This paper discusses various problems of explanations by mechanisms. Two positions are distinguished: the narrow position claims that only explanations by mechanisms are acceptable. It is argued that this position leads to an infinite regress because the discovery of a mechanism must entail the search for other mechanisms etc. Another paradoxical consequence of this postulate is that every successful explanation by mechanisms is unsatisfactory because it generates new ``black box'' explanations. The second – liberal – (...) position that is advanced in this paper regards, besides explanations by mechanisms, also the discovery of bivariate correlations as a first step of an explanation by mechanisms as meaningful. It is further argued that there is no contradiction between causal analysis and the explanation by mechanisms. Instead, explanations by mechanisms always presuppose the analysis of causal structures (but not vice versa). The final point is that an explanation by mechanisms is not inconsistent with the Hempel-Oppenheim scheme of explanation. (shrink)

We provide three innovations to recent debates about whether topological or “network” explanations are a species of mechanistic explanation. First, we more precisely characterize the requirement that all topological explanations are mechanistic explanations and show scientific practice to belie such a requirement. Second, we provide an account that unifies mechanistic and non-mechanistic topological explanations, thereby enriching both the mechanist and autonomist programs by highlighting when and where topological explanations are mechanistic. Third, we defend this view against some powerful mechanist (...) objections. We conclude from this that topological explanations are autonomous from their mechanistic counterparts. (shrink)

Traditional accounts of explanation fail to illuminate the explanatory relevance of “models that are descriptively false” in the sense that the regularities they entail fail to obtain. In this paper, I propose an account of explanation, which I call ‘explanation by concretization’, that serves to explicate the explanatory relevance of such models. Starting from a highly abstract and idealized model, causal explanations of the absence of regularities are sought by adding complexity to the model or by concretizing (...) it. Whether this process is successful depends on whether the abstractions and idealizations in the basic model succeed in isolating a mechanism, i.e. in representing how it operates when interfering factors are absent. This account is developed in the context of economics and contrasted to those of Daniel Hausman and Nancy Cartwright. I go on to provide an account of how unrealistic models can be used for providing understanding of the way mechanisms work. (shrink)

The periodic table is one of the best-known systems of classification in science. Because of the information it contains, it raises explanation-seeking questions. Quantum mechanical models of the behaviour of electrons may be seen as providing explanations in response to these questions. In this paper we first address the question ‘Do quantum mechanical models of atoms provide legitimate explanations?’ Because our answer is positive, our next question is ‘Are the explanations provided by quantum mechanical models of atoms mechanistic explanations?’. (...) This question is motivated by the fact that in many scientific disciplines, mechanistic explanations are abundant. Because our answer to the second question is negative, our last question is ‘What kind of explanation do quantum mechanical models of atom provide?’ By addressing these questions, we shed light on the nature of an important type of chemical explanation. (shrink)

This paper discusses the prospect of the "new social history" guided by the recent work of Charles Tilly on the methodology of social and historical explanation. Tilly advocates explanation by mechanisms as the alternative to the covering law explanation. Tilly's proposals are considered to be the attempt to reshape the practices of social and historical explanation following the example set by the explanatory practices of molecular biology, neurobiology, and other recent "success stories" in the life (...) sciences. Recent work in the philosophy of science on these practices by Peter Machamer, Lindley Darden, Carl Craver and others is used as the foil to disclose the difficulties of Tilly's project. Most important among them is the dilemma of specification: if diagrams (standard forms of the representation of mechanisms) are intended as representations of robust causal processes, they cannot be specific enough to provide complete mechanism schemata, and are bound to remain mechanism sketches. If mechanism sketches are elaborated in detail by tracing particular causal processes, they provide representations of fragile causal processes, which cannot be considered as mechanisms comparable to those in advanced life and other special sciences. Tilly's work on the explanation of mechanisms can be considered as symptomatic for the recent trend to visualize the forms of historical representation. As far as diagrams seem to be able to communicate stories in a direct way (without narrative discourse), this trend is a challenge for the theory of historical representation. The new theories of scientific explanation focusing on the explanatory practices of the life sciences can provide examples and be the source of inspiration for the work on the theory of historical and social explanation, going beyond the confines of the received framework of the covering law model of explanation. (shrink)

In this paper I discuss two questions. What does Kant understand by mechanical explanation in the Critique of judgment? And why does he think that mechanical explanation is the only type of the explanation of nature available to us? According to the interpretation proposed, mechanical explanations in the Critique of judgment refer to a particular species of empirical causal laws. Mechanical laws aim to explain nature by reference to the causal interaction between the forces of the parts (...) of matter and the way in which they form into complex material wholes. Just like any other empirical causal law, however, mechanical laws can never be known with full certainty. The conception according to which we can explain all of nature by means of mechanical laws, it turns out, is based on what Kant calls ‘regulative’ or ‘reflective’ considerations about nature. Nothing in Kant’s Critique of judgment suggests that these considerations can ever be justified by reference to how the natural world really is. I suggest that what, upon first consideration, appears to be a thoroughly mechanistic conception of nature in Kant is much more limited than one might have expected. (shrink)

Analogies to machines are commonplace in the life sciences, especially in cellular and molecular biology — they shape conceptions of phenomena and expectations about how they are to be explained. This paper offers a framework for thinking about such analogies. The guiding idea is that machine-like systems are especially amenable to decompositional explanation, i.e., to analyses that tease apart underlying components and attend to their structural features and interrelations. I argue that for decomposition to succeed a system must exhibit (...) causal orderliness, which I explicate in terms of differentiation among parts and the significance of local relations. I also discuss what makes a model depict its target as machine-like, suggesting that a key issue is the degree of detail with respect to the target’s parts and their interrelations. (shrink)

William Whewell’s philosophy of scientific discovery is applied to the problem of understanding the nature of unification and explanation by the composition of causes in Newtonian mechanics. The essay attempts to demonstrate: the sense in which ”approximate’ laws successfully refer to real physical systems rather than to idealizations of them; why good theoretical constructs are not badly underdetermined by observation; and why, in particular, Newtonian forces are not conventional and how empiricist arguments against the existence of component causes, and (...) against the veracity of the fundamental laws, are flawed. (shrink)

Mechanisms are now taken widely in philosophy of science to provide one of modern science’s basic explanatory devices. This has raised lively debate concerning the relationship between mechanisms, laws and explanation. This paper focuses on cases where a mechanism gives rise to a ceteris paribus law, addressing two inter-related questions: What kind of explanation is involved? and What is going on in the world when mechanism M affords behavior B described in a ceteris paribus law? We (...) explore various answers offered by ‘new mechanists’ and others before setting out and explaining our own answers: mechanistic explanations are a species of oldfashioned covering-law explanation and this often accounts in part for their explanatory power; and B is what it takes for some set of principles that govern the features of M’s parts in their arrangement in M all to be instanced together. (shrink)

This paper describes a pattern of explanation prevalent in the biological sciences that I call a ‘lineage explanation’. The aim of these explanations is to make plausible certain trajectories of change through phenotypic space. They do this by laying out a series of stages, where each stage shows how some mechanism worked, and the differences between each adjacent stage demonstrates how one mechanism, through minor modifications, could be changed into another. These explanations are important, for though it is (...) widely accepted that there is an ‘incremental constraint’ on evolutionary change, in an important class of cases it is difficult to see how to satisfy this constraint. I show that lineage explanations answer important questions about evolutionary change, but do so by demonstrating differences between individuals rather than invoking population processes, such as natural selection.1. Introduction2. Turning a ‘Scale’ into a ‘Plume’3. Lineage Explanations in Biology3.1. The evolution of eyes3.2. The evolution of feathers4. The Two Dimensions of a Lineage Explanation4.1. The production dimension4.2. The continuity dimension4.3. The dual role of the parts5. Constraining the Explanations6. Operational and Generative Lineages7. Explaining Change Without Populations8. Conclusion. (shrink)

The book explores several open questions in the philosophy of statistical mechanics. Each chapter is written by a leading expert in the field. Here is a list of some questions that are addressed in the book: 1) Boltzmann showed how the phenomenological gas laws of thermodynamics can be derived from statistical mechanics. Since classical mechanics is a deterministic theory there are no probabilities in it. Since statistical mechanics is based on classical mechanics, all the probabilities statistical mechanics talks about cannot (...) be fundamental. However, if probabilities are epistemic, how can they play a role, as they seem to do, in laws, explanation, and prediction? 2) Many physicists use the notion of typicality instead of the one of probability when discussing statistical mechanics. What is the connection between the two notions? 3) How can one extend Boltzmann’s analysis to the quantum domain, where some theories are indeterministic? 4) Boltzmann’s explanation fundamentally involves cosmology: for the explanation to go through the Big Bang needs to have had extremely low entropy. Does the fact that the Big Bang was a low entropy state imply that it was, in some sense, “highly improbable” and requires an explanation? 5) What exactly is the connection between statistical and classical mechanics? Is the one of theory reduction or there is no such thing? 6) Statistical mechanics has two main formulation: one due to Botzmann and the other due to Gibbs. What is the connection between the two formulations . (shrink)

Mechanistic explanation has an impressive track record of advancing our understanding of complex, hierarchically organized physical systems, particularly biological and neural systems. But not every complex system can be understood mechanistically. Psychological capacities are often understood by providing cognitive models of the systems that underlie them. I argue that these models, while superficially similar to mechanistic models, in fact have a substantially more complex relation to the real underlying system. They are typically constructed using a range of techniques for (...) abstracting the functional properties of the system, which may not coincide with its mechanistic organization. I describe these techniques and show that despite being non-mechanistic, these cognitive models can satisfy the normative constraints on good explanations. (shrink)

At the centre of this study is the theoretical and empirical analysis of action-formation mechanisms in norm-relevant, situations. Basically two mechanisms are employed, namely action according to a) moral principles and b) the principle of deterrence. Conflicting assumptions concerning the way these mechanisms work are deduced from two theoretical perspectives, the high-cost/low-cost. hypothesis and Situational Action Theory (SAT). While the high-cost/low-cost. hypothesis leads to the assumption that, criminal action is explained by the principle of deterrence in high-cost, (...) situations and, in low-cost, situations, by moral principles, it. follows from SAT that., in high-cost, situations, the principle of deterrence has an effect, only on those persons with weak moral principles, and influences of moral principles are expected in low-cost, situations. Empirical analysis of these hypotheses is conducted with the help of data that, have been collected as part, of a mail survey (n=2383) of a disproportionately layered random sample of residents of an East. German city. Data analyses are carried out. in order to estimate the influences of the theoretically specified predictors simultaneously for high-cost, and low-cost, situations with multiple group comparisons. The study’s results partially support, both theoretical perspectives. They are finally discussed with respect, to theoretical and methodological aspects. (shrink)

Besides mechanistic explanations of phenomena, which have been seriously investigated in the last decade, biology and ecology also include explanations that pinpoint specific mathematical properties as explanatory of the explanandum under focus. Among these structural explanations, one finds topological explanations, and recent science pervasively relies on them. This reliance is especially due to the necessity to model large sets of data with no practical possibility to track the proper activities of all the numerous entities. The paper first defines topological explanations (...) and then explains why topological explanations and mechanisms are different in principle. Then it shows that they are pervasive both in the study of networks—whose importance has been increasingly acknowledged at each level of the biological hierarchy—and in contexts where the notion of selective neutrality is crucial; this allows me to capture the difference between mechanisms and topological explanations in terms of practical modelling practices. The rest of the paper investigates how in practice mechanisms and topologies are combined. They may be articulated in theoretical structures and explanatory strategies, first through a relation of constraint, second in interlevel theories, or they may condition each other. Finally, I explore how a particular model can integrate mechanistic informations, by focusing on the recent practice of merging networks in ecology and its consequences upon multiscale modelling. (shrink)

While many studies from analytical sociology apply agent-based modeling to analyze the transformational mechanisms linking the micro to the macro level, we hold the view that both situational and action formation mechanisms can rather be unveiled by means of more advanced quantitative methods. By focusing on selective exposure to quality newspapers, our study has both an analytical and a substantive aim. First., our analytical aim is to amend the psychological mechanism of avoiding cognitive dissonance by social mechanisms (...) allowing postulates on how the selective exposure effect might vary by particular social groups. Second, our substantive aim is to set the ground for a longitudinal analysis of selective exposure to quality papers by placing these social mechanisms in the context of social and cultural change. By referring to hypothetical data, we illustrate which kind of (multilevel) moderator effects would have to hold if our hypotheses were true. (shrink)

This paper investigates the relationship between structural explanation and the New Mechanistic account of explanation. The aim of this paper is twofold: firstly, to argue that some phenomena in the domain of fundamental physics, although mechanically brute, are structurally explained; and secondly, by elaborating on the contrast between SE and mechanistic explanation to better clarify some features of SE. Finally, this paper will argue that, notwithstanding their apparently antithetical character, SE and ME can be reconciled within a (...) unified account of general scientific explanation. (shrink)

The evolutionary maintenance of sexual reproduction is a case of explanatory pluralism of central importance to evolutionary biology. I analyze this pluralism from an epistemological perspective. My thesis is that the various explanations of sex are explanatory by virtue of local factors and hence are importantly distinct from one another and cannot be subsumed under a single unifying framework. A critic may argue that philosophical accounts of mechanism can provide just such a framework. I show that this attempt at unification (...) fails because the accounts of sex are not explanatory simply in light of being their being mechanistic; rather they are explanatory because they are particular kinds of mechanisms. The explanatory power of a mechanism is dependent on its epistemological context and the contexts of these mechanisms differ. (shrink)

Quantum mechanics portrays the universe as involving non-local influences that are difficult to reconcile with relativity theory. By postulating backward causation, retro-causal interpretations of quantum mechanics could circumvent these influences and accordingly reconcile quantum mechanics with relativity. The postulation of backward causation poses various challenges for the retro-causal interpretations of quantum mechanics and for the existing conceptual frameworks for analyzing counterfactual dependence, causation and causal explanation. In this chapter, we analyze the nature of time, causation and explanation in (...) a local, deterministic retro-causal interpretation of quantum mechanics that is inspired by Bohmian mechanics. This interpretation of quantum mechanics offers a deterministic, local ‘hidden-variables’ model of the Einstein-Podolsky-Rosen experiment that poses a new challenge for Reichenbach’s principle of the common cause. In this model, the common cause – the state of particles at the emission from the source – screens off the correlation between its effects – the distant measurement outcomes – but nevertheless fails to explain the correlation between the effects. (shrink)

This article examines the role of experimental generalizations and physical laws in neuroscientific explanations, using Hodgkin and Huxley’s electrophysiological model from 1952 as a test case. I show that the fact that the model was partly fitted to experimental data did not affect its explanatory status, nor did the false mechanistic assumptions made by Hodgkin and Huxley. The model satisfies two important criteria of explanatory status: it contains invariant generalizations and it is modular (both in James Woodward’s sense). Further, I (...) argue that there is a sense in which the explanatory heteronomy thesis holds true for this case. †To contact the author, please write to: SNF‐Professorship for Philosophy of Science, University of Basel, Missionsstrasse 21, 4003 Basel, Switzerland; e‐mail: [email protected]. (shrink)

Henri Poincaré’s views on the foundations of mechanics and the nature of mechanical explanation were influenced by the work of two of the most renowned nineteenth century scientists, James Clerk Maxwell and Heinrich Hertz. In order then to unravel Poincaré’s views and own contribution to the subject it is important to see the connection between Maxwell ’s and Hertz’s researches on the one hand and Poincaré’s on the other. Consequently, I start this paper with a brief account of Poincaré’s (...) encounter with Maxwell ’s work in electromagnetism. Then, in section 2, I move on to show how Hertz’s work on the foundations of mechanics shaped Poincaré own views. In sections 3 and 4, I formulate Poincaré’s own conventionalist philosophy of mechanics and show how several methodological considerations, especially the search for unity, mitigated his conventionalism. Having thus examined Poincaré’s views on the foundations of mechanics, in section 5 I turn my attention to his notion of mechanical explanation and his proof that a mechanical explanation of a set of phenomena is possible if the principle of conservation of energy is satisfied. I then go on to show how Poincaré secured the possibility of a mechanical explanation of electromagnetic phenomena, and also how, having done so, he ended up with an unlimited number of configurations of matter in motion that could underpin electromagnetic phenomena. The upshot of this paper will be that Poincaré departed from the traditional conceptions on mechanical explanation and defended a purely structural conception, the strong point of which was that it promoted — as the motto of this paper says — the true and only aim of science, namely unity. (shrink)

Cartwright et al. in European Journal for Philosophy of Science, 10 and the new mechanists agree that regular behaviors described in cp laws are generated by mechanisms. However, there is disagreement with regard to the two questions that Cartwright at al. ask: the epistemological question and the ontological question. Most importantly, Cartwright et al. argue that the explanation involved is a CL-explanation, while the new mechanists insist that mechanistic explanation and CL-explanation are competitors. In this (...) reply, I will highlight some worries regarding Cartwright et al.’s analysis of the relationship between mechanisms and cp laws and I will provide alternative answers to the two questions in line with the new mechanistic approach. (shrink)

Network neuroscience represents the brain as a collection of regions and inter-regional connections. Given its ability to formalize systems-level models, network neuroscience has generated unique explanations of neural function and behavior. The mechanistic status of these explanations and how they can contribute to and fit within the field of neuroscience as a whole has received careful treatment from philosophers. However, these philosophical contributions have not yet reached many neuroscientists. Here we complement formal philosophical efforts by providing an applied perspective from (...) and for neuroscientists. We discuss the mechanistic status of the explanations offered by network neuroscience and how they contribute to, enhance, and interdigitate with other types of explanations in neuroscience. In doing so, we rely on philosophical work concerning the role of causality, scale, and mechanisms in scientific explanations. In particular, we make the distinction between an explanation and the evidence supporting that explanation, and we argue for a scale-free nature of mechanistic explanations. In the course of these discussions, we hope to provide a useful applied framework in which network neuroscience explanations can be exercised across scales and combined with other fields of neuroscience to gain deeper insights into the brain and behavior. (shrink)

The past two decades have witnessed an increase in interest in social mechanisms and mechanistic explanations of social macro-phenomena. This paper addresses the question of what the components of social mechanisms in mechanistic explanations of social macro-phenomena must be. Analytical sociology’s initial position and the main new proposals by analytical sociologists are discussed. It is argued that all of them are faced with outstanding difficulties. Subsequently, a minimal requirement regarding the components of social mechanisms is introduced. It (...) is held that a component of a social mechanism in a mechanistic explanation of a social macro-phenomenon must not have the explanandum phenomenon as a part of it. (shrink)

Mechanisms are often characterized as causal structures and the interventionist account of causation is then used to characterize what it is to be a causal structure. The associated modularity constraint on causal structures has evoked criticism against using the theory as an account of mechanisms, since many mechanisms seem to violate modularity. This paper answers to this criticism by making a distinction between a causal system and a causal structure. It makes sense to ask what the modularity (...) properties of a given causal structure are, but not whether a causal system is modular tout court. The counter-examples to the interventionist account are systems in which a particular structure is modular in variables, but not in parameters. A failure of parameter-modularity does not by itself threaten the interventionist interpretation of the structure and the possibility of causally explaining with that structure, but it does mean that knowledge of the structure is not sufficient to constitutively explain system-level properties of the embedding system. (shrink)

mechanism" is frequently encountered in the social science literature, but there is considerable confusion about the exact meaning of the term. The article begins by addressing the main conceptual issues. Use of this term is the hallmark of an approach that is critical of the explanatory deficits of correlational analysis and of the covering-law model, advocating instead the causal reconstruction of the processes that account for given macro-phenomena. The term "social mechanisms" should be used to refer to recurrent processes (...) generating a specific kind of outcome. Explanation of social macro-phenomena by mechanisms typically involves causal regression to lower-level elements, as stipulated by methodological individualism. While there exist a good many mechanism models to explain emergent effects of collective behavior, we lack a similarly systematic treatment of generative mechanisms in which institutions and specific kinds of structural configurations play the decisive role. Key Words: causal regression • correlational analysis • emergent effects • micro-macro processes • social mechanisms • structural determinants. (shrink)

Microbes in the gastrointestinal tract are under selective pressure to manipulate host eating behavior to increase their fitness, sometimes at the expense of host fitness. Microbes may do this through two potential strategies: (i) generating cravings for foods that they specialize on or foods that suppress their competitors, or (ii) inducing dysphoria until we eat foods that enhance their fitness. We review several potential mechanisms for microbial control over eating behavior including microbial influence on reward and satiety pathways, production (...) of toxins that alter mood, changes to receptors including taste receptors, and hijacking of the vagus nerve, the neural axis between the gut and the brain. We also review the evidence for alternative explanations for cravings and unhealthy eating behavior. Because microbiota are easily manipulatable by prebiotics, probiotics, antibiotics, fecal transplants, and dietary changes, altering our microbiota offers a tractable approach to otherwise intractable problems of obesity and unhealthy eating. (shrink)

The Scientific Revolution is often associated with a transition to a ``mechanistic'' world view. However, ``mechanization'' is not the term that best captures the distinctive nature of modern physics: ``mathematization'' would be a better characterization. Modern physics attempts to find mathematical relations between quantities, and does not require that these relations be interpreted in terms of mechanisms. Moreover, in modern physics there are cases in which it is unnatural to give the mathematical formalism a mechanistic interpretation, even if ``mechanistic'' (...) is broadly construed. Both on the level of ontology and that of explanation physics turns out to be more general and liberal than what is suggested by the catchphrase that physics explains by identifying mechanisms. Although mechanistic explanation remains an important conceptual tool, in particular for achieving understanding, it is not the only one available and cannot lay claim to fundamentality. (shrink)

The ArgumentThe claim that Jan Swammerdam's empirical research did not support his theory of biological preformation is shown to rest on a notion of evidence narrower than that used by many seventeenth-century natural philosophers. The principles of evidence behind the use of mechanical models are developed. It is then shown that the Cartesian theory of biological reproduction and embryology failed to gain acceptance because it did not meet the evidential requirements of these principles. The problems in this and other mechanistic (...) theories prior to Swammerdam are found to arise from certain difficulties and tensions in the mechanical conception of nature, which Swammerdam's theory is able to resolve. The relation between Swammerdam's empirical research and his theory is examined and shown to satisfy the required notion of evidence.Leibniz' puzzling appeals to Swammerdam's research in support of his metaphysical doctrine of the spontaneous development of individual substances are then examined and shown to fall within the parameters of the notion of evidence. (shrink)

The central aim of this paper is to shed light on the nature of explanation in computational neuroscience. I argue that computational models in this domain possess explanatory force to the extent that they describe the mechanisms responsible for producing a given phenomenon—paralleling how other mechanistic models explain. Conceiving computational explanation as a species of mechanistic explanation affords an important distinction between computational models that play genuine explanatory roles and those that merely provide accurate descriptions or (...) predictions of phenomena. It also serves to clarify the pattern of model refinement and elaboration undertaken by computational neuroscientists. (shrink)

In many domains of biology, explanation takes the form of characterizing the mechanism responsible for a particular phenomenon in a specific biological system. How are such explanations generalized? One important strategy assumes conservation of mechanisms through evolutionary descent. But conservation is seldom complete. In the case discussed, the central mechanism for circadian rhythms in animals was first identified in Drosophila and then extended to mammals. Scientists' working assumption that the clock mechanisms would be conserved both yielded important (...) generalizations and served as a heuristic for discovery, especially when significant differences between the insect and mammalian mechanism were identified. †To contact the author, please write to: Department of Philosophy and Interdisciplinary Programs in Science Studies and Cognitive Science, 0119, University of California, San Diego, La Jolla, CA 92093‐0119; e‐mail: [email protected]. (shrink)

In this piece the author takes issue with Mario Bunge’s claims that conceptual and semiotic systems have "compositions, environments and structures, but no mechanisms." Structures, according to Bunge, can never be mechanisms in conceptual and semiotic systems. Contra this the author argues that in social systems, social structures (which are concept-dependent and reproduced and/or transformed, at least in part, semiotically), can be mechanisms in the sense that such structures are one of the processes in a concrete system (...) that makes itwhat it is. As such, not only may conceptual and semiotic systems have mechanisms, but they may also themselves be considered some of the mechanisms that make the social what it is. As such, they can be said to possess powers and liabilities that neither reside at lower levels nor are explainable in terms of the lower level. To hold out the prospect of social explanation by conceptual and/or semiotic mechanisms does not represent an attempt to decouple these systems from material factors. What it does mean is that conceptual and/or semiotic systems can, potentially at least, play a role in social explanation; and themselves be subject to explanation. Key Words: mechanisms • social • structures • cause • explanation • realism • emergence • reductionism. (shrink)

Explanation in biology has long been characterized as being very different from explanation in other scientific disciplines, very much so from explanation in physics. One of the reasons was the existence in biology of explanation types that were unheard of in the physical sciences: teleological explanations (e.g. Hull 1974), evolutionary explanations (e.g. Mayr 1988), or even functional explanations (e.g. Neander 1991). More recently, and owing much to the rise of molecular biology, biological explanations have been depicted (...) as mechanisms (e.g; Machamer, Darden and Craver 2000). The aim of this volume is to shed some new light on the diversity of explanation types in biology. What are the different types of explanation that occur in biology? Are these types of explanation specific to particular sub-disciplines of biology, or to particular types of problems across biology? How do they relate to each another? Do they compete with one another for answering the same questions? Or do they complement each other, providing insights to different questions? What are the reasons for such diversity? Can this diversity be overcome by a broader unifying model of explanation or is it more profound and irreducible? Why? This volume aims at making sense of this diversity of types of explanations that are found in biology, of their relationship with one another. After all, explanation in biology may prove not only different from explanation in the physical sciences, but also much more diverse than originally anticipated. (shrink)

Causal mechanisms theory has provided an important contribution to the theory of social explanation. This article considers whether CMT also makes a contribution to improvement of social science methodology. Methodology serves as a guide to the construction of research questions and explanatory hypotheses. Research is guided by background assumptions about the ontology of the domain of investigation. CMT provides a valuable ontology for social science research. Furthermore, it provides a valuable research heuristic: “seek out the causal mechanisms (...) that underlie an outcome of interest.” CMT does indeed have valuable implications for social science investigation, hypothesis formation, and research strategy. (shrink)

Is Neo-Aristotelian hylomorphism compatible mechanistic science? In this essay I forge a rapprochement between Neo-Aristotelian hylomorphism and the "new mechanist philosophy" in biology, neuroscience, and psychology by drawing attention to their shared commitments concerning multilevel organization, mechanisms, and teleology. Significantly, the new mechanists endorse organization realism (a touchstone of hylomorphism). Similarly, Neo-Aristotelian hylomorphism is committed to the reality of mechanisms or causal powers that produce, underlie, or maintain the behavior of (i) phenomena that are constituted through the (ii) (...) spatial, temporal, and active organization of their (iii) component entities and (iv) component activities (the four hallmarks of the new mechanist philosophy). In the course of the essay I address potential disagreements between these two positions pertaining to emergence, downward causation, and teleology. I conclude that Neo-Aristotelian hylomorphism should not been seen as fundamentally opposed to mechanisms; rather, hylomorphism provides a rigorous ontological framework that complements the insights of the new mechanist philosophy of biology, neuroscience and psychology. (shrink)

Distinguishing mechanistic components from mere causally relevant background conditions remains a difficulty for mechanistic accounts of explanation. By distinguishing resources from mechanical parts, I argue that we can more effectively draw this boundary. Further, the distinction makes obvious that there are distinctive resource explanations which are not captured by a traditional part-based mechanistic account. While this suggests a straightforward extension of the mechanistic model, I argue that incorporating resources and resource explanations requires moving beyond the purely local account of (...) levels that some mechanists advocate. (shrink)

One way social scientists explain phenomena is by building structural models. These models are explanatory insofar as they manage to perform a recursive decomposition on an initial multivariate probability distribution, which can be interpreted as a mechanism. Explanations in social sciences share important aspects that have been highlighted in the mechanisms literature. Notably, spelling out the functioning the mechanism gives it explanatory power. Thus social scientists should choose the variables to include in the model on the basis of their (...) function in the mechanism. This paper examines the notion of ‘function’ within structural modelling. We argue that ‘functions’ ought to be understood as the theoretical underpinnings of the causes, namely as the role that causes play in the functioning of the mechanism. (shrink)

This paper analyzes Immanuel Kant’s views on mechanical explanation on the basis of Christian Wolff’s idea of scientific demonstration. Kant takes mechanical explanations to explain properties of wholes in terms of their parts. I reconstruct the nature of such explanations by showing how part-whole conceptualizations in Wolff’s logic and metaphysics shape the ideal of a proper and explanatory scientific demonstration. This logico-philosophical background elucidates why Kant construes mechanical explanations as ideal explanations of nature.

Recent extensions of mechanistic explanation into psychology suggest that cognitive models are only explanatory insofar as they map neatly onto, and serve as scaffolding for more detailed neural models. Filling in those neural details is what these accounts take the integration of cognitive psychology and neuroscience to mean, and they take this process to be seamless. Critics of this view have given up on cognitive models possibly explaining mechanistically in the course of arguing for cognitive models having explanatory value (...) independent of how well they align with neural mechanisms. We can have things both ways, however. The problem with seamless integration accounts is their seamlessness, not that they take cognitive models to be mechanistic. A non-componential view of mechanisms allows for cognitive and neural models that cross cut one another, and for cognitive models that don’t decompose into parts. I illustrate the inadequacy of seamless accounts of integration by contrasting how “filter” models of attention in psychology and of sodium channels in neuroscience developed; by questioning whether the mappings generated by neuroimaging subtraction studies achieve integration; and by reinterpreting the evidence for cognitive models of memory having been successfully integrated with neural models. I argue that the integrations we can realistically expect are more partial, patchy, and full of loose threads than the mosaic unity Craver describes. (shrink)

Scientific explanation is an important goal of scientific practise. Philosophers have proposed a striking diversity of seemingly incompatible accounts of explanation, from deductive-nomological to statistical relevance, unification, pragmatic, causal-mechanical, mechanistic, causal intervention, asymptotic, and model-based accounts. In this dissertation I apply two novel methods to reexamine our evidence about scientific explanation in practise and thereby address the fragmentation of philosophical accounts. I start by collecting a data set of 781 articles from one year of the journal Science. (...) Using automated text mining techniques I measure the frequency and distribution of several groups of philosophically interesting words, such as "explain", "cause", "evidence", "theory", "law", "mechanism", and "model". I show that "explain" words are much more common in scientific writing than in other genres, occurring in roughly half of all articles, and that their use is very often qualified or negated. These results about the use of words complement traditional conceptual analysis. Next I use random samples from the data set to develop a large number of small case studies across a wide range of scientific disciplines. I use a sample of "explain" sentences to develop and defend a new general philosophical account of scientific explanation, and then test my account against a larger set of randomly sampled sentences and abstracts. Five coarse categories can classify the explanans and explananda of my cases: data, entities, kinds, models, and theories. The pair of the categories of the explanans and explanandum indicates the "form" of an explanation. The explain-relation supports counterfactual reasoning about the dependence of qualities of the explanandum on qualities of the explanans. But for each form there is a different "core relation" between explanans and explanandum that supports the explain-relation. Causation, modelling, and argument are the core relations for different forms of scientific explanation between different categories of explanans and explananda. This flexibility allows me to resolve some of the fragmentation in the philosophical literature. I provide empirical evidence to show that my general philosophical account successfully describes a wide range of scientific practise across a large number of scientific disciplines. (shrink)

Quantum mechanics gives us reason to think both that the world is indeterministic, and that there are irreducibly statistical laws governing objectively chancy processes. Lewis notes that this raises a two-horned dilemma between two options deemed unacceptable: severely curtail our explanatory practices with respect to macro events, or revise our conception of the essence of chance. He maintains, however, that we can escape this dilemma by making a distinction between ‘plain’ why-questions of the simple form ‘Why did D occur?’ and (...) ‘contrastive’ why-questions of the more complex form ‘Why did E occur rather than E*?’ I will argue that even if a chance event receives a nontrivial explanation, there is still a sense in which it happens for no reason if there is a time prior to its occurrence at which the change of its happening when it does is fixed. (shrink)

Biology and history are often viewed as closely related disciplines, with biology informed by history, especially in its task of charting our evolutionary past. Maximizing the opportunities for cross-fertilization in these two fields requires an accurate reckoning of their commonalities and differences-precisely what this volume sets out to achieve. Specially commissioned essays by a team of recognized international researchers cover the full panoply of topics in these fields and include notable contributions on the correlativity of evolutionary and historical explanations, applying (...) to history the latest causal-mechanical approach in the philosophy of biology, and the question of generalized laws that might pertain across the two subjects. The collection opens with a vital interrogation of general issues on explanation that apart from potentially fruitful areas of interaction (could the etiology of the causal-mechanical perspective in biology account for the historical trajectory of the Roman Empire?) this volume also seeks to chart relative certainties distinguishing explanations in biology and history. It also assesses techniques such as the use of probabilities in biological reconstruction, deployed to overcome the inevitable gaps in physical evidence on early evolution. Methodologies such as causal graphs and semantic explanation receive in-depth analysis. Contributions from a host of prominent and widely read philosophers ensure that this new volume has the stature of a major addition to the literature. (shrink)

The philosophy of mechanisms has developed rapidly during the last 30 years. As mechanisms-based explanations (MBEs) are often seen as an alternative to nomological, law-based explanations, MBEs could be relevant in IS. We begin by offering a short history of mechanistic philosophy and set out to clarify the contemporary landscape. We then suggest that mechanistic models provide an alternative to variance and process models in IS. Finally, we highlight how MBEs typically contain deliberate misrepresentations. Although MBEs have recently (...) been advocated as critical realist (CR) accounts in IS, idealizations (deliberate misrepresentations) seem to violate some fundamental tenets of CR and research method principles for CR. Idealizations in MBEs, therefore, may risk being regarded as flawed in IS. If it turns out that CR cannot account for idealizations, naturalism can, and it does so without extra-philosophical baggage. (shrink)

Quantum mechanics has recently indicated that temporal order is not always fixed, a finding that has far-reaching philosophical and theological implications. The phenomena, termed “indefinite causal order,” shows that events can be in a superposition with regard to their order. In the experimental setting with which this article is concerned, two events, A and B, were shown to be in the ordering relations “A before B” and “B before A” at the same time. This article introduces an ongoing project that (...) seeks to make sense of this result, with a particular focus on the methodology by which this research will be undertaken. Specific research questions, particularly regarding what indefinite causal order might mean for the metaphysics of time and the doctrine of salvation, are introduced. The collaborative approach detailed brings together the disciplinary skills of a working scientist and a working theologian. What is offered is a collaborative methodology for interaction between science and religion that is more than the sum of its parts. Alister McGrath’s idea of multiple rationalities is employed as an epistemological framework within which this research takes place. Within an epistemologically pluralistic model, collaborative efforts are not only encouraged but necessary. Complex reality requires an equally complex, usually interdisciplinary, explanation. I argue that such dialogue is both theologically justified and culturally valuable and indicates the direction in which this research will be taken. (shrink)

The aim of this dissertation is to provide an analysis of central concepts in philosophy of science from the perspective of current molecular and developmental research. Each chapter explores the ways in which particular phenomena or discoveries in molecular biology influences our philosophical understanding of the nature of scientific knowledge. The introductory prologue draws some general connections between the various threads, which revolve around two central themes: causation and explanation. Chapter Two identifies a particular type of causal relation which (...) is widespread across the sciences, but cannot be straightforwardly accommodated by extant accounts of causation and causal explanation. Chapter Three explores how the form of redundant causality identified in the previous chapter plays an important role in causal explanation, by making the effect stable and robust. Chapter Four offers a novel perspective on the debate over biological reductionism by distinguishing between different paradigms of molecular explanation. Chapter Five provides a philosophical analysis of the so-called "Developmental Synthesis" of evolutionary and developmental biology, and suggests a general account of scientific unification grounded in the notion of explanatory relevance. Chapter Six offers an account of dispositional properties inspired by mechanisms of gene regulation, according to which dispositions are not properties of entities, but properties that describe the behavior of abstract idealized models. Finally, Chapter Seven scrutinizes the concept of the molecular ecosystem, a metaphor frequently employed by biologists to describe cellular interactions, but seldom articulated in detail. (shrink)

In this paper (which is, at best, a work in progress), I discuss different modes of scientific explanation identified by philosophers (Hempel, Salmon, Kitcher, Friedman, Hughes) and examine how well or badly they capture the "explanations" of phenomena that modern quantum theory provides. I tentatively conclude that quantum explanation is best seen as "structural explanation", and spell out in detail how this works in the case of explaining vacuum correlations. Problems and prospects for structural explanation in (...) quantum theory are also discussed. (shrink)

How do scientific explanations for beliefs affect people's confidence that those beliefs are true? For example, do people think neuroscience-based explanations for belief in God support or challenge God's existence? In five experiments, we find that people tend to think explanations for beliefs corroborate those beliefs if the explanations invoke normally-functioning mechanisms, but not if they invoke abnormal functioning (where “normality” is a matter of proper functioning). This emerges across a variety of kinds of scientific explanations and beliefs (religious, (...) moral, and scientific). We also find evidence that these effects can interact with people's prior beliefs to produce motivated judgments. (shrink)

In this chapter, I sketch the history of mechanistic models of the mental, as related to the technological project of trying to build mechanical minds, and discuss the contemporary debates on psychological and cognitive explanations. In the first section, I introduce the Cartesian notion of mechanism, which has shaped the debate in the centuries to follow. Early mechanistic proposals are also connected with early attempts to formulate the computational account of thinking and reasoning, upheld notably by Hobbes and Leibniz. In (...) the second section, associationist and behaviorist models of the mind are sketched, along with attempts to understand the neural system in terms of connections and associations. Early robotic models, built mostly by behaviorists and other students of animal behavior, are also introduced. In the third section, the focus is on early computational and cybernetic models of the mind. In the fourth section, I deal with computational models of mental mechanisms as proposed by students of artificial intelligence and cognitive science. Then, I sketch the contemporary debate over the question whether computational and psychological models are best understood as offering functional, or maybe mechanistic explanations. (shrink)

The idea at the core of the New Mechanical account of explanation can be summarized in the claim that explaining means showing ‘how things work’. This simple motto hints at three basic features of Mechanistic Explanation (ME): ME is an explanation-how, that implies the description of the processes underlying the phenomenon to be explained and of the entities that engage in such processes. These three elements trace a fundamental contrast with the view inherited from Hume and later (...) from strict logical empiricism (see Creath 2017), focused on epistemic and formal features of science and according to which issues concerning the kind of entities and processes that lie within a theory’s domain are extraneous to science and belong instead to ontology or metaphysics. Philosophers belonging to the new mechanical philosophy believe that the received view of scientific explanation (Hempel 2001), pivoting on the notion of law of nature, overshadows this insight. Since its origin in the 17th century, mechanical philosophy aimed to explain natural phenomena by reducing them to mechanisms. Traditional attempts to define the concept of mechanism involved the identification of a limited set of fundamental elements as, for instance, contact action, action at a distance, inertial motion (see e.g. Hesse 2005), and, more recently, transmission of a mark, or of a conserved quantity (see Frisch, this volume). The new mechanical philosophy rejects this austere characterization of mechanisms and mechanistic explanation and aim at providing a novel, philosophically rigorous explication of the concept of mechanism and of its role in scientific explanation and practice. ME has been adopted with profit in philosophy of special sciences (for instance in biomedical sciences, e.g. in the explanation of chemical transmission at synapses ((Machamer, Darden and Craver 2000), MDC henceforth); but also in social sciences, e.g. the three kinds of social mechanisms in Coleman’s analysis of Max Weber’s account of the role of the Protestant ethic in the growth of capitalism (Hedström and Swedberg 1998)), where exceptionless regularities are rarely ever found. In physics, it is generally possible to formulate explanations in law-based form, with the result that the plurality of explanatory forms might be overlooked. This should not come as a surprise, given that physics was the main inspiration for logical empiricists, and, in particular, Newtonian physics was a template for Hempel’s formulation of the covering law model. However, this situation is unfortunate, since, we will argue, knowing how things work is often part of the explanation of physical phenomena. In this chapter, we provide an introduction to the basic features of ME, with specific focus on its application to physics (section 1). The main part of the chapter is devoted to the defence of two theses: on the one hand, some domains of physics are not compatible with mechanistic reasoning and explanation (section 2); on the other hand, a comprehensive account of explanation in physics can’t dispense with ME (section 3). (shrink)

This paper argues that besides mechanistic explanations, there is a kind of explanation that relies upon “topological” properties of systems in order to derive the explanandum as a consequence, and which does not consider mechanisms or causal processes. I first investigate topological explanations in the case of ecological research on the stability of ecosystems. Then I contrast them with mechanistic explanations, thereby distinguishing the kind of realization they involve from the realization relations entailed by mechanistic explanations, and explain (...) how both kinds of explanations may be articulated in practice. The second section, expanding on the case of ecological stability, considers the phenomenon of robustness at all levels of the biological hierarchy in order to show that topological explanations are indeed pervasive there. Reasons are suggested for this, in which “neutral network” explanations are singled out as a form of topological explanation that spans across many levels. Finally, I appeal to the distinction of explanatory regimes to cast light on a controversy in philosophy of biology, the issue of contingence in evolution, which is shown to essentially involve issues about realization. (shrink)