Abstract
The aim of this paper is to show, in the line suggested by Nickles (1980, 1981) and developed by Sintonen (1985, 1996), not just that the problem-solving approach and the theory approach are not incompatible, but also that the latter, in the version of the semantic conception of theories known as “structuralist view”, can be used to give precision to the problem-solving approach, by a more precise characterization of the theoretical context in which problems arise and, in this way, to their individuation and history, distinguishing two types of “problem change”: “change in a problem” and “change of a problem”. In order to do this, it will be presented a proposal that will be applied to the two first research programs in the field of genetics: the “mendelism” of Bateson and “classical genetics” of Morgan.