatment indicators. Therefore, there is no real paradox. (shrink)

It has been found in many cases that consumers are prone to exhibit impulsive buying behavior that is manifested as being immediate, emotional, and irresponsible especially under short video scenario. Supported by the customer inspiration theory, this study explores the psychological mechanism underlying impulse purchase in short videos that differentiates the traditional web shopping by the strong sense of presence in short video marketing. On the basis of a questionnaire survey and three laboratory experiments, this study examines the relationship among (...) presence, customer inspiration, and impulse purchase intention. The empirical results point to the fact that social presence, co-presence, and physical presence have significant positive effects on impulse purchase intention, and customer inspiration mediates the effect of social presence, physical presence, and co-presence on impulse purchase intention. Furthermore, it is indicated that social and co-presence have stronger influences on impulse purchase intention than physical presence, thus proving a stronger effect of social factors on impulse purchase intention than physical factors in short video environment. The research results testify the impact of presence on consumer behavior in the upgrading short video marketing and provide valuable reference for marketing strategies to shorten consumers' decision-making time in short video purchase. (shrink)

Abstract:The most important themes of Wang Lü's painting theory are the "true self" and the "true thing." One reason this topic has not received sufficient attention is that the original text was altered. This article aims to correct and reinterpret the text. After textual research and interpretation, Wang Lü's paintings and painting theory have been reevaluated. This article also responds to some difficult topics such as the relationship between "form" (ᔶ) and "meaning" (ᛣ) and between "following" (ᕲ) and "not following" (...) (䘩) the rules in Chinese painting theory. (shrink)

全书以灾异思想为切入点，以西汉经学灾异思想与思潮为中心，结合先秦至西汉间的时代背景与思想氛围，在细致考察与解读相关文本的基础上，对西汉经学灾异思想的观念来源与理论先导、创立过程与时代特色、理论形态与建 构方法，以及灾异思潮与现实政治的互动等问题，进行了全面深入的研究和探讨；对于经学灾异思想何以会在西汉建立、经学灾异思潮缘何会在西汉爆发、经学灾异论造成了怎样的历史影响，以及如何评价灾异论氛围中的西汉儒 学与儒生群体等问题，本书也进行了系统的反思，并提出了一系列见解。.

This study aimed to explore the mediating effects of internet gaming disorder, social network use, and generalized pathological internet use on the association between loneliness and depression. A total of 2211 junior high school students completed questionnaires regarding loneliness, internet gaming disorder, social network use, GPIU, and depression. The results of a structural equation model revealed that the path coefficient of loneliness to depression was significantly positive, loneliness could not predict depression through GPIU directly, but loneliness could predict depression through (...) internet gaming disorder to GPIU, loneliness could predict depression through social network use to GPIU, and loneliness could not predict depression through internet gaming disorder to social network use to GPIU. These results provided significant implications for the prevention and reduction of depression in Chinese junior high school students. (shrink)

Social anxiety and stress type can influence strong conformity among adolescents; however, the interaction between them is not clear. In this study, 152 adolescents were recruited and assigned one of two conditions: an interaction and a judgment condition. In the interaction condition, adolescents with high social anxiety (HSA) were less likely to conform when completing a modified Asch task, compared to adolescents who had low social anxiety. In the judgment condition, adolescents with HSA were more likely to conform to the (...) opinions from the unanimous majority. The results suggest that adolescents with HSA may show different styles of strong conformity with the change of stress type. We believe that socially anxious adolescents avoid potential social situations with weaker conformity, while avoiding negative evaluations from others with stronger conformity. These findings contribute to a better understanding of the social dysfunctions among adolescents with HSA and provide a new direction for clinical interventions. (shrink)

Xunzi’s philosophy of language was mainly unfolded through the discrimination of ming 名 (names) and shi 实 (realities) and the discrimination of yan 言 (words) and yi 意 (meanings). Particularly, the discrimination of names and realities was centered on the propositions that realities are realized when their names are heard and that names are given to point up realities, including the view on the essence of language such as names expect to indicate realities and conventions established by usage, the view (...) of development of language such as coming form the former usage and being newly established, and the view of functions of language such as discriminating superiority and inferiority and differentiating identities and differences ; while the discrimination of words and meanings mainly contained two aspects: One was that words could completely represent meanings while it could not do so on the other hand, and the other was that the Dao should be grasped through an unoccupied, concentrated and quiet mind. Xunzi’s philosophy of language stressed both language’s value attribute and its cognitive attribute, and it is the greatest achievement of pre-Qin dynasty’s philosophy of language. (shrink)

本书是一本研究建筑学的书籍, 全书包括有《现象学与建筑学的思考》、《建筑中的神性》等多篇文章.

Whether risk events can be effectively controlled and mitigated is largely influenced by people’s perceptions of risk events and their behavioral cooperation. Therefore, this study used a web-based questionnaire to investigate the specific factors influencing people’s risk perceptions and behaviors, and included a test for the difference in the effect of positive and negative emotions of the audiences. The results show that the overall model has good explanatory power for the behavioral variables, and how people’s use of different media significantly (...) influenced their positive and negative emotions; how people’s frequency of TV use significantly influenced their risk susceptibility and how online media use significantly influenced their risk severity ; how people’s sense of efficacy for risky events is the strongest predictor of their risk control behavior; and that there are different mediating effects of different emotions and risk severity and sense of efficacy between the frequency of media use and risk control behavior. (shrink)

The Party school has always been an important bastion through which our Party trains and educates its cadres in Marxism-Leninism and Mao Zedong Thought. The Party Central Committee headed by Chairman Hua has laid great emphasis on the Party school since the smashing of the "gang of four" and has made special decisions on how successfully to run the Party schools on different levels. Chairman Hua and Vice Chairman Ye personally made important speeches at the opening ceremony of the Central (...) Party School and indicated the direction in which the Party school should be run during the new stage of historical development. Pursuant to the Central Committee's decision, the Shanghai Municipal Party Committee has restored its Party school which had been closed down for some ten years by the "gang of four." Since its reopening, the Municipal Party School has already run a one-term study class for the cadres and has achieved fairly good results. In the future, we will run the study class every term and strive to run the Party school better and better. (shrink)

A study of the abnormal sex ratio at birth in China reveals that it is not an entirely new phenomenon that emerged since the 1980s, but is simply more visible at present. Deliberate intervention to determine the sex of children has existed in the past few decades, at least in certain groups. Apart from modern medical methods, traditional Chinese medical practice is shown to be highly accurate in identifying the sex of a fetus. This may lead to sex-selective abortion and (...) an abnormal sex ratio at birth. The possible causes of the abnormal sex ratio at birth include not only the real imbalance due to the disturbance of social factors, but also a spurious one attributable to the under-counting of female births. The real magnitude of the imbalance has been exaggerated by statistical error. The phenomenon is a complicated one reflecting the comprehensive socioeconomic setting. Among these factors, the stage of the fertility transition is one of the most decisive. (shrink)

Der Autor hat sich die Aufgabe gestellt, Husserls Phänomemologie der Zeit systematisch zu interpretieren und das Differenzieren und Identifizieren zu problematisieren. Er untersucht Husserls Zeitphänomenologie mit rein phänomenologischem Blick, damit folgende Fragen beantwortet werden können: Worin liegt die Bedeutung von Husserls Zeitforschung? Beschränken sich seine Zeitgedanken noch auf die Denkweise der Metaphysik, wie Natorp und Heidegger behaupten. Wenn ja, worin verkörpert sich die metaphysische Denkweise und inwiefern bewegen sie sich im Rahmen der Tradition? Diese Untersuchung beginnt damit, Husserls Zeitphänomenologie systematisch (...) zu rekonstruieren, weil sich Husserls Gedanken und Forschungen zur Zeit uber zahlreiche Manuskripte und Werke verteilen. Nur anhand einer umfassenden, systematischen Rekonstruktion der Zeittheorie Husserls können die obigen Fragen angemessen beantwortet werden. Der Autor geht dann auf die Differenz- und Identitätsprobleme in Husserls Zeitphänomenologie ein. Er versucht Aporien, wie den unendlichen Regress, zu analysieren und zu beantworten. (shrink)