The place of religion in society has changed profoundly in the last few centuries, particularly in the West. In what will be a defining book for our time, Taylor takes up the question of what these changes mean, and what, precisely, happens when a society becomes one in which faith is only one human possibility among others.

Darwin discusses why different muscles are brought into action under different emotions and how particular animals have adapted for association with man.

v. 1-2. Principles of philosophy and Elements of logic.--v. 3-4. Exact logic (published papers) and The simplest mathematics.--v. 5-6. Pragmatism and pragmaticism and Scientific metaphysics.--v. 7. Science and philosophy.--v. 8. Reviews, correspondence and bibliography.

A new understanding of political philosophy from one of its leading thinkers What is political philosophy? What are its fundamental problems? And how should it be distinguished from moral philosophy? In this book, Charles Larmore redefines the distinctive aims of political philosophy, reformulating in this light the basis of a liberal understanding of politics. Because political life is characterized by deep and enduring conflict between rival interests and differing moral ideals, the core problems of political philosophy are the regulation (...) of conflict and the conditions under which the members of society may thus be made subject to political authority. We cannot assume that reason will lead to unanimity about these matters because individuals hold different moral convictions. Larmore therefore analyzes the concept of reasonable disagreement and investigates the ways we can adjudicate conflicts among people who reasonably disagree about the nature of the human good and the proper basis of political society. Challenging both the classical liberalism of Locke, Kant, and Mill, and more recent theories of political realism proposed by Bernard Williams and others, Larmore argues for a version of political liberalism that is centered on political legitimacy rather than on social justice, and that aims to be well suited to our times rather than universally valid. Forceful and thorough yet concise, What Is Political Philosophy? proposes a new definition of political philosophy and demonstrates the profound implications of that definition. The result is a compelling and distinctive intervention from a major political philosopher. (shrink)

A book on the problems of ethics from the perspective of language and meaning.

In The Autonomy of Morality Charles Larmore challenges two ideas that have shaped the modern mind. The world, he argues, is not a realm of value-neutral fact, nor does human freedom consist in imposing principles of our own devising on an alien reality. Rather, reason consists in being responsive to reasons for thought and action that arise from the world itself. Larmore shows that the moral good has an authority that speaks for itself. Only in this light does the (...) true basis of a liberal political order come into view, as well as the role of unexpected goods in the makeup of a life lived well. (shrink)

I argue that ‘conspiracy theory’ and ‘conspiracy theorist’ as commonly employed are ‘tonkish’ terms (as defined by Arthur Prior and Michael Dummett), licensing inferences from truths to falsehoods; indeed, that they are mega-tonkish terms, since their use is governed by different and competing sets of introduction and elimination rules, delivering different and inconsistent results. Thus ‘conspiracy theory’ and ‘conspiracy theorist’ do not have determinate extensions, which means that generalizations about conspiracy theories or conspiracy theorists do not have determinate truth-values. Hence (...) conspiracy theory theory – psychological or social scientific research into conspiracy theorists and what is wrong with them – is often about as intellectually respectable as an enquiry into bastards and what makes them so mean. (shrink)

Recent arguments concerning the nature of causation in evolutionary theory, now often known as the debate between the 'causalist' and 'statisticalist' positions, have involved answers to a variety of independent questions – definitions of key evolutionary concepts like natural selection, fitness, and genetic drift; causation in multi-level systems; or the nature of evolutionary explanations, among others. This Element offers a way to disentangle one set of these questions surrounding the causal structure of natural selection. Doing so allows us to clearly (...) reconstruct the approach that some of these major competing interpretations of evolutionary theory have to this causal structure, highlighting particular features of philosophical interest within each. Further, those features concern problems not exclusive to the philosophy of biology. Connections between them and, in two case studies, contemporary metaphysics and philosophy of physics demonstrate the potential value of broader collaboration in the understanding of evolution. (shrink)

Charles Crittenden here offers an original solution to one of the traditional dilemmas of philosophy—whether there can be any thing not existing, since to say that some thing does not exist seems to presuppose its existence. Drawing on the tools of Wittgensteinian philosophy and speech act theory, Crittenden argues that we can and often do make reference to unreal objects such as fictional characters, though they do not exist in any sense at all.

Despite its importance, the linkage between genetic and cultural evolution has until now been little explored. An understanding of this linkage is needed to extend evolutionary theory so that it can deal for the first time with the phenomena of mind and human social history. We characterize the process of gene-culture coevolution, in which culture is shaped by biological imperatives while biological traits are simultaneously altered by genetic evolution in response to cultural history. A case is made from both theory (...) and evidence that genetic and cultural evolution are inseverable, and that the human mind has tended to evolve so as to bias individuals toward certain patterns of cognition and choice rather than others. With the aid of mathematical models we trace the coevolutionary circuit: The genes prescribe structure in developmental pathways that lay down endocrine and neural systems, imposing regularities in the development of cognition and behavior; these regularities translate upward into holistic patterns of culture, which can be predicted in the form of probability density distributions ; natural selection acts within human history to favor certain epigenetic rules over others; and the selection alters the frequencies of the underlying genes. The effects of genetic and cultural changes reverberate throughout the circuit and are consequently tested with the passage of each life cycle. In addition to modeling gene-culture coevolution, we apply methods from island biogeography and information theory to examine the cultural capacity of the genes, the factors determining the magnitude of cultural diversity, and the possible reasons for the uniqueness of the human achievement. (shrink)

Will brain imaging technology soon enable neuroscientists to read minds? We cannot answer this question without some understanding of the state of the art in neuroimaging. But neither can we answer this question without some understanding of the concept invoked by the term "mind reading." This article is an attempt to develop such understanding. Our analysis proceeds in two stages. In the first stage, we provide a categorical explication of mind reading. The categorical explication articulates empirical conditions that must be (...) satisfied if mind reading is to be achieved. In the second stage, we develop a metric for judging the proficiency of mind reading experiments. The conception of mind reading that emerges helps to reconcile folk psychological judgments about what mind reading must involve with the constraints imposed by empirical strategies for achieving it. (shrink)

This is the first book-length study of Philo, the principal philosophical teacher of Cicero. Charles Brittain reconstructs the Platonic Academy's gradual rejection of scepticism under Philo's leadership, which prepared the way for the revival of Platonism in the first century AD. The Appendix contains a full collection of the testimonia and 'fragments' of Philo.

The Rise of Chance in Evolutionary Theory: A Pompous Parade of Arithmetic explores a pivotal conceptual moment in the history of evolutionary theory: the development of its extensive reliance on a wide array of concepts of chance. It tells the history of a methodological and conceptual development that reshaped our approach to natural selection over a century, ranging from Darwin’s earliest notebooks in the 1830s to the early years of the Modern Synthesis in the 1930s. Far from being a “pompous (...) parade of arithmetic,” as one early critic argued, evolution transformed during this period to make these conceptual and technical tools indispensable. This book charts the role of chance in evolutionary theory from its beginnings to the earliest days of modern evolutionary theory, making it an ideal resource for evolutionary biologists, historians, philosophers, and researchers in science studies or biological statistics. (shrink)

One potentially extremely fruitful use of the tools of corpus analysis in the philosophy of science is to help us understand disputed terrains within the sciences that we study. For philosophers of biology, for instance, few controversies are as heated as those over the concepts we use in taxonomy to classify the living world, with the definition of ‘species’ perhaps most fundamental among them. As many understandings of biodiversity, in turn, involve counting the number of species present in a given (...) area, these taxonomic concepts thus become crucially implicated in our efforts in conservation biology and our response to climate change. In this chapter, we present a corpus of taxonomic journal papers, and illustrate how it might be used to make progress in the history and philosophy of taxonomy. What parts of the biological world do taxonomists most often study? Are these areas of focus related to other methodological commitments, or perhaps to their underlying conceptual disagreement? Are species that are more important to conservation, or economic concerns, or more important to local cultures, more or less likely to be the target of biological study? Corpus-based methods, we argue, are uniquely powerful for approaching questions such as these, and we hope that the case we present can serve as a fruitful example for others considering their implementation. (shrink)

Anti-racist debate today remains polarised between ‘class reductionist’ (any attempt to address racial disparities reinforces capitalist class relations) and ‘liberal identity’ (disparities in racial representation can be resolved without questioning class inequality) politics. Both positions share a common perspective – racial oppression and class exploitation are the products of distinctive social dynamics whose relationship is historically contingent. This essay is an initial step toward characterising a structurally necessary relationship between capitalism and racial oppression. The essay draws upon Anwar Shaikh and (...) Howard Botwinick’s elaboration of Marx’s political economy, and Ellen Wood’s analysis of the specificity of capitalist imperialism. (shrink)

Antisemitism is fun. This essay explains why and proposes a new approach to combating it.

-/- For all that digital methods—including network visualization, text analysis, and others—have begun to show extensive promise in philosophical contexts, a tension remains between two uses of those tools that have often been taken to be incompatible, or at least to engage in a kind of trade-off: the discovery of new hypotheses and the testing of already-formulated positions. This paper presents this basic distinction, then explores ways to resolve this tension with the help of two interdisciplinary case studies, taken from (...) preregistration in contemporary science and the debate over whig history in the history of science. These case studies, the paper argues, refocus our attention from a mutually exclusive testing/discovery binary to the relationship between our background data or philosophical views and the empirical generalizations that we might draw from the data. Finally, it develops a set of three challenges for philosophers and corresponding avenues for future work that will, it is hoped, allow us to better justify our use of these methods. (shrink)

Hume describes his own “open, social, and cheerful humour” as “a turn of mind which it is more happy to possess, than to be born to an estate of ten thousand a year.” Why does he value a cheerful character so highly? I argue that, for Hume, cheerfulness has two aspects—one manifests as mirth in social situations, and the other as steadfastness against life’s misfortunes. This second aspect is of special interest to Hume in that it safeguards the other virtues. (...) And its connection with the first aspect helps explain how it differs from Stoic tranquility. For Hume, I argue, philosophy has a modest role in promoting human happiness by preserving cheerfulness. (shrink)

Substantially increased wealth inequality across the developed world has prompted many philosophers, economists and legal theorists to support comprehensive taxes on all forms of wealth. Proposals include levying taxes on the basis of total wealth, or alternatively the change in the value of capital holdings measured from year-to-year. This contrasts with most existing policies that tax capital assets at the point they are transferred from one beneficiary to another through sale or gifts. Are these tax reforms likely to meet their (...) aims of greater economic and political equality? We argue that these policies are likely to fail because, following neoclassical economic theory, they are based on a conception of capital as possessing given values in what amounts to a static equilibrium. This mischaracterizes the dynamic and subjective character of market economies and the contested value of real instantiations of capital goods. This makes them very difficult, often impossible, to value apart from at the point of voluntary transfer or profit realization. This means most taxes levied on a mark-to-market basis will be arbitrary and unfair. We propose alternative policies based on an income realization approach to taxation that are more likely to curb excessive wealth holdings. This includes introducing international treaties that prohibit preferential tax treatment for individual companies and specific sectors, and broadening the income tax base to include the imputed rent of personal housing wealth. (shrink)

Philosophers of science often make reference — whether tacitly or explicitly — to the notion of a scientific community. Sometimes, such references are useful to make our object of analysis tractable in the philosophy of science. For others, tracking or understanding particular features of the development of science proves to be tied to notions of a scientific community either as a target of theoretical or social intervention. We argue that the structure of contemporary scientific research poses two unappreciated, or at (...) least underappreciated, challenges to this concept of the “scientific community” in the philosophy of science. In particular, we will present two case studies from robotics research, broadly construed, which show that (1) the boundedness of the scientific community is threatened when private citizens can develop scientific and technological advances at minimal expense (democratization), and (2) the discreteness of scientific research programs is threatened by the complexly interrelated environment of contemporary scientific work (interconnectivity). Taken together, the extent of democratization and interconnectivity present a significant challenge for any practically oriented philosophy of science, one which we hope will be taken on directly by philosophers in the future. (shrink)

Within quantum chemistry, the electron clouds that surround nuclei in atoms and molecules are sometimes treated as clouds of probability and sometimes as clouds of charge. These two roles, tracing back to Schrödinger and Born, are in tension with one another but are not incompatible. Schrödinger’s idea that the nucleus of an atom is surrounded by a spread-out electron charge density is supported by a variety of evidence from quantum chemistry, including two methods that are used to determine atomic and (...) molecular structure: the Hartree-Fock method and density functional theory. Taking this evidence as a clue to the foundations of quantum physics, Schrödinger’s electron charge density can be incorporated into many different interpretations of quantum mechanics. (shrink)

In this book, Charles Larmore develops an account of morality, freedom, and reason that rejects the naturalistic metaphysics shaping much of modern thought. Reason, Larmore argues, is responsiveness to reasons, and reasons themselves are essentially normative in character, consisting in the way that physical and psychological facts - facts about the world of nature - count in favor of possibilities of thought and action that we can take up. Moral judgments are true or false in virtue of the moral (...) reasons there are. We need therefore a more comprehensive metaphysics that recognizes a normative dimension to reality as well. Though taking its point of departure in the analysis of moral judgment, this book branches widely into related topics such as freedom and the causal order of the world, textual interpretation, the nature of the self, self-knowledge, and the concept of duties to ourselves. (shrink)

Literary narratology has rightly devoted much attention to analysing the source(s) of verbal information about the story world, usually discussed under the label “narration”, and to any agent(s) that present(s) non-verbalized perspectives on it, usually discussed under the label “focalization”. Assessing the identity of narrators and focalizers is crucial for understanding what is going on in the story world. Which narrative agent is in charge? Is the narration and/or focalization layered? If the latter, is there any “colouring” by the higher-level (...) narrative agent of anything said, thought, or experienced by the lower-level agent? Is the information provided trustworthy? Nuanced? Prejudiced? Narration and focalization have supra-medial as well as medium-specific dimensions. Over the past years, the issue of how these concepts function in the medium of comics, which combines visuals and language, has begun to be systematically addressed. This paper aims to show how the visual mode can, on its own or combined with the written-language mode, signal the sources of narration, focalization, and joint narration-and-focalization, as well as distinguish between different levels at which these take place. (shrink)

Nietzsche's writing style is designed to elicit affective responses in his readers. Humour is one of the most common means by which he attempts to engage his readers' affects. In this article, I explain how and why Nietzsche uses humour to achieve his philosophical ends. The article has three parts. In part 1, I reject interpretations of Nietzsche's humour on which he engages in self‐parody in order to mitigate the charge of decadence or dogmatism by undermining his own philosophical authority. (...) In part 2, I look at how Nietzsche uses humour and laughter as a critical tool in his polemic against traditional morality. I argue that one important way in which Nietzsche uses humour is as a vehicle for enhancing the effectiveness of his ad hominem arguments. In part 3, I show how Nietzsche exploits humour's social dimension in order to find and cultivate what he sees as the right kinds of readers for his works. (shrink)

“This book deals with the main ideas of four American philosophers: Charles Sanders Peirce, William James, John Dewey, and George Herbert Mead. It is based directly upon a study of their writings, from which extensive quotations are made. Its emphasis is upon the ideas themselves and their interrelationships. For this reason the book is not primarily a history of American pragmatic philosophy nor an interpretation of its relation to American culture nor a compendium of scholarly research about this philosophy. (...) All of these matters do enter into the argument, but in a secondary way.”- Publisher. (shrink)

Due to G-7 countries' commitment to sustaining United Nations Sustainable Development Goal 8, which focuses on sustainable economic growth, there is a need to investigate the impact of tax revenue and institutional quality on economic growth, considering the role of artificial intelligence (AI) in the G-7 countries from 2012 to 2022. Cross-Sectional Augmented Autoregressive Distributed Lag (CS-ARDL) technique is used to analyze the data. The study's findings indicate a long-run equilibrium relationship among the variables under examination. The causality results can (...) be categorized as bidirectional, unidirectional, or indicating no causality. Based on the CS-ARDL results, the study recommends that G-7 governments and policymakers prioritize and strengthen the integration of AI into their institutions to stimulate growth in both the short- and long-term. However, the study cautions against overlooking the interaction between AI and tax revenue, as it did not demonstrate support for economic growth. While the interaction between AI and institutional quality shows potential for contributing to growth, it is crucial to implement robust measures to mitigate any potential negative effects that may arise from AI's interaction with tax systems. Therefore, the study suggests the development of AI-friendly tax policies within the G-7 countries, considering the nascent nature of the AI sector/industry. (shrink)

Friendship, in its nature, purpose, and effects, has been an important concern of philosophy since antiquity. It was of particular significance in the life of Gilles Deleuze, one of the most original and influential philosophers of the late twentieth century. Taking L'Abécédaire de Gilles Deleuze -- an eight-hour video interview that was intended to be aired only after Deleuze's death -- as a key source, Charles J. Stivale examines the role of friendship as it appears in Deleuze's work and (...) life. Stivale develops a zigzag methodology practiced by Deleuze himself to explore several concepts as they relate to friendship and to discern how friendship shifts, slips, and creates movement between Deleuze and specific friends. The first section of this study discusses the elements of creativity, pedagogy, and literature that appear implicitly and explicitly in his work. The second section focuses on Deleuze's friendships with Foucault, Derrida, Claire Parnet, and Félix Guattari and reveals his conception of friendship as an ultimately impersonal form of intensity that goes beyond personal relationships. Stivale's analysis offers an intimate view into the thought of one of the greatest thinkers of our time. (shrink)

Embodied, embedded, enactive, and extended theorists do not typically focus on the ontological frameworks in which they develop their theories. One exception is 4E theories that embrace New Mechanism. In this paper, we endorse the New Mechanist’s general turn to ontology, but argue that their ontology is not the best on the market for 4E theories. Instead, we advocate for a different ontology: causal powers realism. Causal powers realism posits that psychological manifestations are the product of mental powers, and that (...) mental powers are empirically-discoverable features of individuals that account for the causal work those individuals do. We contend that causal powers realism provides a unifying framework for the central commitments of 4E theories, as well as additional resources for theorizing in a 4E framework. And while New Mechanism offers some of these resources as well, we argue that causal powers realism is ultimately the better of the two. (shrink)

Research on metaphor has over the past decades increasingly been extended to its visual and multimodal varieties. While analysts of verbal metaphors are helped by the fact that languages have grammars and vocabularies, researchers of visual and multimodal metaphors need to rely on other methods for identification and interpretation. One approach that claims to have developed a robust method for analyzing metaphor in moving images is FILMIP, which has hitherto focused on the specific genre of commercials. In this paper it (...) is argued that there are serious problems with FILMIP. First, the theoretical basis of FILMIP and two empirical studies drawing on it are discussed. Subsequently, its limited use for analyzing metaphors in the genre of feature films is demonstrated on the basis of four case studies. The paper ends with sketching some general advice pertaining to researching metaphor in film, and provides a cautious alternative to FILMIP. (shrink)

This article compares treatments of the Stern–Gerlach experiment across different physical theories, building up to a novel analysis of electron spin measurement in the context of classical Dirac field theory. Modeling the electron as a classical rigid body or point particle, we can explain why the entire electron is always found at just one location on the detector but we cannot explain why there are only two locations where the electron is ever found. Using non-relativistic or relativistic quantum mechanics, we (...) can explain both uniqueness and discreteness. Moving to more fundamental physics, both features can be explained within a quantum theory of the Dirac field. In a classical theory of the Dirac field, the rotating charge of the electron can split into two pieces that each hit the detector at a different location. In this classical context, we can explain a feature of electron spin that is often described as distinctively quantum but we cannot explain another feature that could be explained within any of the other theories. (shrink)

This essay argues that Knafo and Teschke fundamentally misread Brenner’s original contribution to the transition debate. They equate his rejection of trans-historical or trans-modal laws of motion with the notion that social-property relations do not have strong rules of reproduction that structure the actions of agents and give rise to ‘developmental patterns’ specific to each form of social labour. Knafo and Teschke’s critique of Brenner’s analysis of capitalist expansion and crisis is also theoretically and empirically questionable.

In this article, we ask why is it that sociology has been slow to take up the animal challenge, and ask what would happen if it did. We argue that sociology’s fraught relationship with biology, its assumptions about human exceptionalism and its emergence in the context of industrialization and urbanization are key to understanding its lack of attention to animals and contribute to a limited conceptualization of society. This can be remedied by viewing non-human animals as involuntarily embedded in social (...) relationships, a move which involves a redefinition of the social and of what it means to be human; a revision of notions of agency, subjectivity and reflexivity; and a rejection of the speciesism and anthropocentrism on which sociology is based. Finally, the article contends that a full understanding of society is not possible if we continue to direct the sociology gaze only at humans. (shrink)

There seems to be a view that intuitionists not only take the Axiom of Choice (AC) to be true, but also believe it a consequence of their fundamental posits. Widespread or not, this view is largely mistaken. This article offers a brief, yet comprehensive, overview of the status of AC in various intuitionistic and constructivist systems. The survey makes it clear that the Axiom of Choice fails to be a theorem in most contexts and is even outright false in some (...) important contexts. Of the systems surveyed, only intensional type theory renders AC a theorem, but the extent of AC in that theory does not include, for instance, real analysis. Only a small amount of extensionality is required in order for the obvious proof an intuitionist might offer for AC to break down. (shrink)

Volume 32, Issue 6, December 2024, Page 1476-1485.

First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

In this paper, we describe causal powers realism as a conjunction of four claims: causal powers are not reducible to counterfactuals; they are empirically-discoverable; they manifest effects in conjunction with partners; and their manifestations empower further manifestations. We describe four challenges to extended mind theory and for each show how an ontology of causal powers realism either avoids or dissolves the problem. We close by suggesting that causal powers realism isn’t a competitor with extended mind theory but rather a new (...) way to understand what it means for minds to be extended. (shrink)

This volume contains a facsimile reprint of the 1883 Boston edition of Studies in Logic by Members of the Johns Hopkins University, edited by Charles S. Peirce. In relation to this work there are three mutually related aspects of Peirce’s thought which deserve to be particularly emphasized: the community structure of science as propagated and practiced by Peirce; his consideration of the fundamental relationship between logic and semiotics; and his emphatic plea for a historisation of science and, hence, of (...) semiotics. Peirce’s Studies in Logic is preceded in this volume by a portrait of Peirce as scientist, mathematician, historian, logician and philosopher by Max. H. Fisch, and a history of semiotics and Charles S. Peirce by Achim Eschbach. (shrink)

Este estudo busca elucidar de maneira geral o conceito de interseccionalidade e examinar como o paradigma discursivo de Jürgen Habermas desenvolvido em obras como Teoria da ação comunicativa e Facticidade e validade enfrenta a questão das demandas interseccionais por igualdade de tratamento nas sociedades democráticas contemporâneas. O conceito de interseccionalidade chama a atenção para as interrelações e os efeitos colaterais da pertença à diferentes tipos de discriminação social como sexo, raça, gênero, classe social, etnia,entre outros. Habermas reconhece a dimensão interseccional (...) das discriminações em Facticidade e validade, por causa disso, parece fazer todo sentido a questão se o paradigma discursivo possui recursos para enfrentar os obstáculos ao exercício da igualdade social resultantes das desvantagens interseccionais. Há até mesmo quem defenda, como Nancy Fraser, que o conceito de esfera pública burguesa habermasiano, embora ainda bastante promissor, precisa sofrer algumas reformulações para incluir públicos alternativos e prestar contas às demandas sociais geralmente ignoradas pelo público oficial baseado apenas em interesses generalizáveis e considerar os obstáculos enfrentados para uma participação significativa na esfera pública e pela concepção de democracia deliberativa de Habermas. (shrink)

This article defends the thesis that in theorizing about the mind we need to accord first-person (“introspective” or “reflective”) judgments about experience a “selective provisional trust.” Such an approach can form part of a descriptive psychology. It is here so employed to evaluate some influential interpretations of research on attention to conclude that—despite what conventional wisdom suggests—an “introspection-positive” policy actually offers us a better critical perspective than its contrary. What supposedly teaches us the worthlessness of introspection actually shows us why (...) we need to take it seriously. (shrink)

In earlier work I wrestled with the question of the “ontological status” of organisms. It proved difficult to come to a clear decision, because there are many candidates for what such a status is or would be and of course many definitions of what organisms are. But what happens when we turn to theoretical projects “about” organisms that fall under the heading “organicist”? I first suggest that organicist projects have a problem: a combination of invoking Kant, or at least a (...) Kantian “regulative ideal,” usually presented as the epistemological component (or alternately, the complete overall vision) of a vision of organism – as instantiating natural purposes, as a type of “wholeWhole, wholes” distinct from a merely mechanistically specifiable set of parts, etc. – and a more ontological statement about the inherent or essential features of organisms, typically presented according to a combination of a “list of heroes” or “laundry list” of properties of organisms. This amounts to a category mistake. Other problems concern the too-strict oppositions between mechanism and organi(ci)sm, and symmetrical tendencies to “ontologize” (thus objectifying) properties of organisms and to “subjectify” them (turning them into philosophies of subjectivity). I don’t mean to suggest that no one should be an organicist or that Kant is a name that should be banished from civilized society. Rather, to borrow awkwardly from Sade, “organicists, one more effort!” if one wants a naturalistic, non-foundationalist concept of organicism, which is indeed quite active in recent theoretical biology, and which arguably was already alive in the organismic and even vitalist theories of thinkers like Goldstein and Canguilhem. (shrink)

The COVID-19 pandemic touched off an unprecedented search for vaccines and treatments. Without question, the development of vaccines to prevent COVID-19 was an enormous scientific accomplishment. Further, the RECOVERY and Solidarity trials identified effective treatments for COVID-19. But all was not success. The urgent need for COVID-19 prevention and treatment fueled an embrace of risks—to research participants and to the reliability of the science itself—as allegedly necessary costs to speed scientific progress. Scientists and (even) ethicists supported overturning longstanding norms protecting (...) healthy volunteers in human challenge trials to speed vaccine development, but these trials led to no vaccines. Physicians, with the approval of research ethics committees, designed hundreds of unblinded, single-center clinical trials at high risk of bias to speed the identification of new treatments. But these clinical trials led to no treatments. The lesson for future pandemics is that the acceptance of greater risks to participants or science does not reliably lead to progress. We are better served by science that upholds the highest ethical and methodological standards. (shrink)

" -- Dr. Daniel Gardner, Cornell University Medical College Charles Stevens, a prominent neurobiologist who originally trained as a biophysicist (with George Uhlenbeck and Mark Kac), wrote this book almost by accident.

Numbers are symbols manipulated in accord with the axioms of arithmetic. They sometimes represent discrete and continuous quantities, but they are often simply names. Brains, including insect brains, represent the rational numbers with a fixed-point data type, consisting of a significand and an exponent, thereby conveying both magnitude and precision.