Even though female food acquisition is an area of considerable interest in hunter-gatherer research, the ecological determinants of women’s economic decisions in these populations are still poorly understood. The literature on female foraging behavior indicates that there is considerable variation within and across foraging societies in the amount of time that women spend foraging and in the amount and types of food that they acquire. It is possible that this heterogeneity reflects variation in the trade-offs between time (...) spent in food acquisition and child care activities that women face in different groups of hunter-gatherers. In this paper we discuss the fitness trade-offs between food acquisition and child care that Hiwi and Ache women foragers might face. Multiple regression analyses show that in both populations the daily food acquisition of a woman’s spouse is negatively related to female foraging effort. In addition, nursing mothers spend less time foraging and acquire less food than do nonnursing women. As the number of dependents that a woman has increases, however, women also increase foraging time and the amount of food they acquire. Some interesting exceptions to these general trends are as follows: (a) differences in foraging effort between nursing and nonnursing women are less pronounced when fruits and roots are in season than in other seasons of the year; (b) foraging return rates decrease for Ache women as their numbers of dependents increase; and (c) among Ache women, the positive effect of number of dependents on foraging behavior is less pronounced when fruits are in season than at other times of the year. Lastly, in the Hiwi sample we found that postreproductive women work considerably harder than women of reproductive age in the root season but not in other seasons of the year. We discuss how ecological variation in constraints, the number of health insults to children that Hiwi and Ache mothers can avoid, and the fitness benefits they can gain from spending time in food acquisition and child care might account for differences and similarities in the foraging behaviors of subgroups of Hiwi and Ache mothers across different seasons of the year. Valid tests of the explanations we propose will require considerable effort to measure the relationship between maternal food acquisition, child care, and adverse health outcomes in offspring. (shrink)

Rice is the most important crop species on earth, providing staple food for 70% of the world's human population. Over the past four decades, successes in classical breeding, fertilization, pest control, irrigation and expansion of arable land have massively increased global rice production, enabling crop scientists and farmers to stave off anticipated famines. If current projections for human population growth are correct, however, present rice yields will be insufficient within a few years. Rice yields will have to increase by (...) an estimated 60% in the next 30 years, or global food security will be in danger. The classical methods of previous green revolutions alone will probably not be able to meet this challenge, without being coupled to recombinant DNA technology. Here, we focus on the promise of these modern technologies in the area of nitrogen acquisition in rice, recognizing that nitrogen deficiency compromises the realization of rice yield potential in the field more than any other single factor. We summarize rice‐specific advances in four key areas of research: (1) nitrogen fixation, (2) primary nitrogen acquisition, (3) manipulations of internal nitrogen metabolism, and (4) interactions between nitrogen and photosynthesis. We develop a model for future plant breeding possibilities, pointing out the importance of coming to terms with the complex interactions among the physiological components under manipulation, in the context of ensuring proper targeting of intellectual and financial resources in this crucial area of research. BioEssays 26:683–692, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

The transfer of food among group members is a ubiquitous feature of small-scale forager and forager-agricultural populations. The uniqueness of pervasive sharing among humans, especially among unrelated individuals, has led researchers to evaluate numerous hypotheses about the adaptive functions and patterns of sharing in different ecologies. This article attempts to organize available cross-cultural evidence pertaining to several contentious evolutionary models: kin selection, reciprocal altruism, tolerated scrounging, and costly signaling. Debates about the relevance of these models focus primarily on the (...) extent to which individuals exert control over the distribution of foods they acquire, and the extent to which donors receive food or other fitness-enhancing benefits in return for shares given away. Each model can explain some of the variance in sharing patterns within groups, and so generalizations that ignore or deny the importance of any one model may be misleading. Careful multivariate analyses and cross-cultural comparisons of food transfer patterns are therefore necessary tools for assessing aspects of the sexual division of labor, human life history evolution, and the evolution of the family. This article also introduces a framework for better understanding variation in sharing behavior across small-scale traditional societies. I discuss the importance of resource ecology and the degree of coordination in acquisition activities as a key feature that influences sharing behavior. (shrink)

Living in poverty is associated with high levels of protracted stress associated with health problems. Economic and food insecurity are particularly poignant aspects of poverty and condition the work of securing basic daily needs of families. Recent studies suggest that levels of stress increase as family food needs rise. This paper presents new findings which clarify the relationship of food provisioning to stress levels, by examining actual food provisioning strategies and food insecurity among the Northern (...) Cheyenne Indians of southeastern Montana. Results clearly show that stress varies by types of food acquisition strategies. Contrary to our expectations, more complex strategies, including relatively unpredictable and cumbersome food provisioning activities, are not linked to higher stress levels in our analysis. Controlling for food security levels, households using a combination of local programs and informal subsistence sources are the least stressed, despite the demands of managing a large number of food sources. Households primarily using Food Stamps are the most likely to experience high levels of stress. Interviews with Food Stamp recipients show that potential sources of stress include inadequate allocations of Food Stamps, difficulty achieving and maintaining eligibility, challenges to complying with paperwork and appointment requirements, as well as personal obstacles and community barriers to making food stamps last. Analyses indicate that contradictions between local cultural norms for food provisioning and the realities of food insecurity in this context promote strategies emphasizing greater independence from federal food programs. (shrink)

This paper distinguished different analytical approaches to the evaluation of the sustainability of large-scale land acquisitions—at both the conceptual and methodological levels. First, at the conceptual level, evaluation of the sustainability of land acquisitions depends on what definition of sustainability is adopted—strong or weak sustainability. Second, a lack of comparative empirical methods in many studies has limited the identification of causal factors affecting sustainability. An empirical investigation into the sustainability of land acquisitions in Tanzania that employs these existing concepts in (...) a methodologically rigorous manner offers an opportunity to more clearly addresses ethical questions surrounding international land acquisitions. My findings indicate that it should not be assumed that sustainability necessarily hinges on issues of strong sustainability, particularly that all village lands represent critical natural capital. As a result of its unique history of Ujamaa villagization, Tanzania villages often have ownership of significant tracts of unused land that mitigates the risk of violating conditions of strong sustainability. Issues of weak sustainability appear to be more important to villagers—particularly the degree of man-made capital benefits derived from projects. While compensation rates for lands acquired were low and the process lacked transparency, low compensation rates are not sufficient grounds for rejecting land acquisitions as unsustainable. When projects deliver significant man-made capital benefits, low compensation rates were not a politically salient issue amongst villagers. Finally, results suggest that some prioritization of man-made capital over biodiversity can be ethically defensible when the decision-making process goes through legitimate village government bodies and benefits reach poor villagers. (shrink)

Community supported agriculture programs are transforming the way people relate to food and agriculture. Many researchers have considered the transformative potential of CSAs on economic, social, and environmental relations. They illustrate how participants are embedded in broader political economic transformations. The same focus, however, has not been given to CSAs’ transformative impact on individual shareholders—especially in terms of their relationship to food and health. We draw together literatures from behavioral economics, econometrics, and political ecology to evaluate the potential (...) impacts of CSA participation on food lifestyle behaviors. Using primary data drawn from a survey of four groups with distinct food acquisition environments, we compare respondents’ self-assessed food-related behaviors along three different categories: produce versus processed food consumption, food away from home consumption, and food acquisition and interest in nutrition. By documenting between-group differences, we confirm that shareholders display significant absolute differences to other groups along numerous indicators related to the above-stated categories and in general assessments of health. These differences correspond directionally to behaviors public health officials identify as correlated to beneficial health outcomes. We conclude by theorizing how the food environments delineated by a CSA exchange relationship provide unique reflexive opportunities for participants to develop diverse food-related skills and behaviors. (shrink)

Children show a remarkable degree of consistency in learning some words earlier than others. What patterns of word usage predict variations among words in age of acquisition? We use distributional analysis of a naturalistic corpus of child‐directed speech to create quantitative features representing natural variability in word contexts. We evaluate two sets of features: One set is generated from the distribution of words into frames defined by the two adjacent words. These features primarily encode syntactic aspects of word usage. (...) The other set is generated from non‐adjacent co‐occurrences between words. These features encode complementary thematic aspects of word usage. Regression models using these distributional features to predict age of acquisition of 656 early‐acquired English words indicate that both types of features improve predictions over simpler models based on frequency and appearance in salient or simple utterance contexts. Syntactic features were stronger predictors of children's production than comprehension, whereas thematic features were stronger predictors of comprehension. Overall, earlier acquisition was predicted by features representing frames that select for nouns and verbs, and by thematic content related to food and face‐to‐face play topics; later acquisition was predicted by features representing frames that select for pronouns and question words, and by content related to narratives and object play. (shrink)

This paper presents quantitative data on altruistic cooperation during food acquisition by Ache foragers. Cooperative activities are defined as those that entail a cost of time and energy to the donor but primarily lead to an increase in the foraging success of the recipient. Data show that Ache men and women spend about 10% of all foraging time engaged in altruistic cooperation on average, and that on some days they may spend more than 50% of their foraging time (...) in such activities. The most time-consuming cooperative activity for both sexes is helping during the pursuit of game animals, a pattern that is probably linked to the widespread sharing of game by Ache foragers. Cooperative food acquisition and subsequent food redistribution in hunter-gatherer societies are critical behaviors that probably helped shape universal, evolved, cooperative tendencies that are well illustrated in modern experimental economics. (shrink)

Proponents of large-scale land acquisitions (LaSLA) argue that poor countries could benefit from foreign direct investment in land (World Bank 2011), while opponents argue that LaSLA is nothing more than neo-colonial theft of poor peasants’ livelihoods, i.e., land grabbing (Borras and Franco in Yale Hum Rights Dev L J, 13: 507–523, 2010a). To ensure responsible agricultural investments (RAI), a voluntary “code of conduct” for land acquisitions has been proposed by the World Bank (2011) and the FAO (2012). A critical reaction (...) to the “code of conduct” approach is the proposal for a set of minimum human rights principles, suggested by the UN Special Rapporteur on the Right to Food, De Schutter (2009). Even more critical of the “code of conduct” approach are Borras and Franco in Yale Hum Rights Dev L J, 13(2): 507–523, 2010a, who propose empowering small-scale farmers by giving them land sovereignty so that they are assured control over their land. This paper is a review of the governance and ethics issues connected to LaSLA. It has four main objectives: First, it offers a critical presentation of three major governance approaches to LaSLA: the “liberal code of conduct” (FAO and the World Bank), the ‘critical liberal human rights’ approach (De Schutter) and the ‘Marxist’ approach (Borras and Franco). Second, it discusses the notion of a human right to land, with reference to John Locke’s theory of appropriating land. Third, it discusses the issue of ensuring an inclusive process in LaSLA. Finally, an argument is made for instituting a (global) obligation to refrain from participating in or benefitting from institutional schemes that facilitate negative land grabbing (Pogge in Politics as usual: what lies behind the pro-poor rhetoric? Polity Press, Cambridge 2010). (shrink)

Macphail’s (1985) null hypothesis challenged researchers to demonstrate any differences in intelligence between vertebrate species. Rather than focus on differences, we asked whether rats would show the same unexpected, counterintuitive features of skill learning observed in humans: Factors that degrade performance during acquisition often enhance performance in a subsequent retention/autonomy phase. Providing post-trial “knowledge of results” (KR) on 30%-67% of trials instead of 100% degrades accuracy, yet increases retention in a subsequent phase without KR. We tested this feature by (...) providing three groups of rats with KR on every trial (100% KR), 67% KR, or 0% KR. We also provided operant feedback in every trial for completing the left-right lever-press skill (food for correct sequences, timeout for all others). In the autonomy phase, we assessed their ability to complete the skill independently—in the absence of differential cues and KR feedback. In agreement with human performance in the autonomy phase, 67% KR yielded higher skill accuracy than providing 100% KR. Also, providing 67% KR improved skill accuracy above that observed with operant feedback alone (0% KR). Rather than degrading performance during acquisition, the 67% KR condition yielded unexpected higher accuracy than the other conditions. Accuracy increased systematically across our extended acquisition phase, which provided each rat with over 3600 trials compared to 20-30 trials for human studies. Providing limited KR promoted skill learning in rats as it does in humans, consistent with the conjecture that both species share common learning processes. Introducing difficulties to rats during training improved their autonomy. (shrink)

This article argues that the definition of land grabs in public debate is a politically contested process with profound normative consequences for policy recommendations regarding the future of the family farm model. To substantiate this argument, I first explore how different definitions of land grabbing bring into focus different kinds of actors and briefly survey the history of land grabbing in Canada. I then introduce the public debate about land grabbing in Québec and discuss its evolution from its beginning in (...) 2009 up until the provincial public inquiry on land grabs in March 2015. Here, I make critical observations regarding each participant’s position, showing how different definitions of land grabbing has significant implications for policy recommendation and the promotion of different agricultural business models. More specifically, I emphasize how these discussions crucially fail to consider indigenous people’s land rights and ignore the constraints imposed by the corporate food regime on family farms. I conclude by suggesting that the adoption of a food sovereignty approach to land governance helps redirect attention to these important issues and provide insight into imagining more sustainable alternative models of agriculture. (shrink)

To determine the effects of early undernutrition on learning and long-term memory, Swiss mice were cross-fostered randomly at birth to produce litter sizes of 6 and 16, thereby providing “normally nourished” and “undernourished” conditions. At 28 days of age, the pups were housed in groups of 3 and 4, with ad-lib access to food and water until testing began at 60 days of age. Each mouse received 50 active-avoidance training trials daily for 14 consecutive days. Retention testing began 14 (...) days after the end of original training and consisted of 50 trials daily for 5 days. Overall, mice reared in large litters suffered deficits in learning but not in long-term memory. (shrink)

During the 2007–2008 global food crisis, the prices of primary foods, in particular, peaked. Subsequently, governments concerned about food security and investors keen to capitalize on profit-maximizing opportunities undertook large-scale land acquisitions (LASLA) in, predominantly, least developed countries (LDCs). Economically speaking, this market reaction is highly welcome, as it should (1) improve food security and lower prices through more efficient food production while (2) host countries benefit from development opportunities. However, our assessment of the debate on (...) the issues indicates critical voices in both the media and academic discourse. This article aims to provide a philosophical law and economics analysis. We draw on John Rawls’s Theory of Justice, focusing on Rawls’s background institutions for distributive justice (§43) to evaluate LASLA form an ethical angle. Approaching LASLA into Sub Saharan LDCs as a socio-economic reform redistributing land from the local population of LDCs to investors, we acknowledge that they bear a highly desirable potential. Often, though, they cannot be regarded as ethically correct in practice as the insignificant improvements for local populations and sometimes even human rights violations contradict Rawls’s principles of justice. Then investigating whether and how international law can help overcome the shortcomings, we conclude that even though respective mechanisms exist in the current state of international law, it is hardly possible that it will produce more just outcomes in the near future. (shrink)

Large-scale transnational land acquisition of agricultural land in the global south by rich corporations or countries raises challenging normative questions. In this article, the author critically examines and advocates a human rights approach to these questions. Mutually reinforcing, policies, governance and practice promote equitable and secure land tenure that in turn, strengthens other human rights, such as to employment, livelihood and food. Human rights therefore provide standards for evaluating processes and outcomes of transnational land acquisitions and, thus, for (...) determining whether they are ethically unacceptable land grabs. A variety of recent policy initiatives on the issue have evoked human rights, most centrally through the consultation and negotiation of the Voluntary Guidelines on the Responsible Governance of Tenure of Land, Fisheries and Forests concluded in 2012. However, a case of transnational land appropriation illustrates weak host and investor state enforcement of human rights, leaving the parties to in interaction with local groups in charge of protecting human rights. Generally, we have so far seen limited direct application of human rights by states in their governance of transnational land acquisition. Normative responses to transnational land acquisition—codes of conduct, principles of responsible agricultural investment or voluntary guidelines—do not in themselves secure necessary action and change. Applying human rights approaches one must therefore also analyze the material conditions, power relations and political processes that determine whether and how women and men can secure the human rights accountability of the corporations and governments that promote large-scale, transnational land acquisition in the global south. (shrink)

The paper looks into one branch of Ukrainian economy - the food industry. It is established that marketing activities of food industry companies have some specific features, namely mismatching of an agricultural performance period and production time; a perishable nature of products, which necessitates tight time frames of storage and sales; production focus on the direct consumer; a high level of materials consumption of products released, which requires a large quantity of feedstock as well as high qualification skills (...) and expertise from workers. The activity of a domestic bakery is described. It is determined that the complexity of its production processes and increased information flows requiring in-line processing for acquisition of appropriate data served as a basis for introduction of the special 'Marketing' software by its Marketing Department. The conducted analysis of the information product allowed to establish that the user of the above software maintains routine accounting and control of product supplies. To that end, information is processed, parameters related to production and supplies analyzed. The software significantly improves operational efficiency owing to an increased number of accountable factors and reduced decision making time. That bundled software however makes no provisions for development of a unified integrated management system, which reduces the company operating efficiency. It is established that to date there are many information systems available for food production automation, the Oracle E-Business Suite-based technology, developed by TopS BI, among them. It was offered for application at the food enterprise in question. The above system allows to automate production planning and management processes at various levels: from daily shop planning and management with step-by-step product quality control to scaled-up calendar planning of production, including that for a group of enterprises. (shrink)

Food, money, and time are exchangeable resources essential for survival and reproduction. Individuals live within finite budgets of these resources and make tradeoffs between money and time when making intertemporal choices between an immediate smaller reward and a delayed lager reward. In this paper, I examine signaling functions of blood glucose in regulating behaviors related to resource regulations beyond caloric metabolisms. These behavioral regulations include choices between energy expenditure and energy conservation, monetary intertemporal choices, and self-control in overcoming temptations. (...) I begin by comparing potential embodied signals for resource forecasting and proactive decision making in terms of their pros and cons as a signal for regulating both metabolism and behavioral decision making and self-control. Based on this analysis, circulating glucose emerges as not only the designated fuel for brain metabolism but also a privileged resource forecasting signal for regulating immediate, short-term, and long-term behavioral adaptations to the resource budget of the decision maker. In the context of an on-going debate between the limited resource model and the motivation accounts of behavioral effects of blood glucose, I propose a dual functions (caloric provision and resource forecasting) and dual signaling (glucose taste and ingestion) hypothesis of circulating glucose in resource management, and provide behavioral and neurophysiological evidence of the separate effects of glucose taste to motivate effort for resource acquisition and glucose ingestion to promote resource conservation and future orientation. Accumulating evidence indicates that the body is able to detect fake signals of non-caloric sweeteners and react to such “caloric crisis” with an enhanced preference for immediate rewards over future rewards, revealing the wisdom of the body. (shrink)

Criminologists have long acknowledged the link between a number of cognitive deficits, including low intelligence and impulsivity, and crime. A new wave of research has demonstrated that pharmacological intervention can restore or improve cognitive function, particularly executive function, and restore neural plasticity. Such restoration and improvement can allow for easier acquisition of new skills and as a result, presents significant possibilities for the criminal justice system. For example, studies have shown that supplements of Omega-3, a fatty acid commonly found (...) in food such as tuna, can decrease frequency of violent incidents in an incarcerated population. Research has also begun to explore the use of selective serotonin reuptake inhibitors to reduce impulsivity in some violent offenders. However, there are significant legal and ethical implications when moving from dietary supplements to prescription pharmaceuticals and medical devices for cognitive intervention. This paper will explore the legal and ethical issues surrounding the use of pharmacological intervention on prisoners as an effort to reduce crime and recidivism. (shrink)

Veganic agriculture, often described as farming that is free of synthetic and animal-based inputs, represents an alternative to chemical-based industrial agriculture and the prevailing alternative, organic agriculture, respectively. Despite the promise of veganic methods in diverse realms such as food safety, environmental sustainability, and animal liberation, it has a small literature base. This article draws primarily on interviews conducted in 2018 with 25 veganic farmers from 19 farms in the United States to establish some baseline empirical research on this (...) farming community. Its qualitative perspectives illuminate farmer perceptions of and experiences with veganic growing, including definitions, knowledge acquisition, values, and challenges. Results highlight a lack of agreement about the meaning of veganic agriculture in terms of allowable inputs and scope. Participants have drawn on a wide array of veganic and non-veganic resources to ascend their veganic production learning curves, also relying on experimentation and trial-and-error. Their farming is motivated by a diversity of real and perceived benefits, most notably consistency with veganism, food safety advantages, and plant and soil health benefits. Veganic product sourcing and the dearth of veganic agriculture-specific resources present considerable challenges to farmers. The article briefly discusses possibilities for developing veganic agriculture in the United States, such as through a US-based certification system and farmers’ associations, based on considerations of the trajectory of the US organic farming movement and veganic developments in Europe. Finally, the article suggests the importance of expanded research into soil health and fertility in plant-based systems to support practicing and potential veganic farmers. (shrink)

Anthropological tests of patch choice models from optimal foraging theory have primarily employed acquisition rates as the currency of the model. Where foragers share their returns, acquisition rates may not be similar to consumption rates and thus may not be an appropriate currency to use when modeling foraging decisions. Indeed, on Ifaluk Atoll the distribution patterns of fish vary by fishing method and location. Previous analyses of Ifaluk patch choice decisions suggested that if Ifaluk fishers are trying to (...) maximize their production rates they should rarely torch fish for dogtoothed tuna. However, some men do spend considerable time and energy exploiting the dogtoothed tuna patch. To improve our understanding of the constraints and motivations influencing men’s decisions to exploit this patch, here I use per capita consumption rates as a currency, rather than production rates, to evaluate predictions generated from a patch choice model. Results indicate that although fish caught in other patches are more widely distributed than fish caught in the dogtoothed tuna patch, the consumption rates of torch fishers and their kin are still considerably lower than the consumption rates of men pursuing fish in other patches. Although these results are unable to explain why Ifaluk men exploit the dogtoothed tuna patch, an important explanatory hypothesis is eliminated. (shrink)

Issues arising in connection with genes and nutrition policy include both nutrigenomics and nutrigenetics. Nutrigenomics considers the relationship between specifc nutrients or diet and gene expression and, it is envisaged, will facilitate prevention of diet-related common diseases. Nutrigenetics is concerned with the effects of individual genetic variation on response to diet, and in the longer term may lead to personalised dietary recommendations. It is important also to consider the surrounding context of other issues such as novel and functional foods in (...) so far as they are related to genetic modification. Ethical issues fall into a number of categories: why nutrigenomics? Will it have important public health benefits? questions about research, e.g. concerning the acquisition of information about individual genetic variation; questions about who has access to this information, and its possible misuse; the applications of this information in terms of public health policy, and the negotiation of the potential tension between the interests of the individual in relation to, for example, prevention of conditions such as obesity and allergy; the appropriate ethical approach to the issues, e.g. the moral difference, if any, between therapy and enhancement in relation to individualised diets; whether the 'technological fix' is always appropriate, especially in the wider context of the purported lack of public confidence in science, which has special resonance in the sphere of nutrition. (shrink)

Advances in neuromodulation and an improved understanding of the anatomy and circuitry of psychopathology have led to a resurgence of interest in surgery for psychiatric disease. Clinical trials exploring deep brain stimulation (DBS), a focally targeted, adjustable and reversible form of neurosurgery, are being developed to address the use of this technology in highly selected patient populations. Psychiatric patients deemed eligible for surgical intervention, such as DBS, typically meet stringent inclusion criteria, including demonstrated severity, chronicity and a failure of conventional (...) therapy. Although a humanitarian device exemption by the US Food and Drug Administration exists for its use in obsessive-compulsive disorder, DBS remains a largely experimental treatment in the psychiatric context, with its use currently limited to clinical trials and investigative studies. The combination of a patient population at the limits of conventional therapy and a novel technology in a new indication poses interesting challenges to the informed consent process as it relates to clinical trial enrollment. These challenges can be divided into those that relate to the patient, their disease and the technology, with each illustrating how traditional conceptualisations of research consent may be inadequate in the surgical psychiatry context. With specific reference to risk analysis, patient autonomy, voluntariness and the duty of the clinician-researcher, this paper will discuss the unique challenges that clinical trials of surgery for refractory psychiatric disease present to the consent process. Recommendations are also made for an ethical approach to clinical trial consent acquisition in this unique patient population. (shrink)

Background HIV prevention trials conducted among disadvantaged vulnerable at-risk populations in developing countries present unique ethical dilemmas. A key concern in bioethics is the validity of informed consent for trial participation obtained from research subjects in such settings. The purpose of this study was to investigate the effectiveness of a continuous informed consent process adopted during the MDP301 phase III vaginal microbicide trial in Mwanza, Tanzania. Methods A total of 1146 women at increased risk of HIV acquisition working as (...) alcohol and food vendors or in bars, restaurants, hotels and guesthouses have been recruited into the MDP301 phase III efficacy and safety trial in Mwanza. During preparations for the trial, participatory community research methods were used to develop a locally-appropriate pictorial flipchart in order to convey key messages about the trial to potential participants. Pre-recorded audio tapes were also developed to facilitate understanding and compliance with gel-use instructions. A comprehension checklist is administered by clinical staff to all participants at screening, enrolment, 12, 24, 40 and 50 week follow-up visits during the trial. To investigate women's perceptions and experiences of the trial, including how well participants internalize and retain key messages provided through a continuous informed consent process, a random sub-sample of 102 women were invited to participate in in-depth interviews conducted immediately after their 4, 24 and 52 week follow-up visits. Results 99 women completed interviews at 4-weeks, 83 at 24-weeks, and 74 at 52 weeks. In all interviews there was evidence of good comprehension and retention of key trial messages including that the gel is not currently know to be effective against HIV; that this is the key reason for conducting the trial; and that women should stop using gel in the event of pregnancy. Conclusions Providing information to trial participants in a focussed, locally-appropriate manner, using methods developed in consultation with the community, and within a continuous informed-consent framework resulted in high levels of comprehension and message retention in this setting. This approach may represent a model for researchers conducting HIV prevention trials among other vulnerable populations in resource-poor settings. Trial registration Current Controlled Trials ISRCTN64716212. (shrink)

Over 35 years ago, Meltzoff and Moore (1977) published their famous article ‘Imitation of facial and manual gestures by human neonates’. Their central conclusion, that neonates can imitate, was and continues to be controversial. Here we focus on an often neglected aspect of this debate, namely on neonatal spontaneous behaviors themselves. We present a case study of a paradigmatic orofacial ‘gesture’, namely tongue protrusion and retraction (TP/R). Against the background of new research on mammalian aerodigestive development, we ask: How does (...) the human aerodigestive system develop and what role does TP/R play in the neonate’s emerging system of aerodigestion? We show that mammalian aerodigestion develops in two phases: (1) from the onset of isolated orofacial movements in utero to the post-natal mastery of suckling at 4 months after birth, and; (2) thereafter, from preparation to the mastery of mastication and deglutition of solid foods. Like other orofacial stereotypies, TP/R emerges in the first phase and vanishes prior to the second. Based upon recent advances in activity-driven early neural development, we suggest a sequence of three developmental events in which TP/R might participate: the acquisition of tongue control, the integration of the central pattern generator for TP/R with other aerodigestive CPGs, and the formation of connections within the cortical maps of S1 and M1. If correct, orofacial stereotypies are crucial to the maturation of aerodigestion in the neonatal period but also unlikely to co-occur with imitative behavior. (shrink)

In July 2012, based on evidence from two major trials, the United States Food and Drug Administration approved the use of combined oral tenofovir/emtricitabine as pre-exposure prophylaxis for people at high risk of HIV acquisition. PrEP effectiveness is marred by poor adherence, however, even in trial populations, thus it is not a magic bullet for HIV prevention. It is, however, the most effective biomedical HIV prevention intervention available for people at high risk of HIV, particularly those who have (...) receptive sex and lack the power to negotiate condom use. Accordingly, there are compelling reasons to compare future experimental HIV prevention interventions against PrEP. The interests both of trial participants and of science are served by using PrEP as comparator: Not only would HIV incidence be reduced, but also the question of whether new interventions were superior to best proven interventions, in a given setting, would be answered comprehensively. (shrink)

Summary Classical Greek armies and navies moving through the territory of friendly, allied, and neutral city-states provisioned themselves through markets organized and controlled by those city-states. No scholar has ever explained why this was so. By placing this practice within a comparative framework, this article demonstrates that the protocol of the provision of markets by poleis to passing armies developed in the way it did in the late Archaic and early Classical Greek world because Greek states in this period lacked (...) the logistical structures to exert sustained coercive power against other states. Once the protocol was established, however, it continued in use throughout the Classical period even after fifth-century Athenian navies gained the logistical capacity to apply prolonged strategic pressure on coastal and island poleis. Use of the protocol continued because traditions of autonomy as well as long-standing customs governing relations between states restrained even the Aegean-dominating Athenians from using more forceful means of acquisition than markets to acquire their food from other poleis. (shrink)

At the time of the First Crusade, numerous factors fed the tension between the Byzantines and those Western Europeans who traveled through imperial lands. However, one of these factors - the supply of food - is often assumed or taken for granted. The purpose of this article is to examine the impact that the acquisition of food had on relations between the purported allies. It seems that during the First Crusade, at a critical juncture in their ongoing (...) social and political relationship, the supply of food seriously undermined relations between the crusaders and the Byzantines, gravely tarnishing political and military negotiations, and setting a precedent that clouded future interaction. Further, logistical issues appear to shed light on divisions among the social classes, namely, how individuals in the same army, but of different backgrounds, might interpret a similar event in distinctive ways. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reason m Seneca JOSIAH B. GOULD MAx POHLENZ,in his last great work on the Stoa,1 maintained that Logos is the central concept of Stoic philosophy (I, 34). Neither Mette2nor Edelstein,3each of whom reviewed Pohlenz's study, notes the author's frequent reminders that Stoicism is "eine Logosphilosophie" and his contention, set forth early in Volume I, that the concept of Logos has in Stoic philosophy "pushed wholly to one side the (...) Aristotelian J,o~sin doctrine as well as in terminology." One who is familiar with the fragments of the writings of the early Stoics hardly needs to be told that for Zeno, Cleanthes, and Chrysippus, Logos is a fundamental notion. Help is needed when one tries to make clear to himself the content of this notion. An example is the moral philosophy of Chrysippus as we have reconstructed it from the fragments of his writings. For Chrysippus the basic expression in Stoic moral philosophy, "life in accordance with nature" (zb ~arh ~b~Lu~'~u) becomes "life in accordance with reason" (r~ KaTh~,bTou~'~). I have, however, found it difficult to render an account of what, for Chrysippus, it would be to live in accordance with Logos or reason. On one hand, it would appear that to live in conformity with reason is to be guided by cumulative experience or generalizations from past experience about what would or would not be advantageous. It seems, that is, to be assent to reason when it passes from experience of this benefit following on that action to judgments such as "that kind of action issues in this kind of advantage." On the other hand, reason or Logos, in a fully developed state, we are informed, is the knowledge of genuinely good and genuinely bad things; and such knowledge is obviously not the kind of thing to be induced from particular experiences. In the first place a judgment that a particular consequence of a particular deed is of value presupposes the knowledge which Chrysippus describes as the "knowledge of things really good or really advantageous." For example, given that one has a relatively clear notion as to what health is, he with some experience, can judge whether or not this food and that activity contribute to health. But, on Chrysippus' view, it would seem that reason or Logos in order to come to conclusions about the value of health-inducing foods or activities has to possess a relatively clear notion about the value of something else in whose acquisition health is instrumental. The assertion that actions leading to health or wealth have value could not follow from some special insight by Logos into the intrinsic worth of health or wealth, for it is explicitly denied that they are unqualifiedly good. The question then arises whether Logos has an insight into 1Max Pohlenz, Die Stoa. Geschichte einer geistigen Bewegung. 2nd. ed. (GSttingen: Vandenhoeck & Rupreeht, 1959). H. J. Mette, Max Pohlenz: Die Stoa. Geschichte einer geistigen Bewegung. 2 Bde. (G6ttingen : Vandenhoeck und Ruprecht). Review, GnomonXXIII (1951),27-39. Ludwig Edelstein, Max Pohlenz. Die Stoa. Geschichte einer geistigen Bewegung. (GSttingen : Yandenhoeck und Ruprecht, I [1948},490 pp.; II [1949],230 pp.). Review,American Journal of Philology, LXXII (Oct., 1951),426--432. [13] 14 HISTORY OF PHILOSOPHY something else which is genuinely good by reference to which judgments can be made about the value of health and wealth under certain conditions. The suspicion that this is so is heightened by the exalted status assigned to the wise man. The ideal of the wise man does not fit snuglywith Chrysippus' conception of Logos as a generalizing instrument for determining what things and activities are useful. The wise man is too contemptuous of or, at least, too indifferent toward the "goods" of the world. It is unthinkable that he should attend to them with a view to determining which of them is useful. He knows already; his wisdom comes from other parts. He is sure of what is really good because an unobfuscated reason or Logns has declared this to him in an immediate way; he has not had to wait for the verdict of reason's generalizations on experience. It is difficult to ignore either of... (shrink)

While philosophers of science have marginally discussed concepts such as ‘nutrient’, ‘naturalness’, ‘food’, or the ‘molecularization’ of nutrition, they have yet to seriously engage with the nutrition sciences. In this paper, I offer one way to begin this engagement by investigating conceptual challenges facing the burgeoning field of nutritional ecology and the question of how organisms construct a ‘balanced’ diet. To provide clarity, I propose the distinction between nutrient balance as a property of foods or dietary patterns and nutrient (...) balancing as an evolved capacity to regulate nutrient intake. This distinction raises conceptual and empirical issues, such as what properties constitute this capacity and whether they are the same in all organisms. Additionally, while scientists use the term ‘balancing’, its intension and extension need further clarification. Based on the literature, the properties of external nutrient detection, internal sensing of nutrient levels, and organismal regulation could provide a basic recipe for nutrient balancing. Next, using an evolutionary lens, I examine nutrient acquisition in some prokaryotes, slime molds, simple multicellular eukaryotes, and in the quirks of multicellular metabolism to raise questions about the origins and universality of balancing. Finally, I build on this explication of balance and balancing by considering how obesity and cancer might respectively elucidate problems of organismal nutrient imbalances versus disrupted cellular nutrient balancing. (shrink)

The chicken meat, or broiler, business in the United States is a vertically integrated industry in which integrator corporations control all aspects of the business. Primarily through a series of business acquisitions, an industry duopoly has evolved. The two dominant integrator corporations, Pilgrim's Pride and Tyson Foods, are profitable, and their officers and stockholders benefit from the corporations’ financial success. The multitude of local growers who nurture the chickens to maturity for the integrators, however, benefit minimally from the financial success (...) of the integrators, as the growers face a myriad of financial, environmental, community, and health problems. Many growers have difficulty in extracting themselves from an occupation that requires their initial, personal expenditure, or debt of hundreds of thousands of dollars. Additionally, many who live in regions or states of broiler growing facilities suffer from gases emitted by these facilities and correspondingly lower property values. Several demographic, economic, education, health, and quality of life metrics were analyzed for the 50 U.S. states to provide insights regarding the ethics of the broiler industry and why some states produce significantly more broilers than others. (shrink)

Bottom of the Pyramid (BOP) strategies recognize for the first time that global companies can contribute to the alleviation of worldwide poverty by adopting non-traditional and mostly non-Western models of business involvement. It is now widely accepted that poverty and hunger arise not because there are no goods or food, but because billions of people lack income to purchase them. It is also a common belief that the private sector can play a significant role in lifting the poor from (...) the margins of the market system. This would require strategic and mindset shifts in global companies leading to a very different path where their operations intersect with the greater good of communities, societies, and nations. Successful engagement in the untapped market space at the base of the global income pyramid calls for completely new capabilities, responsibilities, and values. Alliance building with local and non-traditional partners, promoting bottom-up solutions and understanding social sustainability are some of these new managerial challenges. This article reflects on some of the critical challenges of global companies and global managers in their strategic engagement at the BOP and explores how large firms can become involved in the pursuit of social capital acquisition and how new approaches of public–private partnerships in reformulating the profit-performance links, the downscaling of products or services without compromising their quality and integrity, the bridging of the information and infrastructure gap, educating, and empowering the poor, together with innovations through technological adaptations can be managed through the embracing of new mindsets. A number of frameworks are presented with a view to contributing to the debate and outlining new value objectives for global companies. (shrink)

Two experiments were run to demonstrate the presence of a partial reinforcement extinction effect (PREE) and a partial punishment effect (PPE) 4 weeks after training in a 1-trial/day procedure. In the PREE paradigm, two groups of animals were trained to run a straight alley for food reward; one group was rewarded on every trial (CRF), whereas the other was rewarded on only 50% of the trials (PRF). In the test phase, extinction, no reward was present on any trial. Four (...) weeks after the end of acquisition, and subsequent to 7 days of CRF retraining, PRF animals showed greater resistance to extinction than did their CRF controls. The PPE paradigm resembled the PREE paradigm in all aspects, except that mild electric foot shock, together with the food reward, was used instead of nonreward on 50% of the acquisition trials. In the test phase, all animals were shocked and given a food reward on every trial. Four weeks after the end of acquisition and retraining, the animals with previous experience of shock in acquisition showed greater resistance to punishment than did their controls. (shrink)

Because of their being science-based and because they have sparked off an extended debate on how technologies are conceived and developed, biotechnologies represent a particularly useful point of departure for a more general discussion about the evolution of agricultural techniques, as regards the origin and the distinguishing characteristics of different forms of knowledge and know-how.This article seeks to discuss how “knowledge” from different sources (agricultural, industrial, and scientific) on the one hand, and how the abstract and concrete elements that enter (...) into the knowledge acquisition process, on the other hand, come together and become linked as determinants of different technical paths of development. The growing recourse to biotechnologies tends progressively to modify the common knowledge base mobilized for agro-food production. Even though at present the development of biotechnologies seems to be set in a model of continuity in relation to the current techniques, their full potential could express itself in redefining the relations between Man and Nature, ultimately reconciling the production of agricultural consumer goods and the reproduction of the agro-ecosystems. (shrink)

This dissertation explores issues in the philosophy of psychology and metaphysics through the lens of the emotion of disgust, and its corresponding property, disgustingness. The first chapter organizes an extremely large body of data about disgust, imposes two constraints any theory must meet, and offers a cognitive model of the mechanisms underlying the emotion. The second chapter explores the evolution of disgust, and argues for the Entanglement thesis: this uniquely human emotion was formed when two formerly distinct mechanisms, one dedicated (...) to monitoring food intake and protecting against poisons, the other dedicated to protecting against parasitic infection, where driven together until they became functionally integrated. The third chapter explores the sorts of acquisition mechanisms that could give rise to the patterns of individual and cultural level variation we find with disgust elicitors. It argues for the Empathic Acquisition thesis, which holds that one important route for the social acquisition and transmission of disgust elicitors is linked to empathic recognition of facial expressions of the emotion. The fourth chapter builds on the Entanglement thesis, and embeds the emotion of disgust in gene-culture coevolutionary theory and the tribal instincts hypothesis. The Co-opt thesis is defended, which maintains that disgust was co-opted to play an important role in our moral psychology, particularly in our cognition of social norms and ethnic boundary markers. In doing so, however, it brings to bear many features initially linked to poisons and parasites. This explains the puzzling and troublesome character of moral judgments linked to disgust. After shifting gears from psychology to metaphysics, the fifth chapter recasts the Humean tradition of projectivism in the terminology of cognitive science. Using examples such as disgust, I argue that a psychologized projectivism is able to make sense of the idea that some properties are projected onto the world, rather than found there to begin with. The final chapter criticizes three other accounts of the property of disgustingness, two inspired by functionalism in the philosophy of color, one inspired by fittingness accounts in metaethics. I argue that none provide nearly as satisfactory account of the property as the psychologized projectivism articulated previously. (shrink)

This article considers natural signs and their role in the origin of language. Natural signs, sometimes called primary signs, are connected with their signified by causal relationships, concomitance, or likeliness. And their acquisition is directed by both objective reality and past experience (memory). The discovery and use of natural signs is a required prerequisite of existence for any living systems because they are indispensable to movement, the search for food, regulation, communication, and many other information-related activities. It is (...) argued that the birth of conventional signs, sometimes called secondary signs, was determined by a connotative use of natural signs and that, regulated and maintained by them, human language developed. At the same time, the origin and development of human language presupposes a ‘rational turn’ from the given and external reality of natural signs to the rationally constructed reality of artificial signs and rules that are internally maintained by the subjects’ deliberate activities, and actual and inherited social tradition (social memory). In view of this, language is defined as a dynamic system that must both be natural and artificial, empirical and a priori, inductive and deductive. This bilateral origin and regulation of language is the dual-inference of language. (shrink)