Students of Thomas Aquinas have so far lacked a comprehensive study of his doctrine of the transcendentals. This volume fills this lacuna, showing the fundamental character of the notions of being, one, true and good for his thought. The book inquires into the beginnings of the doctrine in the thirteenth century and explains the relation of the transcendental way of thought to Aquinas's conception of metaphysics. It analyzes 'Being', 'One', 'True', 'Good' and 'Beautiful' individually and discusses their importance for the (...) philosophical knowledge of God. Medieval Philosophy and the Transcendentals: The Case of Thomas Aquinas is intended as a contribution to the question 'What is philosophy in the Middle Ages?' It argues that the doctrine of the transcendentals is essential for understanding medieval philosophy. (shrink)

Mathematical models are an important tool in the development ofsoftware technology, including programming languages and algorithms.During the last few years, a new class of such models has beendeveloped based on the notion of a mathematical game that isespecially well-suited to address the interactions between thecomponents of a system. This paper gives an introduction to thesegame-semantical models of programming languages, concentrating onmotivating the basic intuitions and putting them into context.

Cancers often express hundreds of genes otherwise specific to germ cells, the germline/cancer (GC) genes. Here, we present and discuss the hypothesis that activation of a “germline program” promotes cancer cell malignancy. We do so by proposing four hallmark processes of the germline: meiosis, epigenetic plasticity, migration, and metabolic plasticity. Together, these hallmarks enable replicative immortality of germ cells as well as cancer cells. Especially meiotic genes are frequently expressed in cancer, implying that genes unique to meiosis may play a (...) role in oncogenesis. Because GC genes are not expressed in healthy somatic tissues, they form an appealing source of specific treatment targets with limited side effects besides infertility. Although it is still unclear why germ cell specific genes are so abundantly expressed in cancer, from our hypothesis it follows that the germline's reproductive program is intrinsic to cancer development. (shrink)

After 1945, Czech philosophy and culture were first introduced to existentialism. First it was the original works of French existentialists (Sartre, Camus, Marcel), later by means of the journal Letters (1947) and Václav Černý (The first book on existentialism, 1948). The acceptance of existentialism in Czech context was not univocal. Besides factual analyses (J. Patočka, V. Navrátil, V. T. Miškovská), existentialism met with criticism and rejection mainly from Marxists and Catholic scholars for its rational weakness, pessimism, helplessness and intellectual decline.

We prove the NTP1 property of a geometric theory T is inherited by theories of lovely pairs and H‐structures associated to T. We also provide a class of examples of nonsimple geometric NTP1 theories.

The paper presents the sources and the development of the medieval doctrine of transcendentals. In Aertsen's opinion transcendental philosophy of the Middle Ages differs considerably from the ontological doctrine of the Ancients as well as from the modern theory referring to the sphere of cognition. The beginnings of the medieval doctrine of the transcendentals were inspired mostly by considerations concerning primary conceptions of human mind included in Avicenna's "Metaphysica". Furthermore, they were connected with the Aristotelian idea of science, the Boethian (...) axiomatic method of "common conceptions of the soul", and theologians' interest in the horizon of human intellectual knowledge. Beside the Aristotelian-Avicennian reduction to the most universal predicate Albert the Great acknowledge another reduction (originating from the Christian-Neoplatonic tradition): reduction to the first cause. In his opinion, these two resolutions are complementary to each other. In the philosophy of Thomas Aquinas, transcendentals are most fundamental insofar as they are the foundations of theoretical and practical science. The principle of contradiction – considered as the beginning of theoretical science – rests on the understanding of "being", and the first precept of natural law is founded on "the good". The development of the doctrine of the transcendentals in 13th century aloows to call the period "the second beginning of metaphysics" – since it changes the understanding of the proper subject of First Philosophy. In Albert the Great, for example, matephysics ceases to be the science of the divine, and becomes the science concerning what is first and the most fundamental – "being-as-being". In St. Bonaventure's philosophy, the doctrine of the transcendentals undergoes a theologizing transformation: that, which is first in the cognitive order is, at the same time, first ontologically. For Bonaventure, the latter "first" is God. (shrink)

Winnicotts Konzept des »Holding« bezieht sich auf das komplexe psychische Tun und Wirken der Mutter für ihr neugeborenes Kind, also darauf, dass sie sowohl als »Umwelt-Mutter« als auch als »Objekt-Mutter« fungieren muss. Während das Holding mit der Umwelt-Mutter assoziiert ist, möchte ich das »Containing« hier der Objekt-Mutter zuordnen. Es soll gezeigt werden, dass Winnicott diese Konzepte in Anlehnung an Freuds frühe Beobachtungen der für die emotionale Entwicklung des Kindes entscheidenden Rolle der Mutter erarbeitete. Obwohl die Rolle des Vaters ebenso wichtig (...) sei, betonte Winnicott, es liege in der Hand der Mutter, der Psyche des Kindes die Bedeutung des Vaters nahezubringen – oder nicht. Anknüpfend an Winnicotts späte Formulierungen aus »Objektverwendung und Identifizierung« wird vorgeschlagen, dass das psychische Überleben des Objekts die entscheidende interpsychische Dynamik im Kern der Eltern-Kind-Beziehung ist. Das intrapsychisch entstehende subjektiv überlebende Objekt gewinnt im Kontext der analytischen Situation potenziell an Stärke, wenn der Analytiker imstande ist, sein Überleben zu unterstützen. Um diese Themen kreist Winnicotts Objektbeziehungstheorie. (shrink)

The focus of this article is on an ambivalent conception in medieval thought, namely the term ‘transcendens’, which on the one hand signifies a reality beyond created beings, i.e. God, and on the other hand signifies something common to all beings. Armandus de Bellovisu, in his Declaratio difficilium terminorum, has thematized exactly this difference between transcendence that follows from ‘nobility of being’ and that which follows from ‘commonness of predication’ . The medieval term ‘transcendens’, because of its ambiguity, thus includes (...) two fundamental concepts, which represent divergent philosophical tendencies concerning the specification of First Philosophy: the one understands it as «Philosophy of Transcendence», the other as «Transcendental Philosophy». The history of metaphysics is characterized by the tension between these two tendencies, but as we shall see, it also shows that they are intimately connected. (shrink)

The main thesis of this monograph, and its novelty, is the attempt to read Newman's work not only as a defence of the author's life, but as a defence of individual life in general. This reading is done against the background of his profound personalism based on two foundations: truth and responsibility.

Tato práce se zabývá možnými přístupy k etice sexuality, jejich klady i zápory. Etikou sexuality zde není míněno moralizování, stejně tak sexualitou není míněn pouze koitus, pohlavní chování je zde míněno v širším významu tedy včetně rozlehlé oblasti lidského svádění, okolků či otálení. Popsány jsou čtyři klasické přístupy k etice sexuality: tradicionalistický, romantický, marxisticko-feministický a liberální, avšak uvážen je i přístup antinatalistický, který vyplývá z asymetrického argumentu Davida Benatara uveřejněného v jeho práci Nebýt či být. Benatarův antinatalizmus totiž vytváří etiku (...) pohlavního chování, v níž pouze sex, který nevede k rozmnožení, může být morální. I když je tento pátý, antinatalistický přístup značně kontroverzní a zdaleka ne intuitivní, extrémnost jeho pozic se příliš neliší od tradicionalistického pohledu, v němž je morální pouze sex k rozmnožení vedoucí, tyto dva přístupy tak lze postavit do přímé opozice jako dvě krajní možnosti uvažování o etice pohlavního chování. Roli střední cesty v takovém řazení potom zaujme liberální přístup, který jako jediný etiku sexuality nevidí jako etiku odlišnou od jiných lidských činností. (shrink)