BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

Este artigo tem como objetivo apresentar, como Introdução, a definição de Lógica como o estudo das formas válidas de raciocínio. Raciocinar é inferir conclusões de proposições tidas ou dadas por verdadeiros, denominadas premissas. Como estudo das formas válidas não é escopo da Lógica determinar se as premissas são verdadeiras ou falsa. Apenas considera as premissas como tidas por verdadeiras. A seguir trata-se da filosofia da ciência que estuda, entre outras questões, em que consiste a natureza da ciência, quais são suas (...) características, o que a diferencia do senso comum. Entre seus objetivos está em determinar em que consiste a explicação científica em especial o modelo da explicação dedutivo nomológico, sobretudo. Em terceiro lugar, trata-se deste modelo específico, que o tema central destas reflexões, sua estrutura um conjunto de proposições que constituem o Explanans no qual figuram 1. As condições iniciais em que se produz o fenômeno a ser explicado (denominado de Explanandum) e 2. As leis universais que estimadas como explicações do fenômeno a ser explicado. Do Explanans por meio de regras lógicas deduz-se o Explanandum. Este modelo é também denominado modelo de Hempel-Openheim considerado clássico e vigente até a década de 1960. A dedução lógica acarreta necessidade da ocorrência do Explanandum. A quarta secção do capítulo examina em que consiste esta necessidade, sobretudo quando é notório que em ciência tudo é revisível e sujeito ao princípio de incerteza de Heisenberg. Segue finalmente a conclusão. (shrink)

Big Water é um livro da estante dos Latin American Studies. Mais que isso, pretende definir os estudos sobre a tríplice fronteira entre Argentina, Brasil e Paraguai como um “novo campo de estudos históricos”. Trata-se de um livro coletivo, organizado por Jacob Blanc e Frederico Freitas, sobre “uma das áreas mais dinâmicas e menos estudada” da América Latina.

The paper examines a possible ethics for the current scenario, in order to bring human beings closer together and awaken in them a feeling of solidarity. For such an examination, at first, theories such as the utilitarianism reviewed by Rawls are questioned. It searches for a valid criterion for all participants of a certain universalism or for a real and non-exclusive “us”. The call for solidarity is proposed as a way of uniting people, as opposed to selfishness. Then solidarity is (...) defended, according to Richard Rorty. This philosopher affirms the need for an agreement among the members of society, because only then would there be a real “we”. Next, there is the question about how to make people more supportive, but without resorting to the traditional metaphysical perspective on humanity: there is a bet on the existence of shared characteristics that lead to democratic equality, however, respecting the differences of each one. It is still questioned what would lead the richest to sympathize with the poorest, observing the proposals made by Rorty about raising awareness, presenting the risk of poverty to the rich and appealing to the feeling of humanity. Finally, Rortyan egalitarianism is considered, according to which solidarity is beyond rationality. It would be historically constituted and based on the relationship with the other, on the common feeling of vulnerability, crucial to society in times of pandemic. (shrink)

This article examines the technique and legality of induced abortion of one or more fetuses in a multiple pregnancy, where the aim is the destruction of some but not all of the fetuses present (selective reduction of pregnancy). It concludes that since the legal status of the procedure in English law is unclear, it may be a criminal offence to perform selective reduction even where there is an ostensible clinical need. Moreover if the procedure is carried out negligently, and any (...) infant damaged as a result is subsequently born alive, he or she may have a civil claim against the practitioner who carried out the procedure. (shrink)

Russell’s distinction between knowledge by acquaintance and knowledge by description has been recently re-examined in frequently controversial epistemo-logical contributions. The present essay reflects upon the pertinent papers by D. F. Pears, J. Hintikka, R. Chisholm, W. Sellars, A. J. Ayer, and others, but is pri-marily founded on Russell’s significant formulations from his writings published between 1910 and 1918. By employing an auxiliary device of a late-Wittgen-steinian language game, I explore at first the situation in which human subject is “experiencing” and (...) naming particular objects and later the subject’s acquaintance with universals. The reconstruction of such situations shows that, contrary to Russell’s assumptions, even the “purest” acquaintance cannot function without knowledge by description, i.e. without sta-ting propositions about the object of acquaintance . Then the only “descriptionless” alternative would be a kind of intuitive knowledge of such objects which is difficult to reconcile with the position held by Russell in the 1910s. Whatever the consequences, this topic retains its fundamental epistemological significance. (shrink)

The paper proves that a historical method in Marxism is not identified to a dialectical method. The logic of history and the logic of its analysis in Marxism do not always coincide. The Logical coincides with the Historical only in eternity as it actually occurs in the works by G.V.F. Hegel. Eternity which has already witnessed everything does not know history any more. In the same way, history also begins there where the eternity comes to an end. Therefore, artificial identification (...) of the Logical with the Historical in Marxism led sometimes to actual mistakes. It is no wonder that it has always caused discussions in Marxism. They are mainly explained by the fact that the deductive, abstract-to-concrete method in which the “General” appears before the “Concrete” is an anti-historical method in its Nature. In real human history the “General” which is generalization of many “Concrete” could not appear before the latter in any way. For this reason, the real historical materialism needs an inductive method of knowledge. Only in that case historical materialism will cease to remain the soviet “histmat” and becomes the real form of a new world outlook. The author is of the opinion that the Party spirit of the Soviet philosophy promoted preservation of the anomalies mentioned in Marxism. The open discussion could help to find valid but not inherited from Hegel relation of historical and logical methods in Marxism. (shrink)

We investigate to what extent theorems about quantum mechanical or classical entropy can be generalized to functionals of the type ρ→Tr f(ρ), or ψ→∫f(ψ)dμ, respectively, wheref is an arbitrary concave function.

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The issue of sexual relations between spouses is a major cause of broken homes in Nigeria and Christian couples are not an exception. People believe that a large percentage of broken homes have the root of their problem traced to sex. The preponderance of broken homes notwithstanding, most studies in this area have been from the socio-scientific and medical cum psychological point of view and many more have focused on teenagers and young people to the exclusion of married couples that (...) need healing in this regard. This article is aimed at bringing out biblical instruction concerning the issue of sex that could help to restore peace to many homes at the verge of breaking down. The focal passage is 1 Corinthians 7:1–5, which was Paul’s instructions to the Corinthian church when they faced a similar problem. This article is an exegetical analysis of the passage and is read rhetorically with the Nigerian situation in mind. It concludes that sex must be enjoyed within the ambits of marriage and within this ambit, the only reason for abstinence is mutual agreement for the purpose of prayer.Contribution: The article upholds gender equality in initiating and enjoying sex and rejects looking down on women who request sex. It also calls for the eradication of female genital mutilation, a tradition based on making women not enjoy sex. (shrink)

Il testo analizza, in maniera ampia e analitica, un lavoro su Edourd Le Roy.

Seminar papers on the philosophical thoughts of the people of Bangladesh.