The choroid plexuses (CPs) are involved in the most-basic aspects of neural function including maintaining the extracellular milieu of the brain by actively modulating chemical exchange between the CSF and brain parenchyma, surveying the chemical and immunological status of the brain, detoxifying the brain, secreting a nutritive “cocktail” of polypeptides and participating in repair processes following trauma. This diversity of functions may mean that even modest changes in the CP can have far-reaching effects. Indeed, changes in the anatomy and physiology (...) of the CP have been linked to aging and several CNS diseases. It is also possible that replacing diseased or transplanting healthy CP might be useful for treating acute and chronic brain diseases. This review focuses on the wide-ranging and under-appreciated functions of the CP, alterations of these functions in aging and neurodegeneration, and recent demonstrations of the therapeutic potential of transplanted CP for neural trauma. BioEssays 27:262–274, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

Cesario's analysis has three key flaws. First, the focus on whether an effect is “real” overlooks the importance of theory testing. Second, obsession with effects sidelines theoretically informed questions about when and why an effect may arise. Third, failure to take stock of cultural and historical context strips findings of meaning.

This essay aims to reconstruct and defend Pascal’s account of divine hiddenness. In the first section I explain Pascal’s view that divine hiddenness is primarily a function of human volitional aversion and only secondarily a result of God’s intentional action. In the following section I evaluate the primary sense of hiddenness by considering Pascal’s response to the objection that divine goodness requires and divine power makes possible God’s provision of evidence sufficient to overcome human volitional indisposition. While Pascal does think (...) it possible for God to provide such evidence, he argues that this would unjustly harm human freedom and endanger human intellectual understanding. I conclude by addressing a weaker form of the objection through consideration of the second sense of divine hiddenness and Pascal’s surprising view that God’s intentional “hiding” is in fact a progressively deeper entry into the particulars of human history. (shrink)

The name of Pavel Ivanovich Novgorodtsev is not very widely known to the reader at large. It has only been in the last ten or twelve years that isolated studies of particular problems in his creative works have begun to appear.

The study of orders as a product of spiritual creativity has its long and rich history. In addition to ethnographers, religious scholars, psychologists, philosophers, as well as scientists who carried out their research on the brink of several sciences - M. Bachtin, J. Frezer, K. Levy Briul, worked on their analysis. The orders helped find the keys to the style of thinking of primitive tribes, the peculiarities of their worldview, language, remedies, regulation of social relations.

В книге дается структурный анализ различий монотеистических и политических религий и обозначаются перспективы развития новейшего религиозного мировоззрения.

Книга выходит к 150-летию со дня смерти первого русского культуролога А. С. Хомякова, актуализации наследия которого посвящены многолетние авторские исследования.

SummaryThis article proposes to clarify the problem of interpreting Lesniewski's ontology. A distinction is made between two kinds of interpretation: substitutional and “natural”. Substitutional interpretation is shown to involve difficulties and limitations. A “natural” ontology, the major principles of which are presented here, is shown to be of considerable interest.

In this book, the extend to which we can equip artificial agents with moral reasoning capacity is investigated. Attempting to create artificial agents with moral reasoning capabilities challenges our understanding of morality and moral reasoning to its utmost. It also helps philosophers dealing with the inherent complexity of modern organizations. Modern society with large multi-national organizations and extensive information infrastructures provides a backdrop for moral theories that is hard to encompass through mere theorising. Computerized support for theorising is needed to (...) be able to fully grasp and address the inherent complexity. Using moral reasoning capacity will help us addressing the challenges that technological artefacts pose. They do not only contain information about us, they start to act on our behalves.With the increasing autonomy comes an increased need to ensure that their behaviour is in line with what we expect from them. To investigate and address these issues a laboratoy for philosophy is outlined: SophoLab. It consists of a methodology; a framework of modal logic, DEAL; and multi-agent software systems. SophoLab provides the basis for an experimental, computational philosophy. Its viability and usefulness are demonstrated through several experiments. (shrink)

The article characterizes post-folklore as a cultural phenomenon of the network society and defines various aspects of its functioning − sociocommunicative, cultural and psychological. The research methodology consisted of a set of basic approaches, principles and methods of scientific research. To achieve the goal, a set of general scientific and special methods was used, including the methods of logical analysis, problemchronological, generalization, synthesis, induction, and analogy.Research results. It has been proven that post-folkloric creativity is important for the development of social (...) communications, as it promotes the exchange of information between users of social networks, conveys people’s knowledge, moods, feelings, and emotions. In the cultural aspect, the works of post-folklore appear as cultural heritage of modern urbanized society and are represented by various types and genres. From the point of view of psychology, post-folklore has an impact on individual and social consciousness, on the development of cognitive processes, etc. The emergence of post-folklore in the field of education is separately mentioned, which indicates its important importance for the formation of the worldview of school youth.Conclusions. Today post-folklore is the subject of scientific research as a phenomenon of mass culture and network society, as a means of social communication, as a phenomenon that has an impact on public and individual consciousness and is gradually being established in the field of education. In the era of accelerated development of information and communication technologies, everyone has the opportunity to become a collector or author of post-folkloric creativity. Further research is planned to be carried out in the direction of studying the prospects for the development of post-folklore in Ukrainian and foreign cultures. (shrink)

Книга адресована психологам, участвующим в разработке и продвижении инновационных проектов, а также всем тем, кто по роду деятельности имеет отношение к организации инновационных сред в образовании, бизнесе и т.д.

Whereas feminist theory has revitalized our understanding of the culture of medieval Europe, gay theory has only recently begun to review and rewrite that period of our past. Simon Gaunt, writing in 1992, offered several explanations for this state of affairs—including the homophobia of many educational institutions and a notable lack of visible gay scholars in the field. But the following explanation, I think, goes deepest, and is historically the most intractable. However much medieval women may have differed from modern (...) women, he reminds us, they are “clearly and prominently visible within [medieval] systems of representation.” Though we need to reconstruct their experience with care, since most of the records were produced by men, there is nonetheless no shortage of material. Not so for men whose desire was stirred by other men: “one of the prime difficulties in conducting research on the experience of gay people in the Middle Ages is simply lack of data. With whose experience do we identify?”. (shrink)