As genomic research becomes commonplace across the world, there is an increased need to coordinate practices among researchers, especially with regard to data sharing. One such way is an international code of conduct. In September 2020, an expert panel consisting of representatives from various fields convened to discuss a draft proposal formed via a synthesis of existing professional codes and other recommendations. This article presents an overview and analysis of the main issues related to international genomic research that were discussed (...) by the expert panel, and the results of the discussion and follow up responses by the experts. As a result, the article presents as an annex a proposal for an international code of conduct for data sharing in genomics that is meant to establish best practices. (shrink)

Biobanks act as the custodians for the access to and responsible use of human biological samples and related data that have been generously donated by individuals to serve the public interest and scientific advances in the health research realm. Risk assessment has become a daily practice for biobanks and has been discussed from different perspectives. This paper aims to provide a literature review on risk assessment in order to put together a comprehensive typology of diverse risks biobanks could potentially face. (...) Methodologically set as a typology, the conceptual approach used in this paper is based on the interdisciplinary analysis of scientific literature, the relevant ethical and legal instruments and practices in biobanking to identify how risks are assessed, considered and mitigated. Through an interdisciplinary mapping exercise, we have produced a typology of potential risks in biobanking, taking into consideration the perspectives of different stakeholders, such as institutional actors and publics, including participants and representative organizations. With this approach, we have identified the following risk types: economic, infrastructural, institutional, research community risks and participant’s risks. The paper concludes by highlighting the necessity of an adaptive risk governance as an integral part of good governance in biobanking. In this regard, it contributes to sustainability in biobanking by assisting in the design of relevant risk management practices, where they are not already in place or require an update. The typology is intended to be useful from the early stages of establishing such a complex and multileveled biomedical infrastructure as well as to provide a catalogue of risks for improving the risk management practices already in place. (shrink)

David Gauthier is one of the most outstanding and influential philosophers working in moral theory today, and his book Morals by Agreement has established him as a preeminent defender of contractarian moral theory. This volume brings together a selection of his best essays on contractarianism, many of which have become difficult to find.

Des millions d'années avant l'apparition de l'homme, la vie avait déjà inventé la roue, le moteur atomique, le sonar, le vol stationnaire, la capture de l'énergie solaire, l'éclairage électrique, le GPS et des myriades de techniques qui nous dépassent encore complètement : cicatrisation, reproduction, congélation suivie de réanimation, et des cerveaux dont chacun des milliards de neurones est un univers informatique. Pour le comprendre, il a fallu attendre que nos propres technologies atteignent les profondeurs moléculaires du vivant, nous révélant que (...) les inventions de la nature étaient infiniment plus complexes que les nôtres. " Le service Recherche et Développement de la nature a 3,8 milliards d'années d'avance sur ceux de nos entreprises ", aime dire Janine Benyus, la naturaliste américaine qui a inventé le concept de biomimétisme. " Il s'agit de nous en inspirer pour pousser plus loin nos propres inventions, mais surtout pour corriger le tir de ces dernières, qui nous ont conduits dans les impasses écologiques que l'on sait. " Il existe trois niveaux de biomimétisme. Le premier consiste à imiter les formes de la nature. Le second, de plus en plus prisé des industriels, repose sur l'imitation des matériaux et des processus naturels. La vraie révolution repose cependant sur le troisième niveau, qui consiste à imiter les stratégies du vivant, sa philosophie. Ce troisième niveau a des implications fascinantes. Ainsi, contrairement à l'image que nous nous faisons de la " loi de la jungle ", la nature ne pratique la compétition que dans 10 % des rapports entre organismes. Les 90 % restants sont fondés sur la coexistence, le mutualisme, la coopération, le commensalisme, le parasitisme et la symbiose. A imiter absolument! (shrink)

Here a group of philosophers, economists and political theorists discuss the work of David Gauthier, which seeks to show that rational individuals would accept certain moral constraints on their choices. The possibilities and limitations of a contractarian approach to issues of justice is analyzed.

The Logic of Leviathan The Moral and Political Theory of Thomas Hobbes.

Is a rational morality a necessary evil—a mean between what an individual would judge best—bettering his situation at whatever cost to others, and worst—having one's situation worsened at other's pleasure? It would seem that Glaucon's fable of the ring of Gyges may be applied to our account of morality. And indeed, matters may be worse—a contractarian morality such as we have developed may seem to be a tool for the clever and strong to use in domination, using the language of (...) cooperation to conceal the reality of exploitation. If we understand ourselves on the model of economic man, treating all basic motivation as exemplifying asociality and all human relationships as contractual, we may find these conclusions hard to escape. Even though we could understand the rational arguments in support of morality, our feelings would be engaged only by our own concerns, and we would lack any affective capacity for morality. (shrink)

For several decades, David Gauthier has been one of the leading philosophers working on practical rationality and deliberation. This book presents a selection of Gauthier's writings on these topics, all but two of which were written after Morals by Agreement. They represent Gauthier's most important contributions to the theory of practical reason, moving some distance from the view a first presented in Reason and Maximization and developed in a much-reprinted chapter of Morals by Agreement. These essays challenge (...) common misconceptions of Gauthier's revisionist conception of practical rationality, and provide important insights with implications for economic theory. (shrink)

Feminist critics of the stigmatization of prostitution such as Martha Nussbaum and Sybil Schwarzenbach argue that the features of the practice do not, or at least need not, differ essentially from those of other more respected sorts of labor. I argue that even the least degraded forms of the current practice of prostitution remain objectionable on feminist grounds because patrons demand a semblance of sexual self-expression that engages discriminatory beliefs about women's sexuality.

'There is nothing either good or bad, but thinking makes it so.'l But if things considered in themselves are neither good nor bad, if there is no realm of value existing independently of animate beings and their activities, then thought is not the activity that summons value into being. Hume reminds us, 'Reason is, and ought only to be the slave of the passions', and while Hume's dictum has been widely disputed, we shall defend it.2 Desire, not thought, and volition, (...) not 'cognition, are the springs of good and evil. (shrink)

Rousseau is often portrayed as an educational and social reformer whose aim was to increase individual freedom. In this volume David Gauthier examines Rousseau's evolving notion of freedom, where he focuses on a single quest: can freedom and the independent self be regained? Rousseau's first answer is given in Emile, where he seeks to create a self-sufficient individual, neither materially nor psychologically enslaved to others. His second is in the Social Contract, where he seeks to create a citizen who (...) identifies totally with his community, experiencing his dependence on it only as a dependence on himself. Rousseau implicitly recognized the failure of these solutions. His third answer is one of the main themes of the Confessions and Reveries, where he is made for a love that merges the selves of the lovers into a single, psychologically sufficient unity that makes each 'better than free'. But is this response a chimaera? (shrink)

Is morality rational? In this book Gauthier argues that moral principles are principles of rational choice. He proposes a principle whereby choice is made on an agreed basis of cooperation, rather than according to what would give an individual the greatest expectation of value. He shows that such a principle not only ensures mutual benefit and fairness, thus satisfying the standards of morality, but also that each person may actually expect greater utility by adhering to morality, even though the (...) choice did not have that end primarily in view. In resolving what may appear to be a paradox, the author establishes morals on the firm foundation of reason. Gauthier's argument includes an account of value, linking it to preference and utility; a discussion of the curcumstances in which morality is unnecessary; and an application of morals by agreement to relations between peoples at different levels of development and different generations. Finally, he reflects on the assumptions about individuality and community made by his account of rationality and morality. (shrink)

The people's right to know and press rights to gather and publish information remain dominant justifications for controversial media activities. Yet, the power of the media to set the agenda for public discourse in our country warrants a careful analysis of these rights, their corresponding responsibilities, and their moral limits. This article examines the right to know and press freedom from the perspective of their shared purpose, facilitation of informed decision making. This article also demonstrates moral justification of limits on (...) right to know and press freedom based on traditional ethics theories and media impact on public discourse. (shrink)

David Gauthier; XII*—In the Neighbourhood of the Newcomb-Predictor (Reflections on Rationality), Proceedings of the Aristotelian Society, Volume 89, Issue 1, 1.

This papers attempts to bridge business ethics to corporate social responsibility including the social and environmental dimensions. The objective of the paper is to suggest an improvement of the most commonly used corporate environmental management tool, the Life Cycle Assessment (LCA). The method includes two stages. First, more phases are added to the life-cycle of a product. Second, social criteria that measure the social performance of a product are introduced. An application of this “extended” LCA tool is given.

Loudness is the magnitude of the auditory sensation that a listener experiences when exposed to a sound. Several sound attributes are reported to affect loudness, such as the sound pressure level at the listener's ears and the spectral content. In addition to these physical attributes of the stimulus, some subjective attributes also appear to affect loudness. When presented with a sound, a listener interacts with an auditory object and can focus on several aspects of the latter. Loudness appears to differ (...) depending on how listeners apprehend this object, notably whether they focus on the sound that reaches their ears or that is produced by the source. The way listeners focus on the auditory object may depend on the stimulus itself. For instance, they might be more likely to focus on the sound emitted by the source if the latter is visible. The instructions given by the experimenters can also explicitly direct the listener's focus on the sound reaching the ears or emitted by the source. The present review aims at understanding how listeners focus on the auditory object depending on the stimuli and instructions they are provided with, and to describe how loudness depends on this focus. (shrink)

Dans ce recueil, j'ai voulu regrouper des textes publiés en français et en anglais dans les vingt dernières années; ces textes font écho à mes recherches dans le domaine des fondements de la logique, des mathématiques et de la physique dans une perspective constructiviste depuis un demi-siècle. C'est donc un parcours fondationnel sur la longue durée que j'ai voulu reproduire sans négliger la dimension critique des enjeux scientifiques de la logique, des mathématiques et de la physique avec la vigilance philosophique (...) qui remet aussi bien en question la philosophie traditionnelle dans ses retranchements métaphysiques. Cet assemblage n'est pas un florilège, mais plutôt un pot-pourri de textes parus dans des revues qui ne sont pas facilement accessibles pour les papers en anglais qui composent un medley d'articles scientifiques sans musique, mais avec un leitmotiv et des thèmes majeurs récurrents.J'ai ajouté des commentaires introductifs pour chacun des articles pour les situer dans le temps de leur publication et dans les débats actuels touchant le savoir scientifique."--Page 4 de la couverture. (shrink)

The current interest in and discussion of virtue ethics suggests that this approach to moral decisionmaking has several distinct advantages as applied to ethical issues in healthcare delivery. For the most part, calls to incorporate the virtues of the healthcare provider in discussions of these issues have sought to supplement rather than totally replace traditional ethical theories, such as the utilitarian focus on maximizing the best overall consequences and the Kantian concern to act on the duty of respect for persons. (...) Including virtue-based ethics in such discussions allows for a more eclectic view of what should be considered in resolving difficult moral problems. As many critics of the purely principle-based approach have noted, real moral dilemmas are usually quite messy and are not easily susceptible to satisfactory resolution solely on the basis of abstract moral theories or principles. (shrink)

The principle of respect for autonomy is increasingly under siege as a valuable component of healthcare ethics. Its critics charge that it has been elevated to a position out of proportion to its contribution, so that the individual's wishes and rights have come to dominate healthcare decisionmaking, while obligations and responsibilities are ignored or devalued. If we are to salvage respect for autonomy we must find a way to reconnect the individual and the community, rights and responsibilities, in the way (...) we think about, discuss, and make healthcare decisions. (shrink)

The theme « Truth and Certainty » is reminiscent of Hegel’s dialectic of prominent in the Phänomenologie des Geistes, but I want to treat it from a different angle in the perspective of the constructivist stance in the foundations of logic and mathematics. Although constructivism stands in opposition to mathematical realism, it is not to be considered as an idealist alternative in the philosophy of mathematics. It is true that Brouwer’s intuitionism, as a variety of constructivism, (...) has idealistic overtones, but my main concern in this paper is located in the mathematical tradition of constructive mathematics from the Greeks to Fermat, Gauss and Kronecker, and from the logical side, in the finitist doctrine of Hilbert and his followers. (shrink)

Comment expliquer la persistance d’objets techniques ou scientifiques qui semblent en tout point dépassés? Cet article étudie ce problème, à travers un cas portant sur les modèles d’évaluation du passage de la radioactivité dans l’environnement. Ces modèles apparaissent dans les années 1950 et se fondent alors sur un coefficient unique. De nombreux problèmes conceptuels et pratiques concernant ce paramètre apparaissent et sont alors menés de nombreux travaux de développement d’alternatives à ces modèles qui semblent dépassés. Malgré cela, ceux-ci sont encore (...) aujourd’hui largement majoritaires. Nous expliquons cette situation a priori paradoxale par des raisons « pratiques » (coûts techniques, structure sociale de l’expertise) et avec des arguments fondés sur les fonctions des modèles et sur leurs usages. (shrink)

Internal logic is the logic of content. The content is here arithmetic and the emphasis is on a constructive logic of arithmetic (arithmetical logic). Kronecker's general arithmetic of forms (polynomials) together with Fermat's infinite descent is put to use in an internal consistency proof. The view is developed in the context of a radical arithmetization of mathematics and logic and covers the many-faceted heritage of Kronecker's work, which includes not only Hilbert, but also Frege, Cantor, Dedekind, Husserl and Brouwer. The (...) book will be of primary interest to logicians, philosophers and mathematicians interested in the foundations of mathematics and the philosophical implications of constructivist mathematics. It may also be of interest to historians, since it covers a fifty-year period, from 1880 to 1930, which has been crucial in the foundational debates and their repercussions on the contemporary scene. (shrink)

Dans cet essai de cosmologie sauvage, je ne me suis pas adressé aux marquises et aux abbesses, comme le fit Fontenelle, mon lointain prédécesseur, en son temps. Mon public est profane et il refuse d'emblée la docte ignorance (docta ignorantia) des métaphysiciens et des mystiques, femmes savantes ou esprits crédules. Il se méfie aussi bien des mystifications dont se parent parfois les savants et les scientifiques, aussi bien que des fabulations des auteurs de science-fiction, mais il tend l'oreille souvent aux (...) poètes, écrivains et philosophes inquiets. La cosmologie ou théorie de l'univers est-elle possible et n'est-elle pas limitée par un horizon, l'horizon du visible ou de l'observable? Imaginer un au-delà de l'horizon est la tâche de la cosmologie spéculative qui a remplacé la métaphysique et qui prend alors la relève de la mythologie pour inventer la scène primitive d'une mer originelle. Cette eau originaire, que l'on retrouve chez Thalès dans la philosophie grecque présocratique, n'est pas si éloignée des fluctuations du vide quantique et le mythe de l'océan primitif peut être perçu comme la matrice de toutes les cosmogonies. Mais qui n'abordera jamais les rives de l'origine? La limite antérieure de l'origine rejoint la limite de l'horizon : toutes deux sont récessives et l'on ne peut concevoir l'univers que comme une sphère, ce qu'un autre penseur présocratique, Parménide, avait bien vu. C'est dans cette sphère que l'observateur local se tient et tient ensemble l'origine et l'horizon pour mesurer l'empan de l'univers, avec la Terre en son centre. (shrink)

Cette livraison spéciale de l'importante revue philosophique Philosophische Rundschau propose un tour d'horizon critique de la « logique des sciences sociales. » L'auteur, professeur à l'Université de Francfort, nous présente une synthèse magistrale de l'epistémologie contemporaine des sciences sociales en deux cents pages d'un texte serré.

Journal of Mass Media Ethics, Volume 27, Issue 2, Page 157-159, April-June.

The notion of transcendental observer (transcendentaler Zuschauer) is introduced in Husserl’sCartesianische Meditationen.The idea of the observer first appears in Kant’s Copernican revolution putting the emphasis on the observer as he announces in hisKritik der reinen Vernunft.Contemporary physics also has a notion of a local observer and it plays a central role in the foundations of quantum mechanics, general relativity and cosmology.