Rationale, aims and objectives Given the increasing prevalence of cataract and demand for cataract extraction surgery, patients must often wait to undergo this procedure. We validated a previously developed priority scoring system in terms of clinical variables, pre-intervention health status, appropriateness of surgery and gain in visual acuity (VA) and health-related quality of life (HRQoL).Methods Explicit prioritization criteria for cataract extraction created by a variation of the Research and Development (RAND) and University of California Los Angeles appropriateness methodology were retrospectively (...) applied to a prospective cohort of 5257 patients on waiting lists to undergo cataract by phacoemulsification at 17 hospitals in Spain. Demographic data, clinical data and data related to surgical technique were collected by trained ophthalmologists. Patients were evaluated by their ophthalmologist before the intervention and 6 weeks afterward. They also completed, by mail, the Visual Function Index (VF-14) before the intervention and 3 months afterward.Results High-priority patients experienced greater improvement in VA and HRQoL than those classified as intermediate or low-priority (P < 0.0001), even after adjusting by VA and the VF-14 score at baseline. The time to intervention was the same for high-priority patients as it was for intermediate and low-priority patients.Conclusions The priority score we developed identified patients most likely to experience the greatest improvements from cataract extraction. Use of this tool could provide a fairer and more rational way to prioritize patients for cataract extraction. (shrink)

Providing the first English translation of Análisis del ser del mexicano, this book features a full biography of Uranga, a detailed overview of the translated text, and discussion of Uranga's relevance to contemporary debates in the phenomenology of culture, the philosophy of liberation, Latin American philosophy and phenomenology itself. Reading Uranga's brilliant words expertly translated and introduced by Carlos Alberto Sánchez finally allows us to understand why this Mexican philosopher is considered one of the most fearless and original thinkers of (...) the 20th century. (shrink)

Reichle et al. argue that the mechanism that determines where to fixate the eyes is controlled mostly by low-level processes. Therefore, unlike other competing models (e.g., the SWIFT model), the E-Z Reader model cannot account for “global” regressions as a result of linguistic difficulties. We argue that the model needs to be extended to account for regressive saccades.

En esta investigación se realiza un análisis de las normativas y protocolos autonómicos y locales de las ludotecas pertenecientes a la Comunidad Autónoma de Castilla y León (España) durante los años 2017-2022. Parte de un diseño de mapeo sistemático de normativas con el siguiente criterio de inclusión “localidades de más de 5000 habitantes de la comunidad castellano-leonesa” por entender que estas poseen recursos económicos para mantener en el tiempo estos servicios sociocomunitarios. Se estudian los documentos entre los años 2017 y (...) 2022 con la intención de analizar la evolución de las ludotecas en Castilla y León. (shrink)

Equational reasoning arises in many areas of mathematics and computer science. It is a cornerstone of algebraic reasoning and results essential in tasks of specification and verification in functional programming, where a program is mainly a set of equations. The usual manipulation of identities while conducting informal proofs obviates many intermediate steps that are neccesary while developing them using a formal system, such as the equationally complete Birkhoff calculus ${\mathcal{B}}$. This deductive system does not fit in the common manner of (...) doing mathematical proofs, and it is not compatible with the mechanisms of proof assistants. The aim of this work is to provide a deductive system ${\mathcal{B}}^{\textrm{GOAL}}$ for equality, equivalent to ${\mathcal{B}}$ but suitable for constructing equational proofs in a backward fashion. This feature makes it adequate for interactive proof-search in the approach of proof assistants. This will be achieved by turning ${\mathcal{B}}^{\textrm{GOAL}}$ into a transition system of formal tactics in the style of Edinburgh LCF, such transformation allows us to give a direct formal definition of backward proof in equational logic. (shrink)

Includes articles about Origen, Thomas Aquinas, Hegel, Schleiermacher, Blondel, Teilhard de Chardin, Barth, Heidegger, Gadamer, postmodernism.

First published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.

The parallel distributed processing (PDP) perspective brings forward the important point that all semantic phenomena are based on analog underlying mechanisms, involving the weighted summation of multiple inputs by individual neurons. It falls short of indicating, however, how the essentially discrete nature of semantic processing may emerge at the cognitive level. Bridging this gap probably requires attractor networks.

The aim of this text is to develop an epistemological-technique approach which permit analyze the work of Juan Downey, and his use of technical medias and also include the struggle against the State in the political and cultural model of the primitive societies of the Yano- mani, particularly by the work of Pierre Clastres and Jacques Lizot, and also their point of view of the methods of production in the societies of abundance, as theorized the anthropologist Marshall Sahlins, considering these (...) anthropological paradigms as a medium to understand the mediatic interaction and the technique development in the works of Juan Downey. (shrink)

Post‐translational modifications regulate each step of DNA replication to ensure the faithful transmission of genetic information. In this context, we recently showed that deubiquitination of SUMO2/3 and SUMOylated proteins by USP7 helps to create a SUMO‐rich and ubiquitin‐low environment around replisomes that is necessary to maintain the activity of replication forks and for new origin firing. We propose that a two‐flag system mediates the collective concentration of factors at sites of DNA replication, whereby SUMO and Ubiquitinated‐SUMO would constitute “stay” or (...) “go” signals respectively for replisome and accessory factors. We here discuss the findings that led to this model, which have implications for the potential use of USP7 inhibitors as anticancer agents. (shrink)

El presente artículo realiza una aproximación a la conformación de narrativas culturales,en las que se incluyen representaciones sociales y habitus a partir de cambios enel espacio público urbano y el desarrollo de nuevas formas de relación entre grupose individuos y el espacio urbano. Incluye el análisis desde una visión integradora, alconsiderarlas como representaciones narrativas culturales. Estos estudios permitenacceder a abordajes desde múltiples disciplinas, los cuales contribuyen a la realizaciónde investigaciones más integrales de la relación espacio público urbano-cultura-grupossociales, así como las (...) narrativas que nacen de esta correspondencia. (shrink)

L’évolution industrielle nous destine à vivre dans des environnements technologiques caractérisés par une dissémination informatique totale dans la multitude et d’objets connectés capables de traitement sémantique et d’interaction informationnelle avec les humains. Dans ce contexte d’Intelligence ambiante se déploient des dispositifs domotiques d’Interactions dites naturelles Homme / machine. Ainsi de Google Home présenté comme : « une enceinte à commande vocale qui fonctionne avec l'Assistant Google ». On pourra tout aussi bien discuter avec les agents de la concurrence : Amazon (...) Echo, Apple HomePod, etc. Ces dispositifs nous conduisent à interroger une étape contemporaine majeure de « la révolution technologique du langage » et de son automatisation, qui fait des machines de réels sujets parlants, inscrits dans un « couplage humano-machinique ». Dans ce contexte fortement marqué par les affordances, nous observons les modalités de cette interaction artéfactuelle et dite naturelle, caractérisée notamment par une simulation conversationnelle et une personnalisation des dispositifs technologiques. La perspective est celle d’une linguistique post-dualiste et non logocentrée, dans la lignée du courant de l’analyse du discours : Texte-Discours-Interaction. (shrink)

Analyse de la fonction et caracteristiques de la liaison entre la victoire sportive et le passé ‘mythique’ par l’intermédiaire du lien généalogique avec un dieu et/ou un héros. Examen des exemples suivants: Olympique 2, Isthmique 3, Ol. 6, Ol. 9, Ol. 7, Pythique 4, Pyth. 5, Néméenne 11. La mention généalogique renforce le moment de gloire de la victoire , ajoute parfois une perspective religieuse, génère une dimension spatiale , contribue à l’organisation du poème et devient un recours encomiastique très (...) efficace.Myth and Genealogy in Pindar. An analysis of the function and characteristics of the link between the victory in the games and the ‘mythical’ past, through a genealogical relation­ship with a god and/or hero. An examination of the following poems: Olympian 2, Isthmian 3, Ol. 6, 9 and 7, Pythian 4 and 5, Nemean 11. The genealogical refer­ence reinforces the glory of the victory , adds sometimes a religious perspective, creates a spatial dimension , contributes to the organisation of the poem and becomes a very efficient encomiastic resource. (shrink)

In this paper we explore the absentminded driver problem using two different scenarios. In the first scenario we assume that the driver is capable of reasoning about his degree of absentmindedness before he hits the highway. This leads to a Savage-style model where the states are mutually exclusive and the act-state independence is in place. In the second we employ centred possibilities, by modelling the states (i.e. the events about which the driver is uncertain) as the possible final destinations indexed (...) by a time period. The optimal probability we find for continuing at an exit is different from almost all papers in the literature. In this scenario, act-state independence is still violated, but states are mutually exclusive and the driver arrives at his optimal choice probability via Bayesian updating. We show that our solution is the only one guaranteeing immunity from sure loss via a Dutch strategy, and that – despite initial appearances – it is time consistent. This raises important implications for the rationality of commitment in such scenarios. (shrink)

The act of iudicare hostes (‘declare public enemy’) was a formal pronouncement of the Roman Senate, voted for the first time in 88 BCE following a proposal by L. Cornelius Sulla after his first march on Rome. Legal historians have generally interpreted it as an emergency measure intended to preserve legality in a situation of civil strife and viewed it as a consistently defined institutional framework throughout the final decades of the Republic. Through an analysis of Sulla’s performative political communication, (...) before, during and in the immediate aftermath of the march, this paper argues that the act of judging (iudicare) someone a public enemy (hostis publicus) was first deployed as a political action, void of legal effects. Later instances of iudicare suggest that this act underwent a process of institutionalization after 63 BCE. (shrink)

Se trata de una reseña del libro de Jacques Rancière. Disenso. Ensayos sobre estética y política, primera edición en español. México: Fondo de Cultura Económica, 275 páginas.

Los últimos diez años –prácticamente la década a caballo del año 2000– han sido muy fecundos en la reflexión y en el magisterio eclesial a propósito especialmente de la evangelización, la iniciación cristiana y la catequesis. Muchos documentos, publicaciones y experiencias quieren relanzar la acción evangelizadora y catequética por nuevos derroteros.

Stakeholder engagement and dialogue have a central role in defining the relations between organisations and their internal and external interlocutors. Drawing upon the analysis of dialogic motifs, power–conflict dynamics and sociopolitical perspectives, and based on a set of interviews with the stakeholders of a consumer-owned cooperative, the research explores the dialogic potential of stakeholder engagement. The analysis revealed a fragmented picture where the co-design and co-implementation aspects were mainly related to the non-business areas of cooperative life, while business logic dominated (...) the most central aspects. Stakeholder engagement was mainly related to consensus building, while dialogic engagement based on a pluralistic understanding was only partially considered and then neglected. The social capital in the local area, the growing size of the organisation and the related power structure embrace stakeholder engagement, influencing the orientation of the dialogic dynamic. The analysis indicates that a dialogic exchange is a relative concept which depends on the interests involved and the topics discussed. It also reveals that the key factors in the democratisation of stakeholder engagement are a mutual understanding and long-term opportunities. Common sociopolitical aspects are also important, but they do not necessarily guarantee the creation of dialogism paths. The research contributes to the critical dialogic literature in revealing whether and how stakeholder engagement has been implemented in a specific setting. It also shows the limitations of voluntarist stakeholder engagement initiatives. (shrink)

The ageing society poses significant challenges to Europe’s economy and society. In coming to grips with these issues, we must be aware of their ethical dimensions. Values are the heart of the European Union, as Article 1a of the Lisbon Treaty makes clear: “The Union is founded on the values of respect for human dignity…”. The notion of Europe as a community of values has various important implications, including the development of inclusion policies. A special case of exclusion concerns the (...) gap between those people with effective access to digital and information technology and those without access to it, the “digital divide”, which in Europe is chiefly age-related. Policies to overcome the digital divide and, more generally speaking, e-inclusion policies addressing the ageing population raise some ethical problems. Among younger senior citizens, say those between 65 and 80 years old, the main issues are likely to be universal access to ICT and e-participation. Among the older senior citizens, say those more than 80 years old, the main issues are mental and physical deterioration and assistive technology. An approach geared towards the protection of human rights could match the different needs of senior citizens and provide concrete guidance to evaluate information technologies for them. (shrink)

Se trata de una reseña del libro de Fabiana Erazun y Mariana Castillo Merlo (editoras) (2021) _Pensar la política en clave republicana: Debates sobre igualdad y libertad_, Neuquén, Universidad Nacional del Comahue, 180 páginas.