Béatrice Longuenesse presents an original exploration of our understanding of ourselves and the way we talk about ourselves. In the first part of the book she discusses contemporary analyses of our use of 'I' in language and thought, and compares them to Kant's account of self-consciousness, especially the type of self-consciousness expressed in the proposition 'I think.' According to many contemporary philosophers, necessarily, any instance of our use of 'I' is backed by our consciousness of our own body. For (...) Kant, in contrast, 'I think' just expresses our consciousness of being engaged in bringing rational unity into the contents of our mental states. In the second part of the book, Longuenesse analyzes the details of Kant's view and argues that contemporary discussions in philosophy and psychology stand to benefit from Kant's insights into self-consciousness and the unity of consciousness. The third and final part of the book outlines similarities between Kant's view of the structure of mental life grounding our uses of 'I' in 'I think' and in the moral 'I ought to, ' on the one hand; and Freud's analysis of the organizations of mental processes he calls 'ego' and 'superego' on the other hand. Longuenesse argues that Freudian metapsychology offers a path to a naturalization of Kant's transcendental view of the mind. It offers a developmental account of the normative capacities that ground our uses of 'I, ' which Kant thought could not be accounted for without appealing to a world of pure intelligences, distinct from the empirical, natural world of physical entities. (shrink)

In the Statesman Plato resourced to the paradigm of the art of weaving to define the technique that the good governor must possess. However, with this analogy Plato equated political activity with the most characteristic of women’s activities in Ancient Greece. In such a way, Plato recognized that the philosopher-king, as he had put forward in the Republic , should give way to an expert that, like women weaving, knows the technique to weave the social fabric well. However, Plato did (...) nothing more than propose a model that had already been put in Lysistrata’s mouth by Aristophanes, when ironically postulating a government headed by women, who had no match in the art of weaving. (shrink)

"Kant and the Capacity to Judge" will prove to be an important and influential event in Kant studies and in philosophy.

Der Forschung gelaufig ist die Rede von einer ersten (5./4. Jh. v. Chr.) und der sog. Zweiten Sophistik (2. Jh. n. Chr). Aber auch die Literatur des Hellenismus und der fruhen Kaiserzeit kennt zahlreiche Sophisten. Der Sophist, verstanden als (schlechter) Lehrer und Redner, Gegenspieler des Philosophen oder Vertreter der griechischen Bildung, bildet deshalb den Dreh-und Angelpunkt der Beitrage, die Schlaglichter auf Orte, Methoden und Personen der Bildungsvermittlung werfen. Die Beitrage zeigen, wie pagane und judische Denker, Platoniker und Stoiker Bildung als (...) Weg zum richtigen Welt- und Gottesverstandnis verstehen. Mit Beitragen von: Christian Fron, Marco Galli, Johann Goeken, Stefanie Holder, Alexandra Michalewski, Peter Scholz, Paul Schubert, Gregory E. Sterling, Werner Urbanz, Beatrice Wys. (shrink)

Whenever the state of a biological system is not determined solely by present conditions but depends on its past history, we can say that the system has memory. Bacteria and bacteriophage use a variety of memory mechanisms, some of which seem to convey adaptive value. A genetic type of heritable memory is the programmed inversion of specific DNA sequences, which causes switching between alternative patterns of gene expression. Heritable memory can also be based on epigenetic circuits, in which a system (...) with two possible steady states is locked in one or the other state by a positive feedback loop. Epigenetic states have been observed in a variety of cellular processes, and are maintained by diverse mechanisms. Some of these involve alternative DNA methylation patterns that are stably transmitted to daughter molecules and can affect DNA–protein interactions (e.g., gene transcription). Other mechanisms exploit autocatalytic loops whereby proteins establish the proper conditions for their continued synthesis. Template polymers other than nucleic acids (e.g., components of the cell wall) may also propagate epigenetic states. Non‐heritable memory is exemplified by parasitic organisms that bear a signature of their previous host, such as host‐controlled modification of phage DNA or porin hitchhiking in predatory bacteria. The heterogeneous nature of the examples known may be indicative of widespread occurrence of memory mechanisms in bacteria and phage. However, the actual extent, variety and potential selective value of prokaryotic memory devices remain open questions, still to be addressed experimentally. BioEssays 24:512–518, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

Cell‐wall‐less bacterial variants, or L‐forms, have been described in many bacterial species under laboratory conditions, in infected eukaryotic cell cultures and inside animals. Of special interest for human health is the formation of L‐forms as a consequence of specific antibiotic treatments, and the potential involvement of L‐forms in persistent and relapsing infections. An old enigma about L‐forms is how they can divide in the absence of cell wall synthesis, since septum formation is an essential requisite for cell division. However, the (...) classical definition of L‐forms as cell‐wall‐less bacterial variants may need a revision to accomodate recent observations by Richard d'Ari and coworkers:1 genetic and biochemical evidence indicates that E. coli L‐forms induced by β‐lactam antibiotics do contain small amounts of peptidoglycan, essential for their growth and probably required for septum formation. If these observations are extrapolated to all known L‐forms, the very concept of cell‐wall‐less bacteria may need revision, and be restricted to mycoplasmas and their relatives. BioEssays 29:1189–1191, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

En este artículo exponemos las intuiciones del teólogo y biólogo alemán Karl Schmitz-Moormann sobre la evolución. Como leitmotiv subyacente en toda su obra, Schmitz-Moormann tiene a Teilhard de Chardin. Inspirado por Teilhard y su metafísica de la unión, introduce un nuevo concepto, a saber, la uni-totalidad. Veremos aquí cómo Schmitz-Moormann observa diversas uni-totalidades a lo largo del progreso evolutivo, desde las partículas subatómicas hasta las agrupaciones humanas. Esas diversas uni-totalidades implican, a la vez, diversidad de unión, que puede ser explicada (...) por causas que van desde la interacción nuclear hasta el amor interpersonal. Análogamente, Schmitz-Moormann ve nuestro Dios tri-uno como la Uni-totalidad suprema unida por amor, a la que se acercan las uni-totalidades creadas. (shrink)

Medical science is advancing all the time. Researchers are constantly trying to find new ways to help people to have long and healthy lives. Thanks to their work, doctors today can cure diseases, lessen pain, replace unhealthy limbs or organs, and help infertile couples have children. Doctors can even keep seriously ill people alive against all odds. But not everyone is enamored with advances in medicine. They question whether it is appropriate to prolong life in all cases, or believe that (...) certain treatments have been developed unethically. This book looks at how the ways that doctors treat the sick are developed, and examines some of the questions that are raised by advances in medical science. (shrink)

Hegel's Science of Logic has received less attention than his Phenomenology of Spirit, but Hegel himself took it to be his highest philosophical achievement and the backbone of his system. The present book focuses on this most difficult of Hegel’s published works. Béatrice Longuenesse offers a close analysis of core issues, including discussions of what Hegel means by ‘dialectical logic’, the role and meaning of ‘contradiction’ in Hegel’s philosophy, and Hegel’s justification for the provocative statement that ‘what is actual (...) is rational, what is rational is actual’. She examines both Hegel's debt and his polemical reaction to Kant, and shows in great detail how his project of a ‘dialectical’ logic can be understood only in light of its relation to Kant’s ‘transcendental’ logic. This book will appeal to anyone interested in Hegel's philosophy and its influence on contemporary philosophical discussion. (shrink)

En este artículo queremos profundizar en los datos científicos que hay en la actualidad sobre el Homo neanderthalensis para poder dilucidar, desde las dimensiones biológica, antropológica, anatómica, fisiológica y, finalmente, teológica, la posibilidad de que los neandertales pudieran tener alguna forma de espiritualidad o religiosidad. Si bien, Dios Creador, movido por su voluntad salvífica universal, quiso establecer, por gracia, una relación con todos los seres humanos desde sus orígenes, mostramos en este trabajo que los neandertales, esos homínidos contemporáneos de los (...) primeros humanos anatómicamente modernos (Homo sapiens), a partir de su capacidad intelectual, abstractiva y simbólica, podían tener –y tenían– ya un comportamiento religioso primitivo y rudimentario. Aunque no fueran aún capaces de la revelación divina explícita, estaban en camino hacia la capacidad trascendente. Así que el origen temporal de esa relación humano-divina (además de la dependencia de la Creación) y del don de la gracia debe situarse más allá de los 200.000 años. (shrink)

Le présent essai tente de tirer au clair les différentes significations des termes « conscient » et « conscience » dans la philosophie critique de Kant et en particulier dans la Critique de la raison pure. On considère d’abord les divers types de représentations et ce que veut dire Kant lorsqu’il les dit « avec » ou « sans » conscience. On considère ensuite le concept de conscience tel qu’il apparaît dans la Déduction transcendantale des catégories, où il ne réfère (...) pas à une qualité de représentations particulières, mais à une attitude active de l’esprit. Considérée dans son ensemble, la conception kantienne de la « conscience » mêle inséparablement un aspect que nous appelons, après T. Nagel, « conscience phénoménale », et un aspect proche de la « conscience d’accès » selon N. Block, dans lequel cependant la conscience de soi, exprimable par la proposition « Je pense », joue un rôle central. Cette combinaison fait de Kant un interlocuteur unique dans les débats contemporains sur la conscience et son rôle dans notre vie mentale, ainsi que sur l’IA et sa signification pour l’avenir de l’humanité. (shrink)

Podríamos calificar a Nietzsche de un profeta heroico e innovador, que hace un oráculo de la decadencia, denunciando el triunfo de lo suprasensible, de lo ideal, la imposición de otro mundo como la historia de un error, de una ilusión, fuente común de todas las ficciones, prejuicios y dogmatismos de la tradición cultural occidental. Sin embargo, el pensamiento que Nietzsche expresa con la muerte de dios, y que conlleva el fin del cristianismo y de la metafísica, tiene un origen metafísico (...) y un origen genuinamente cristiano. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Many philosophers as well as many biological psychologists think that recent experiments in neuropsychology have definitively discredited any notion of freedom of the will. I argue that the arguments mounted against the concept of freedom of the will in the name of natural causal determinism are valuable but not new, and that they leave intact a concept of freedom of the will that is compatible with causal determinism. After explaining this concept, I argue that it is interestingly related to our (...) use of the first person pronoun “I.” I discuss three examples of our use of “I” in thought and language and submit a few questions I would like neuropsychologists to answer concerning the brain processes that might underlie those uses. I suggest answering these questions would support the compatibilist notion of freedom of the will I have offered in part 1 of the paper. (shrink)

In this post‐sequencing era, geneticists can focus on functional genomics on a much larger scale than ever before. One goal is the discovery and elucidation of the intricate genetic networks that co‐ordinate transcriptional activation in different regulatory circuitries. High‐throughput gene expression measurement using DNA arrays has thus become routine strategy. This approach, however, does not directly identify gene loci that belong to the same regulatory group; e.g., those that are bound by a common (set of) transcription factor(s). Working in yeast, (...) two groups have recently published an elegant method that could circumvent this problem, by combining chromatin immunoprecipitation and DNA microarrays.(1,2) The method is likely to provide a powerful tool for the dissection of global regulatory networks in eukaryotic cells. BioEssays 23:473–476, 2001. © 2001 John Wiley & Sons, Inc. (shrink)