Abstract

The making of mistakes by organisms and living systems generally is an underexplored way of conceptualising biology and organising experimental research. We set out an informal account of biological mistakes and why they should be taken seriously in biological investigation. We then give an indirect defence of their importance by applying the concept of mistake-making to three kinds of activity: timing, calculation, and communication. We give a range of examples to show that mistakes in these kinds of behaviour can be found across a diversity of scales and systems. We also suggest ideas for empirical research that naturally arise from these cases. The reality and potential for mistake-making across such a wide range of biological entities shows that it is not a purely human phenomenon. Getting it wrong seems to be central to biology as a whole, and to be a potentially productive organising principle for generating novel research questions and experimental hypotheses.