Abstract
Dmitri Mendeleev, while not creatively a philosopher of science, nor a student of systematic philosophy, was eminently a philosophical scientist. Concern about the nature and foundations of his science is evident throughout the text and footnotes of the Principles of Chemistry. One has to presume that his conclusions provided him with some direction for “the study of his great generalizations” in chemistry, especially for the greatest fruit of his efforts, the Periodic System of the Elements. At least it is apparent that somehow he acquired a much greater confidence in the feasibility of systemizing extant chemical knowledge than almost any of his contemporaries.