Incidental research findings, as defined in this symposium’s consensus paper, are unexpected findings discovered in the course of research but “beyond the aims of the study.” These include findings generated by research methodology, such as imaging or genetic analysis, findings related to clinical screening for inclusion or exclusion, or direct observations of physical abnormalities or behavior. Decisions about managing incidental research findings involve important ethical considerations regarding a researcher’s obligations to provide care, minimize harms, and respect research participants’ wishes. When (...) the research participant is a child, the triadic relationship between the researcher, child participant, and parent makes these considerations more complicated. (shrink)

The classic modern statement of mind-body interactionism. In Carpenter's view, not only is mental activity the direct result of the physiological activity of the nervous system, the course of neural activity can in its turn be influenced by the occurrence of mental events.

In _Death in Documentaries: The Memento Mori Experience_, Benjamin Bennett-Carpenter suggests that documentaries are an especially apt form of contemporary _memento mori_; that is, documentaries offer transformative experiences for a viewer to renew one’s consciousness of mortality.

This book provides a philosophical analysis of the notion of selfhood that underlies identity politics. It offers a unique theory of the self that combines previous scholarly work on recognition and the phenomenology of space. The politics of identity occupy the centre of a contested terrain. Marginalised and oppressed peoples continue to seek the transformation of our shared social world and our political institutions required for their lives to be liveable. Public criticism and academic treatments of identity politics often take (...) a disparaging view that treats it as subordinate to more general political questions about justice and the organisation of society and its institutions. This book argues that these polemics ignore the numerous ways in which all politics is concerned with matters of selfhood and identity. Through a rereading of Hegel's account of recognition as an ongoing and dynamic process that constitutes the self, it presents selves-and the categories of identity that qualify these selves-as fundamentally conditioned by the environments in which they appear before themselves and others. It also argues that we do the work of identity in public spaces-particularly digital spaces-and that these spaces shape what identities we can assume and what those identities mean. Contemporary social media technologies facilitate the production of particular forms of selfhood through the combined logics of the interface, the profile, and the post. The Politics of Recognition in the Age of Digital Spaces will be of interest to scholars and advanced students working in a wide range of disciplines including political philosophy, phenomenology, philosophy of technology, sociology, political theory, and critical theory. It will also appeal to anyone with an interest in contemporary identity politics, whether as a matter of study or lived experience. (shrink)

When people use the phrase “personal relationship with Jesus,” how does one explain its significance? Normally attributed to evangelical Protestant Christians, use of the phrase “personal relationship with Jesus” is a complicated phenomenon, and an explanation of it requires drawing upon resources from across multiple disciplines rather than a single discipline only. Attempts to explain exactly what the phrase “personal relationship with Jesus” means frequently can be mystifying, on the one hand, or dismissive and simplistic, on the other hand. This (...) article moves potentially toward a better context for understanding use of the phrase “personal relationship with Jesus” by drawing upon insights from multiple disciplines, including rhetorical and cultural-historical studies, evolutionary and cognitive psychology, and biological/behavioral and social/anthropological studies in order to set forth some basic lines of explanation for use of the phrase “personal relationship with Jesus.” The article concludes with some possible testable statements for future empirical studies. (shrink)

In the nineteenth century, farmers, doctors, and the wider public shared a family of questions and anxieties concerning heredity. Questions over whether injuries, mutilations, and bad habits could be transmitted to offspring had existed for centuries, but found renewed urgency in the popular and practical scientific press from the 1820s onwards. Sometimes referred to as “Lamarckism” or “the inheritance of acquired characteristics,” the potential for transmitting both desirable and disastrous traits to offspring was one of the most pressing scientific questions (...) of the nineteenth century. As I argue in this paper, Carpenter’s religious commitments to abolition and the temperance movement shaped his understanding of heredity. But this also committed him to a body of evidence for the inheritance of acquired characteristics that was coming under criticism for being untrustworthy. Carpenter used his popular treatises on physiology to promote these older, familiar ideas about heredity because they provided vital means of arguing for the unity of mankind and the hereditary dangers of intemperance. While early nineteenth century physiology has been seen by some historians as a challenge to religious authority, given its potentially materialist accounts of the body and the actions of the soul, this paper demonstrates how the missionary and institutional activities of the Unitarian church were ideologically supported by Carpenter’s publications. (shrink)

ABSTRACTBenjamin Vaughan had a passion for anonymity. This is the first attempt to provide a full list of his many and significant contributions to intellectual life and letters in the last quarter of the eighteenth century. No attempt has been made to unveil Vaughan’s scientific writings, and only two of his productions after emigrating to the United States are here included, in both cases because they relate to his earlier writings. After coming to the United States, Vaughan renounced further involvement (...) in the affairs of Europe. (shrink)

ABSTRACTBenjamin Vaughan had a passion for anonymity and Kenneth E. Carpenter’s is the first attempt to provide a full list of his many and significant contributions to intellectual life and letters in the last quarter of the eighteenth century, up to his emigration to North America in 1797. This is an introduction to Carpenter’s important research.

DIALETICS AT A STANDSTILL: BENJAMIN'S "DENKBILDER":0Benjamin's Thougt-Images in Einbahnstraße - Gustan Asselbergs; 0Sichtlich sich verbergend: Die Autor-Figur des Passagen-Werks - Wolfram Malte Fues; 0LIMINAL FIGURES: CHILD AND FLANEUR:0The Child at the Threshold: Walter Benjamin's Berliner Kindheit um 1900 - Corina Stan; 0The Flâneur and the Socio-Economic Critique - Nassima Sahraoui; 0UNSIGHTLY FIGURES: 0Walter Benjamin's Figures of De-Figuration: The Barbarian, the Destructive Character, and the Monster - Sami R. Khatib; 0ANGELS AND HISTORIANS: 0Closing Time: Benjamin, Temporality, and (...) the Problem of Political Organization - Bennett Carpenter; 0Of Fish and Men: Benjamin's Allegorist and the Meaning of Life - Madeleine Kasten; 0Walter Benjamin on Charlie Chaplin: The Rehabilitation of the Allegorical in Modernity - Daniel Mourenza; 0THE NARRATOR AND THE POLITICS OF SENSES: 0"Drawing o an Unlikely Source": The "Erzähler", the Islamic Revival, and Benjamin's Philosophy of Language - Ton Groeneweg; 0TRANSLATION BETWEEN FOREIGNNESS AND KINSHIP: 0Bleakness in the Age of Google: Walter Benjamin and the Possibility of Redemptive Translation - Orr Scharf; 0Walter Benjamin's Translator/Critic as a Model for Transcultural Thought and Practice - Gisela Brinker-Gabler.; 0THE TASK OF CRITIC: 0Lektüre als Opfer: Der Kritiker in "Wider ein Meisterwerk" und dem Trauerspielbuch - Anna Wotkowicz; 0THE RIGHTEOUS AS MEDIATOR OF LINGUISTIC EXPERIENCE: 0"Im Anfang war das Wort": Von Adam, zwei Bäumen und dem Gerechten - Gerard Visser. (shrink)

In the nineteenth century protozoology and early cell biology intersected through the nexus of Darwin's theory of evolution. As single-celled organisms, amoebae offered an attractive focus of study for researchers seeking evolutionary relationships between the cells of humans and other animals, and their primitive appearance made them a favourite model for the ancient ancestor of all living things. Their resemblance to human and other metazoan cells made them popular objects of study among morphologists, physiologists, and even those investigating animal behaviour. (...) The amoeba became the exemplar of the new protoplasmic cell concept of mid-century and because its apparent simplicity made it widely generalizable it became a popular subject in a breadth of experimental investigations and theoretical speculations. It was able to do this because "the amoeba" denotes not a particular organism, but a general type of behaviour common to the cells of a range of protozoa, simple plants and higher animals. Its status as an exemplary cell also rested upon auxiliary philosophical assumptions about what constitutes a primitive characteristic and the thesis that evolution is a progressive development of order from chaos. (shrink)

Wilson et al. focus on one class of AGL tasks: the cognitively demanding task of detecting non‐adjacent dependencies (NADs) among items. They provide a typology of the different types of NADs in natural languages and in AGL tasks. A range of cues affect NAD learning, ranging from the variability and number of intervening elements to the presence of shared prosodic cues between the dependent items. These cues, important for humans to discover non‐adjacent dependencies, are also found to facilitate NAD learning (...) in several nonhuman animal species. (shrink)

The Office of Human Research Protections was not justified in issuing findings against the SUPPORT Institutions. Our community can learn from the evolving healthcare transformation into learning health systems by thinking about the novel ethical issues about standard of care research raised by the SUPPORT with the same spirit of quality improvement. The current regulatory framework and the concept of foreseeable research risks is insufficient to advance the debate about the ethics of randomization of standard clinical interventions. This article uses (...) the example of the Wisconsin cystic fibrosis randomized clinical trial for newborn screening trial to explore the distinctions between risks of research and clinical care and waivers of informed consent for randomization. Collaborative exploration of these complex policy issues is needed and further deliberation, community engagement, and social science research will be critical to advance novel approaches for informed consent. (shrink)

Volume 20, Issue 10, October 2020, Page 90-91.

The first philosophers of the Frankfurt School famously turned to the psychoanalytic theories of Sigmund Freud to supplement their Marxist analyses of ideological subjectification. Since the collapse of their proposed "marriage of Marx and Freud," psychology and social theory have grown apart to the impoverishment of both. Returning to this union, Benjamin Y. Fong reconstructs the psychoanalytic "foundation stone" of critical theory in an effort to once again think together the possibility of psychic and social transformation. Drawing on the (...) work of Hans Loewald and Jacques Lacan, Fong complicates the famous antagonism between Eros and the death drive in reference to a third term: the woefully undertheorized drive to mastery. Rejuvenating Freudian metapsychology through the lens of this pivotal concept, he then provides fresh perspective on Theodor Adorno, Max Horkheimer, and Herbert Marcuse's critiques of psychic life under the influence of modern cultural and technological change. The result is a novel vision of critical theory that rearticulates the nature of subjection in late capitalism and renews an old project of resistance. (shrink)

In April 2018, the International Association of Athletics Federations released new regulations placing a ceiling on women athletes’ natural testosterone levels to “ensure fair and meaningful competition.” The regulations revise previous ones with the same intent. They require women with higher natural levels of testosterone and androgen sensitivity who compete in a set of “restricted” events to lower their testosterone levels to below a designated threshold. If they do not lower their testosterone, women may compete in the male category, in (...) an intersex category, at the national level, or in unrestricted events. Women may also challenge the regulation, whether or not they have lowered their testosterone, or quit sport. Irrespective of IAAF’s stated aims, the options forced by the new regulations are impossible choices. They violate dignity, threaten privacy, and mete out both suspicion and judgement on the sex and gender identity of the athletes regulated. (shrink)

This new collection of philosophically rigorous essays critiques the interpretation of divine omniscience known as open theism, focusing primarily on philosophically motivated open theism and positing arguments that reject divine knowledge of future contingents in the face of the dilemma of freedom and foreknowledge. The sixteen new essays in this collection, written by some of the most renowned philosophers on the topic of divine providence, represent a philosophical attempt to seriously consider open theism. They cover a wide variety of issues, (...) including: the ontology of time, systematic metaphysics, perfect being theology, the Christian doctrine of the Incarnation, the problem of evil, and the nature of divine knowledge in general. _Philosophical Essays Against Open Theism _advances the discussion by wrestling against the assertions of open theism, and will be of interest to both proponents and opponents of this controversial issue. (shrink)

Background Executive functions (EFs) not only play an important role in shaping adolescent’s goal-directed, future-oriented cognitive skills under relatively abstract, non-affective conditions (Cool EF), but also under motivationally significant, affective conditions (Hot EF). Empirical evidence suggest a link between EF, exercise and physical activity, specifically elite adult athletes appear to outperform amateur athletes in Cool EF; however, no previous studies have examined the relationship between Hot and Cool EFs and impulsivity during the developmentally sensitive period of adolescence comparing different types (...) of sport (open- vs. closed-skills), and levels (elite athletes vs. amateurs). Methods A total 86 boys and girls between 13 and 15 years of age (mean: 14.0, SD : 0.79) from different sports (track-and-field; team handball) were recruited. Participants were further divided into two groups: (a) 40 elite, and (b) 46 amateur athletes. They completed four Cool EF tasks including Trail-Making Test, Trail-Walking-Test, Flanker task, n-back-task, and one Hot EF task on Game of Dice task. Data on subjective impulsivity (UPPS Impulsive Behavior Scale; Barratt Impulsiveness Scale-15) was also collected. Results There was a significant overall effect for expertise in favor of elite athletes (Wilks’ Lambda = 0.61, F (14,69) = 3.19, p = 0.001, η p 2 = 0.393), but no overall main effect for type of sport or an interaction for expertise by type of sport. Specifically, elite athletes showed significantly better performances on dual tasks. For Hot EF, there were no main effects for type of sport, expertise level, training experience or training duration. We also found positive correlations among Cool EF and impulsivity measures, and between Hot EF and Impulsivity, but no significant relationship between Cool and Hot EF. Conclusion The current understanding of the decisive cognitive abilities does not correspond to sporting reality, so that the tests frequently used are not sensitive enough to distinguish between elite and amateur athletes or different sports. However, it should also be remembered that the factors underlying complex sporting performance are multidimensional and are obviously difficult to trace back to selected partial aspects. Without being able to answer this question conclusively, we proposed a 4-D classification of experimental paradigms, in which we differentiate between tasks of different specificity, between Cool and Hot EF, and between task complexity, and type of sport. (shrink)

The paper begins by contrasting the unitary nature of conscious experience with the demonstrable localization of neural events. Philosophers and neuroscientists have developed models to account for this paradox, but they have yet to be tested empirically. The author proposes a `Conscious Mental Field', which is produced by, but is phenomenologically distinct from, brain activity. The hypothesis is, in principle, open to experimental verification. The paper suggests appropriate surgical procedures and some of the difficulties that would need to be overcome (...) in such an experiment. (shrink)

In this pilot study, deliberate practice and competence-based assessment were incorporated into a first-year graduate course on professional issues and ethics. Students responded to challenging simulations of basic ethical situations in therapy before and after the course. Aspects of deliberate practice were incorporated into the course. Student self-report ratings and independent performance ratings blind to timing found improvements in students’ ability to manage basic ethical situations in practice. Pilot evidence suggests competence-based assessment and training have potential use for training students (...) preparing to engage in their first therapy practicum experiences. Additional controlled studies are needed to examine the benefits of competence-based assessment and training. (shrink)

At least some of your beliefs are commitments. When you believe that P as a commitment, your stance on P is such that you believe it on the basis of your considered judgement. Sometimes, you also believe that you believe P. Such self‐beliefs can also be commissive in a sense, as when they are reflective endorsements of your lower‐order commissive beliefs. In this paper I argue that one's commissive self‐beliefs ontologically constitute one's lower‐order commissive beliefs because one's commissive self‐beliefs instantiate (...) the same inferential dispositions that are constitutive of one's lower‐order commissive beliefs. Constitutive relations between commissive self‐beliefs and first‐order commissive beliefs are maximally epistemically secure because they do not result from any epistemic procedure by which one must try (and possibly fail) to detect one's first‐order commissive beliefs. This maximal epistemic security suffices to warrant one's commissive self‐beliefs, such that one possesses commissive self‐knowledge of an especially privileged sort. (shrink)

Protein turnover (PT) has been formally defined only in equilibrium conditions, which is ill‐suited to quantify PT during dynamic processes that occur during embryogenesis or (extra) cellular signaling. In this Hypothesis, we propose a definition of PT in an out‐of‐equilibrium regime that allows the quantification of PT in virtually any biological context. We propose a simple mathematical and conceptual framework applicable to a broad range of available data, such as RNA sequencing coupled with pulsed‐SILAC datasets. We apply our framework to (...) a published dataset and show that stimulation of mouse dendritic cells with LPS leads to a proteome‐wide change in PT. This is the first quantification of PT out‐of‐equilibrium, paving the way for the analysis of biological systems in other contexts. (shrink)

Is a devoted Nazi or a zombie bureaucrat a greater moral and political problem? Because the dangers of immoral fanaticism are so clear, the dangers of mindless bureaucracy are easy to overlook. Yet zombie bureaucrats have contributed substantially to the greatest catastrophes of the 20th century, doing so seemingly oblivious to the monstrous qualities of their actions. Hannah Arendt’s work on thoughtlessness raises a dilemma: if Eichmann, the architect of the Nazi Final Solution, truly was a thoughtless ‘cog’, lacking in (...) intentionality, can one really hold him morally accountable for the evil qualities of his acts? This article relates Arendt’s ‘thought’ and Strawson’s and Bilgrami’s discussion of ‘reactive attitudes’ and Sartre’s concept of ‘bad faith’. To find a basis for moral accountable in seemingly thoughtless cases like Eichmann’s. Although Arendt’s Eichmann is an extreme example, finding a basis to hold him accountable is valuable because ‘little Eichmanns’ will persist as long as impersonal forces structure and depress reactive attitudes. (shrink)

We present a discrete model theory similar in structure to ordinary quantum mechanics, but based on a finite field instead of complex amplitudes. The interpretation of this theory involves only the “modal” concepts of possibility and necessity rather than quantitative probability measures. Despite its simplicity, our model theory includes entangled states and has versions of both Bell’s theorem and the no cloning theorem.

The authors put forward an interesting response to detractors of black box algorithms. According to the authors, what is of ethical relevance for medical artificial intelligence is not so much their transparency, but rather their reliability as a process capable of producing accurate and trustworthy results. The implications of this view are twofold. First, it is permissible to implement a black box algorithm in clinical settings, provided the algorithm’s epistemic authority is tempered by physician expertise and consideration of patient autonomy. (...) Second, physicians are not expected to possess exhaustive knowledge or understanding of the algorithmic computation by which they verify or augment their medical opinions. The potential of these algorithms to improve diagnostic and procedural accuracy alongside the quality of patient decision-making is undoubtedly a boon to modern medicine, but blind deference to them is neither feasible nor responsible, as several logistical and ethical quagmires noted by the authors still remain inherent in algorithmic software. I concur …. (shrink)

Sensation elicited by a skin stimulus was subjectively reported to feel stronger when followed by a stimulus to somatosensory cerebral cortex , even when C was delayed by up to 400 ms or more. This expands the potentiality for retroactive effects beyond that previously known as backward masking. It also demonstrates that the content of a sensory experience can be altered by another cerebral input introduced after the sensory signal arrives at the cortex. The long effective S-C intervals support the (...) thesis that a duration of cortical activity of up to 0.5 s is required before awareness of a sensory stimulus is developed. (shrink)

Throughout his theological career Stanley Hauerwas has struggled to maintain a demarcation between liberal and Christian ethics. Is such a separation theologically defensible? In an effort to deconstruct Hauerwas’s hostility to liberalism through Hauerwasian categories, the following article examines areas of resemblance between liberal and Hauerwasian ethics. Through a comparative reading of the liberalisms of J. S. Mill (1806–1873) and E. M. Forster (1879–1970), the following argument retrieves a neglected form of liberal politics which in many respects conforms to the (...) structure of Hauerwas’s radical description of Christian discipleship. Instead of understanding the Church as an isolated colony embattled against non-Christian culture, Mill and Forster challenge Hauerwas to consider the liberal polity as both the child and responsibility of the Church. (shrink)

What recourse do democrats have if a present generation uses democratic legal procedures to abrogate constitutional essentials, dissolving past commitments and denying future generations the fundamental freedoms and equalities it currently enjoys? In Sovereignty across Generations, Alessandro Ferrara responds to this issue by re-examining key concepts related to democracy, including sovereignty, constituent power, liberalism and constitutionalism. This review analyses Ferrara’s theory of ‘sequential sovereignty’, which reconceives ‘the people’ as a body spanning generations and grounds it in the ideal of vertical (...) reciprocity. Ferrara provides a sound normative framework for understanding transgenerational obligations and the unamendability of constitutional essentials. However, this review also identifies some limits to Ferrara’s approach: his focus on implied unamendability risks creating a dissonance between legality and legitimacy, and his reluctance to fully engage with ‘containment’ creates a blind spot in democracy’s self-defence. The review concludes that explicit unamendability and containment are consistent with Ferrara’s theory of sequential sovereignty and provide a better safeguard for democracy across generations. (shrink)

Many philosophers and legal theorists worry about punishing the socially disadvantaged as severely as their advantaged counterparts. One philosophically popular explanation of this concern is couched in terms of moral standing: seriously unjust states are said to lack standing to condemn disadvantaged offenders. If this is the case, institutional condemnation of disadvantaged offenders (especially via hard treatment) will often be unjust. I describe two problems with canonical versions of this view. First, its proponents groundlessly claim that disadvantaged offenders may be (...) punished as severely as advantaged ones, even though such punishment is unjust in light of the state’s loss of standing. Second, and more importantly, moral standing arguments prohibit states from blaming advantaged as well as disadvantaged offenders. This unwelcome outcome suggests that standing approaches incorrectly analyze the source of moral misgivings about punishing the disadvantaged. I conclude that those who share such concerns should put standing accounts aside. (shrink)

Hypocretin regulates brain reward function and cocaine consumption in rats. The hypocretinergic (Hcrt) system is implicated in energy homeostasis, feeding and sleep regulation. Hypocretinergic cell bodies are located in the lateral hypothalamus (LH) and project throughout the brain. The aim of the present studies was to investigate the role of the Hcrt system in regulating brain reward function and the reinforcing properties of cocaine in rats. Intracranial self-stimulation (ICSS) thresholds provide an accurate measure of brain reward function in rats. Here (...) we show that a single injection of Hcrt-1 (5 µg icv) induced persistent, long-lasting elevations in ICSS thresholds in drug-naïve rats. Indeed, Hrct-1 elevated ICSS thresholds for 36 h, with peak elevations between 6 and 12 hours after injection. Hrct-1-induced threshold elevations were attenuated by an antibody known to neutralize the binding of hcrt-1 to its receptors. Taken together, these observations suggest that Hrct-1 negatively regulates brain reward function in rats. Because Hrct-1 negatively regulates brain reward function, we hypothesized that it may attenuate the increased brain reward function usually observed after cocaine consumption, and thereby alter cocaine self-administration behavior. A daily injection of Hrct-1 (1 µg icv), for 4 consecutive days, slightly increased cocaine self-administration (0.25 mg/infusion) in rats. Overall, these data demonstrate that Hrct-1 negatively regulates brain reward function, and as such may indirectly alter cocaine self-administration. Given the well-established role of hypocretin neurons in regulating feeding behavior and sleep, we hypothesize that hypocretinergic regulation of brain reward function may provide a mechanism by which appropriate and competing behaviors (e.g. sleep or feeding) may be engaged to maintain energy homeostasis. (shrink)