Abstract
Since its formal definition over sixty years ago, category theory has been increasingly recognized as having a foundational role in mathematics. It provides the conceptual lens to isolate and characterize the structures with importance and universality in mathematics. The notion of an adjunction (a pair of adjoint functors) has moved to center-stage as the principal lens. The central feature of an adjunction is what might be called "internalization through a universal" based on universal mapping properties. A recently developed "heteromorphic" theory of adjoint functors allows the concepts to be more easily applied empirically. This suggests a conceptual structure, albeit abstract, to model a range of selectionist mechanisms (e.g., in evolution and in the immune system). Closely related to adjoints is the notion of a "brain functor" which abstractly models structures of cognition and action (e.g., the generative grammar view of language).