A study of how Derrida's acts of eulogy articulate the Levinasian ethical demand with a psychoanalytic account of ghosts.

Multisubunit protein complexes are essential for cellular function. Genetic analysis of essential processes requires special tools, among which temperature‐sensitive (Ts) mutants have historically been crucial. Many researchers assume that the effect of temperature on such mutants is to drive their proteolytic destruction. In fact, degradation‐mediated elimination of mutant proteins likely explains only a fraction of the phenotypes associated with Ts mutants. Here I discuss insights gained from analysis of Ts mutants in oligomeric proteins, with particular focus on the study of (...) septins, GTP‐binding subunits of cytoskeletal filaments whose structures and functions are the subject of current investigation in my and many other labs. I argue that the kinds of unbiased forward genetic approaches that generate Ts mutants provide information that is largely inaccessible to modern reverse genetic methodologies, and will continue to drive our understanding of higher‐order assembly by septins and other oligomeric proteins.Also watch the Video Abstract. (shrink)

Alan Turing, pioneer of computing and WWII codebreaker, is one of the most important and influential thinkers of the twentieth century. In this volume for the first time his key writings are made available to a broad, non-specialist readership. They make fascinating reading both in their own right and for their historic significance: contemporary computational theory, cognitive science, artificial intelligence, and artificial life all spring from this ground-breaking work, which is also rich in philosophical and logical insight.

"Money is plentiful for those who understand the simple laws which govern its acquisition." Read by millions, The Richest Man in Babylon is a classic that offers today's readers a path to success, prosperity, and happiness. Originally published in 1926 as a series of inspirational pamphlets for financial institutions, Clason's work offers financial advice for creating personal wealth using parables set in ancient Babylon. The stories, based on a fictional character, Arkad, are easy to read and packed with priceless wisdom. (...) Offering seven basic principles on saving and investing money, it's often cited as one of the most popular books ever written on the fundamentals of financial success. (shrink)

Swedish scientist-turned-seer Emanuel Swedenborg developed a deep theology that emphasized personal growth as the path to heaven and the presence of God in all of life. This book brings together key sections from Swedenborg's most popular writings in one place. What happens to us after we die? Why is there evil and suffering in the world? What is our purpose in life? Swedenborg answers all these questions and more.

States act wrongly. Sometimes, they are held responsible, or take responsibility of their own accord, to remediate their wrongdoing: they cease to act wron.

Outlines the ten ways to achieve happiness, discusses the relationship between health and happinesss, and examines the importance of cultivating human values.

Il s'agit de la première édition de cette oeuvre majeure de Bodin. Jusqu'ici seul le texte latin était disponible (éd. L. Noak, 1857), ou la traduction anglaise de 1975, par Mrs. Kuntz. Le texte donné ici est celui d'une traduction française anonyme écrite très tôt après la mort de l'auteur (1596), dans une langue proche de celle de la République. Bodin fait ici converser sept sages, un juif, un musulman, un catholique romain, un luthérien, un calviniste, un adepte de la (...) religion naturelle et un "ethnique" (indien d'Amérique) à propos des mérites de leurs religions respectives. Loin de donner l'avantage au christianisme, il semble montrer une certaine inclinaison au judaïsme qui fera les délices des libertins du XVIIe siècle... (shrink)

The Quest for Happiness Is a Universal Fact. It is a scientific fact, which means we can measure happiness, we can assess it, and we can devise strategies to make ourselves happy and fulfilled human beings. So says Professor Gad Saad, the author of the sensational bestseller The Parasitic Mind and the irrepressible host of The Saad Truth podcast. In this provocative, entertaining, and life-changing new book, he roams through the scientific studies, culls the wisdom of ancient philosophy and religion, (...) and draws on his extraordinary personal experience as a refugee from war-torn Lebanon turned academic celebrity. (shrink)

Alan M. Turing, pioneer of computing and WWII codebreaker, is one of the most important and influential thinkers of the twentieth century. In this volume for the first time his key writings are made available to a broad, non-specialist readership. They make fascinating reading both in their own right and for their historic significance: contemporary computational theory, cognitive science, artificial intelligence, and artificial life all spring from this ground-breaking work, which is also rich in philosophical and logical insight. An introduction (...) by leading Turing expert Jack Copeland provides the background and guides the reader through the selection. About Alan Turing Alan Turing FRS OBE, (1912-1954) studied mathematics at King's College, Cambridge. He was elected a Fellow of King's in March 1935, at the age of only 22. In the same year he invented the abstract computing machines - now known simply as Turing machines - on which all subsequent stored-program digital computers are modelled. During 1936-1938 Turing continued his studies, now at Princeton University. He completed a PhD in mathematical logic, analysing the notion of 'intuition' in mathematics and introducing the idea of oracular computation, now fundamental in mathematical recursion theory. An 'oracle' is an abstract device able to solve mathematical problems too difficult for the universal Turing machine. In the summer of 1938 Turing returned to his Fellowship at King's. When WWII started in 1939 he joined the wartime headquarters of the Government Code and Cypher School (GC&CS) at Bletchley Park, Buckinghamshire. Building on earlier work by Polish cryptanalysts, Turing contributed crucially to the design of electro-mechanical machines ('bombes') used to decipher Enigma, the code by means of which the German armed forces sought to protect their radio communications. Turing's work on the version of Enigma used by the German navy was vital to the battle for supremacy in the North Atlantic. He also contributed to the attack on the cyphers known as 'Fish'. Based on binary teleprinter code, Fish was used during the latter part of the war in preference to morse-based Enigma for the encryption of high-level signals, for example messages from Hitler and other members of the German High Command. It is estimated that the work of GC&CS shortened the war in Europe by at least two years. Turing received the Order of the British Empire for the part he played. In 1945, the war over, Turing was recruited to the National Physical Laboratory (NPL) in London, his brief to design and develop an electronic computer - a concrete form of the universal Turing machine. Turing's report setting out his design for the Automatic Computing Engine (ACE) was the first relatively complete specification of an electronic stored-program general-purpose digital computer. Delays beyond Turing's control resulted in NPL's losing the race to build the world's first working electronic stored-program digital computer - an honour that went to the Royal Society Computing Machine Laboratory at Manchester University, in June 1948. Discouraged by the delays at NPL, Turing took up the Deputy Directorship of the Royal Society Computing Machine Laboratory in that year. Turing was a founding father of modern cognitive science and a leading early exponent of the hypothesis that the human brain is in large part a digital computing machine, theorising that the cortex at birth is an 'unorganised machine' which through 'training' becomes organised 'into a universal machine or something like it'. He also pioneered Artificial Intelligence. Turing spent the rest of his short career at Manchester University, being appointed to a specially created Readership in the Theory of Computing in May 1953. He was elected a Fellow of the Royal Society of London in March 1951 (a high honour). (shrink)

Jacques Derrida argues that the feminist and intellectual Hélène Cixous is the most important writer working within the French idiom today. To prove this, he elucidates the epistemological and historical interconnectedness of four terms: genesis, genealogy, genre, and genius, and how they pertain to or are implicated in Cixous's work. Derrida explores Cixous's genius and the inspiration that guides and informs her writing. He marvels at her skillful working within multiple genres. He focuses on a number of her works, including (...) her extraordinary novel _Manhattan_ and her lyrical and evocative _Dream I Tell You_, a book addressed to Derrida himself and one in which Cixous presents a series of her dreams. Derrida also delves into the nature of the literary archive, the production of literature, and the importance of the poetic and sexual difference to the entirety of his own work. For forty years, Derrida had a close personal and intellectual relationship with Hélène Cixous. Clever, playful, and eloquent, _Geneses, Genealogies, Genres, and Genius_ charts the influence these two critical giants had on each other and is the most vital work to address Cixous's contribution to French thought. (shrink)

What follows is an attempt to do some conceptual housekeeping around the notion of secret law as provided by Christopher Kutz (2013). First I consider low-salience (or merely obscure) law, suggesting that it fails to capture the legal and moral facts that are at stake in the case which Kutz used to motivate it. Then I outline a theoretical contrast between mere obscurity and secrecy, in contrast to the 'neutral' account of secrecy provided by Sissela Bok (1989). The upshot of (...) the two sections is that low-salience law is neither secret law nor necessarily problematic, though it closely resembles a kind of law that is both secret and problematic: namely, those legal obscurities that subvert manifest interests related to the informational needs of citizens. The ensuing argument undermines the fiction of constructive presence found in Austin and Blackstone. (shrink)

Belonging to Hebrew Wisdom literature, the Song of Songs offers a fresh look at love and relationships through its main female character, the Shulamite, which profoundly differs from traditional, religious approaches to love and sexuality. Drawing from exegetical as well as philosophical resources, Abi Doukhan follows the Shulamite's journey away from patriarchy to her own self-individuation as she discovers a wisdom that is deeply personal and feminine.

The chorion genes of Drosophila are amplified in response to developmental signals in the follicle cells of the ovary prior to their transcription. Their expression is regulated both temporally and spatially within this tissue. They thus serve as models both for the regulation of DNA replication and of developmental transcription. The regulatory elements for DNA amplification have been delineated. Their analysis reveals that amplification is mediated by several regulatory regions and initiates at defined origins within the chorion cluster. Proteins involved (...) in amplification are being identified both by mutations affecting amplification and by DNA binding studies. Regulatory elements for temporal as well as spatial control of chorion gene, expression have been characterized, and two candidate transcription factor genes have been cloned. (shrink)