Acceptance of elderly or marginal health individuals as kidney donors is debated, with practices varying between centres. Transplant recipients, live kidney donors and health-care professionals caring for patients with renal failure were surveyed regarding their views on live donor kidney transplantation (LDKT) of marginal health (diabetes, hypertension, atherosclerosis, obesity, etc.) and elderly donors. Participants were recruited within a tertiary renal and transplant centre and invited to participate in focus groups and structured interviews. They also completed an anonymous questionnaire. Of 464 (...) participants who completed the questionnaire (36% health-care professionals and 64% patients), 49% and 64%, respectively, stated that marginal and elderly donors should be accepted for LDKT. In the structured interviews, emphasis was given to presenting to donor, recipient and their respective families a calculated risk regarding the effect that either a nephrectomy or transplant has on long-term quality of life. Participants stated that an independent third party in addition to the transplant team should discuss involved risks. Issues of ‘how desperate’ the recipient's situation is should also be considered. Health-care professionals stated that regardless of the strength of will of an individual to donate a kidney (despite age, health problems or personal risk), they should always have the right to say ‘no’ if performing a specific LDKT was against their professional and ethical values. About half of those surveyed considered that marginal health and elderly donors were acceptable for LDKT. Emphasis was given to the explanation to donors and recipients of the risks involved in such transplantation. (shrink)

Le dualisme de Braïlas (1812–1884) qui fut l’unique partisan de Victor Cousin (1792–1867) à avoir, après lui, constitué un système philosophique complet, est un dualisme modéré, du fait qu’en premier lieu, entre la matière et l’esprit, tout un groupe d’activités de la conscience humaine y est censé s’interpoler; qu’en deuxième lieu, le dogmatisme rationaliste braïlien est fondé sur une correspondance rigoureuse entre l’ordre universel et l’ordre rationnel, qui n’est guère dérangé que par l’intuition d’un ordre supérieur et plus parfait, conçu (...) et reproduit par l’imagination, grâce à des processus créationnels; et qu’en troisième lieu, la philosophie braïlienne, quant à ses caractères dominants, s’avère, surtout du point de vue épistémologique, non pas une application servile, mais, par contre, une considération critique des thèses de l’éclectisme cousinien. (shrink)

Self destruction, inapprehensible an option as it might be, has been a challenging issue for philosophers and scholars since the dawn of time, forcing meditation into a vigorous and everlasting debate. The core question is: could suicide ever be deemed rational a choice? And if so, could it count as a moral alternative, if the circumstances call for it? The Stoics from Zeno up to Epictetus and Seneca regarded suicide as the ultimate resort, as the utmost opportunity for a rational (...) being to maintain his virtue, when all other bridges are burnt. For an act to be moral, it has to be deliberate, as well as the manifestation of an established evaluative hierarchy, however spontaneous and instantaneous might the latter be. In other words, a moral act is one that agents rationally opt for over other possible alternatives, on the subjective basis of their alleged best interests. Modern philosophers as Tom Beauchamp, Margaret Battin and Jacques Choron stress the criterion of rationality as a key issue regarding the ethics of suicide. Utilizing Rorty’s second definition of rationality, the article examines whether self destruction can be the outcome of proper evaluative assessment and deliberation, given that, as T. N. Pelegrinis suggests, such an evaluation seems to rest on a symmetry case, which might hardly be based on sound foundation. (shrink)

This study examines the representation of male and female musicians in world-class symphony orchestras. Personnel of 40 orchestras of three regions, UK, Europe and the USA and distributions of men and women across the four orchestral departments: strings, woodwind, brass and percussion are compared. Significant differences in representation between orchestras of the three regions are reported. Practices adopted by orchestras when appointing musicians to vacant positions are reviewed and numbers of males and females appointed to rank-and-file and Section Principals are (...) compared. Career patterns of male and female musicians are also compared. Increases in numbers of women appointed to orchestral posts in the last three decades are compared with increases in the proportion of women in the general workforce. The data of orchestral membership are then compared with the numbers of young people receiving tuition on orchestral instruments retrieved from a large national database (n = 391,000 students). Implications for the future of male and female representation in orchestral personnel are then considered. (shrink)

Empathy is essential in story comprehension as it requires understanding of the emotions and intentions of the characters. We evaluated the sensitivity of an emotional perspective-taking task using Aesop’s Fables in relation to empathy. Participants (N = 301) were presented with 15 short fables and were asked to rate the intensity of the emotions they would feel (anger, sadness, disgust, fear, surprise, joy, trust, and anticipation) by adopting the perspective of one of the characters (offender, victim) or the observer’s perspective. (...) A data-driven approach revealed that participants’ responses were aligned with the characters’ intentions, suggesting successful emotional perspective-taking. Participants sympathized with the victim rather than the offender, demonstrating affective sharing processes. Further, participants with higher empathy scores exhibited stronger negative emotions from the victim’s perspective, independently of their level of distress. Our task was not influenced by gender effects. We suggest that the Aesop’s Fables task could provide an indirect instrument to study empathy. (shrink)

Explores intellectual and philosophical evolution of German philosopher Martin Heidegger, focusing on period after World War II. Analyzes how Heidegger s ideas, particularly his notion of being, influenced and were influenced by postwar context, including confrontation with Nazism and emergence of new philosophical currents. Argues that Heidegger s work offers relevant insights for contemporary philosophical debates and calls for a critical dialogue with his legacy. Discusses Heidegger s philosophy in the context of French and German philosophical schools, highlighting relevance of (...) his ideas and impact they had on contemporary philosophy. (shrink)

Treatise with auto-commentary on Dvaita philosophy.

Molla Halil’e göre insanların bu dünyada yaptıkları iyiliklere karşılık Yüce Allah onları ahirette lütfuyla nimetlendirecek ve Cennetine koyacaktır. Bu, Allah’ın insanlara bir va‘didir. Allah va‘dinden asla dönmez. Çünkü Allah’ın va‘dinden dönmesi, O’nun hakkında bir eksiklik sayılır. Ancak bu durum O’nun için vucûbiyet ifade etmez. Vucubiyet kavramı çeşitli anlamlarda kullanıldığı için anlam kargaşasına yol açabilir. Buna sebebiyet vermemek için kelamda özellikle de bu makalede “zorunluluk” anlamına kullanılacak olup bazen gereklilik anlamı da ihtiva edebilir. Allah, kötülük yapanları ise adaletiyle cezalandıracaktır. Bu da (...) Allah’ın va‘îdi olup, va‘îdi’nden dönebilir. Bu, O’nun hakkında bir noksanlığa sebebiyet vermez. Çünkü cezalandırmaktan vazgeçmesi Allah’ın merhametinin ve lütfunun bir sonucudur. Bununla birlikte ne va‘d ve ne de va‘îd Allah’a vacip değildir. Molla Halil’e göre, büyük günah insanı imandan çıkarmaz. Mu‘tezile’ye göre büyük günah işleyen kimse dünyada ne mümin olur ne de kâfir ikisinin arasında bir yerde durur. Buna da fasıklık denir. Haricîlere göre ise, ister büyük, isterse küçük olsun, her türlü günah sahibini iman dairesinden çıkarır ve küfür dairesine dahil eder. Molla Halil’e göre, ahiret hayatı ruh ve cesetle birlikte olacaktır. Bu üm-metin günahkârlarına peygamberler, şehitler ve salih kimseler şefaat edecek-tir. Mu‘tezile‘ye göre şefaat sadece iyilerin derecesinin yükselmesi içindir. Günahkârlar için şefaat olmayacaktır. Günahkâr müminler Cehenneme girseler de ebedi kalmayacaklar. Kâfirlerin azapları ise devamlı olacak ve bunlar ebedi olarak Cehennemde kalacaklardır. Biz bu makalede önce sevap ve İkâb kelimelerinin lügat ve ıstılah anlamları üzerinde duracak, sonra bu bağlamda ayet ve hadislerde verilen bilgileri ve bunların açıklamalarını ele alacağız. Daha sonra Molla Halil’in bu konulara dair görüşlerini sunmaya çalışacağız. Onun sevap ve İkâb ile ilgili tanımlarını, bunların sonuçlarına dair yaşanacakları ve varılacak yerleri ele alan yaklaşımlarını sunmaya çalışacağız. Burada farklı görüşlere sahip olmaları nedeniyle çoğunlukla Mu‘tezile’nin ve az da olsa Haricilerin görüşlerine de mukayese oluşturması için değineceğiz. Burada sadece Molla Halil’in görüşlerini değil, onun içinden geldiği Ehli Sünnetin görüşlerini, sünni kaynakları temel alarak aktarmaya çalışacağız. (shrink)

Decision-making capacityDecision-making capacity for pediatric patients can be difficult to determine and is influenced by a myriad of developmental considerations. This chapter begins with a discussion concerning the nature of decision-makingDecision-making and what constitutes competency. The “rule of sevensRule of sevens” frameworkFramework is then used to explicate pertinent developmental milestonesMilestones for children, dividing pediatric developmentDevelopment into 0–7, 7–14, and 14+ years of age. In particular, the authors highlight the most important cognitiveCognitive, socialSocial, andSocial emotionalemotionalEmotional considerations in each of these periods (...) and how they pertain to a child’s ability to make important medical decisions. (shrink)

Following Kit Fine (2007), we can say that the de jure pair represent the referent as the same while the second one does not do so. There are roughly three ways of capturing this difference. One could say that de jure coreference between two expression occurrences happen because (a) the occurrences have identical meanings, (b) they have identical syntactic properties, or (c) they enter into a semantic relation not grounded in identity of meaning or syntax. In what follows, I give (...) some reason to think that de jure coreference is not a transitive relation. As a consequence, we can rule out (a) and (b) just on these grounds alone (since identity is a transitive relation). (c) then looks promising. I argue that this gives further support for a relationist semantics along the lines of what Kit Fine has proposed. (shrink)

Context: Immunity includes cognitive concepts: the organism is thought to specifically recognize foreign materials and develop a memory of these encounters. Vaccines are thought to work by enhancing this immunological memory. Lymphocytes are key cells and specific antibodies are key molecules in immune recognition. Antibodies are blood proteins called “immunoglobulins.” Spontaneously formed immunoglobulins are seen as “natural” antibodies to dietary components and commensal bacteria. Immune cognition is used simply as a didactic metaphor. Problem: Do the cognitive aspects of immunology stem (...) from the activities of cells and molecules, or are they ascribed by the immunologist operating as a human observer? (1) An immense variety of immunoglobulins may bind to the same antigen with different binding energies. It is the immunologist who arbitrates the boundary between those that are specific (and declared antibodies) and those that are not. Specific antibodies serve as functional labels pasted onto natural immunoglobulins, as if they were recognizing elements. Is this “arbitration” the true cognitive event ascribed to immunoglobulins and lymphocytes? (2) A major impasse exists between progress in experimental immunology and its translation into clinical results. A proper understanding of immunological activity demands a wider view of an organism’s biology and, also, of the interference of human observers in delineating experimental realities, such as the specificity of immune recognition. Maturana’s biology of cognition and language provides one such approach. Method: Use of Maturana’s biology of cognition and language concepts to describe immunological activity. Results: A whole new understanding of immunological activity is suggested. Implications: A major change in the way of seeing is proposed that may eventually help the translation of this knowledge into clinical results. Furthermore, the immune system may also become a proper model for cognitive analyses. (shrink)

The article traces the forty-year history of the establishment of the Bioethics training course at the Volgograd State Medical University, which turns 85 this year. It is told about those who played a major role in the development of bioethics as a training course, what difficulties and successes were along this path. The logic of the institutionalization of bioethics through the creation of ethical examination procedures is traced. Actual problems of bioethics, as well as ongoing bioethical activities are not covered (...) and are not called, since the materials of the anniversary issue of the journal are devoted to them. (shrink)

Contributed articles on Jacques Derrida, French philosopher, and his theories of deconstruction and postmoderinsm; includes articles on his perpectives on literature and philosophy.

LIBERTY IN HUME'S HISTORY OF ENGLAND In his own lifetime, Hume was feted by his admirers as a great historian, and even his enemies conceded that he was a controversial historian with whom one had to reckon. On the other hand, Hume failed to achieve positive recognition for his philosophical views. It was Hume's History of England that played an influential role in public policy debate during the eighteenth century in both Great Britain and in the United States. Hume's Hist01Y (...) of England passed through seven editions and was beginning to be perceived as a classic before Hume's death. Voltaire, as an historian, considered it "perhaps the best ever written in any lan guage. " Gibbon greatly admired Hume's work and said, of a letter written by Hume in 1776 praising the Decline and Fall of the Roman Empire, that a compliment from Hume "overpaid the labor of ten years. " After Hume's death on August 20, 1776, the History became a factor in the revolutionary events that began to unfold. Louis XVI was a close student of Hume's History, and his valet records that, upon having learned that the Convention had voted the death penalty, the King asked for the volume in Hume's History covering the trial and execution of Charles I to read in the days that remained. But if Louis XVI found the consolations of philosophical history in the Stuart volumes, Thomas Jefferson saw in them a cause for alarm. (shrink)