Abstract

This chapter considers individual differences associated with alcohol effects. There is wide variability in subjective and other responses to alcohol. The sources of this variability include allelic variation in enzymes responsible for the metabolism of alcoholism, sensitivity, temperament, neurocognitive functioning, and social learning. These sources of heterogeneity in alcohol response appear to be very important not only in understanding the acute effects of alcohol on the individual but also in understanding risk processes underlying the development of alcohol use disorders.