Though there has been an array of methods to evaluate the extent of sarcoidosis, it is generally difficult to detect central nervous system involvement. Recently it has become accepted that 18F-FDG PET is more sensitive than gallium scintigraphy in finding sarcoid lesions, however its usefulness and limitations for detecting sarcoidosis in the central nervous system, especially in the spinal cord, has rarely been investigated. Two patients with pathologically confirmed sarcoidosis manifested spinal symptoms. We conducted 18F-FDG PET along with conventional imagings (...) before and after treatment. Abnormal FDG uptakes which could not be detected by gallium scintigraphy were shown in the spinal cords in both patients. These abnormal uptakes were diminished in accordance with clinical improvement after treatment. Our findings suggest that 18F-FDG PET is effective in detecting and tracking the activity of spinal sarcoidosis. (shrink)

Modal realism -- Time, space, world -- Existence -- Actuality -- Modal realism and modal tense -- Transworld individuals and their identity -- Existensionalism -- Impossibility -- Proposition and relief -- Fictional worlds -- Epistemology.

How is that when scientists need some piece of mathematics through which to frame their theory, it is there to hand? What has been called 'the unreasonable effectiveness of mathematics' sets a challenge for philosophers. Some have responded to that challenge by arguing that mathematics is essentially anthropocentric in character, whereas others have pointed to the range of structures that mathematics offers. Otavio Bueno and Steven French offer a middle way, which focuses on the moves that have to be made (...) in both the mathematics and the relevant physics in order to bring the two into appropriate relation. This relation can be captured via the inferential conception of the applicability of mathematics, which is formulated in terms of immersion, inference, and interpretation. In particular, the roles of idealisations and of surplus structure in science and mathematics respectively are brought to the fore and captured via an approach to models and theories that emphasize the partiality of the available information: the partial structures approach. The discussion as a whole is grounded in a number of case studies drawn from the history of quantum physics, and extended to contest recent claims that the explanatory role of certain mathematical structures in scientific practice supports a realist attitude towards them. The overall conclusion is that the effectiveness of mathematics does not seem unreasonable at all once close attention is paid to how it is actually applied in practice. (shrink)

Introduction of the philosophy of Pavlos Kalligas.

Molecular and biochemical analysis of the biogenesis of peroxisomes has made rapid progress in recent years. Research on the mechanism of targeting of peroxisomal proteins has revealed that many, but not all, peroxisomal proteins have a conserved tripeptide motif in their carboxy‐terminal portions which is required for entry into peroxisomes; the topogenic signal mechanism thus differs in these instances from those employed in mitochondria and endoplasmic reticulum. Other factors involved in peroxisome biogenesis are also coming to light.

Ota Weinberger versucht, die logische Analyse für die theologische Argumentation nutzbar zu machen und Forderungen für eine Moral des friedfertigen Diskurses aufzustellen.Hierzu bestimmt er zunächst eine logische und methodologische Charakteristik des Glaubensoperators der Religionen. Nach einer Diskussion des Begriffes der möglichen Welten wird das Theodizeeproblem skeptisch beleuchtet. Zur Konstitution der Willensfreiheit ist weder die Existenz der ontologischen noch des moralischen Bösen erforderlich. Auch ist die Notwendigkeit des Bösen zum Nutzen der Geschöpfe nicht beweisbar. Es gehört jedoch zur Sichtweise der Theologen, (...) daß moralische Momente als Determinanten der Glückseligkeit angesehen werden.Der Autor stellt der Konzeption des Weltethos eine Theorie gegenüber, derzufolge das politische Geschehen durch das Aufeinanderprallen verschiedener Zivilisationen bestimmt ist. Weinberger setzt der gängigen Moral, die den Einsatz für die eigene Gemeinschaft fordert, eine Moral entgegen, die Wege der diskursiven Brücken zwischen divergierenden Welthaltungen sucht. Am Ende diskutiert er Methoden der friedlichen Koexistenz und Kooperation - trotz unterschiedlicher Einstellungen. (shrink)

Thirteen up-and-coming researchers in the philosophy of mathematics have been invited to write on what they take to be the right philosophical account of mathematics, examining along the way where they think the philosophy of mathematics is and ought to be going. A rich and diverse picture emerges. Some broader tendencies can nevertheless be detected: there is increasing attention to the practice, language and psychology of mathematics, a move to reassess the orthodoxy, as well as inspiration from philosophical logic.

dicates implying a surplus in the background from previous negation) and the other three combinations . The second part of the study in relation to the issue of intersubjectivity summarizes Hegel's unhappy consciousness analysis of figures from the Phenomenology of Spirit and shows that it takes insufficient account of Hegel older authors, which is just Dionysios. In writings on mystical theology can find is the formal structure of intersubjectivity, and Hegel's analysis so they can not be correct.

「意識のクオリア」も五感も、すべては錯覚だった。「心は脳が作り上げた幻想である」ことを述べた著者が、自己意識や五感が錯覚であることに的を絞って説明。.

Inspired by Rick Grush's emulation theory, we reinterpreted a series of our neuroimaging experiments which were intended to examine the representations of complex movement, modality-specific imagery, and supramodal imagery. The emulation theory can explain motor and cognitive activities observed in cortical motor areas, through the speculation that caudal areas relate to motor-specific imagery and rostral areas embrace an emulator for amodal imagery.

闇斎門下の個性豊かな諸家の事跡を通して、垂加神道の史的展開を検討すると共に、『日本書紀』神代巻の解釈に見える思想の根幹を明らかにする。.

In Kagaku no Sekai to Kokoro no Tetsugaku, Mr.Michio Kobayashi features on Descartes' theory of minds as "subjecitive-active consciousness", and defends it against the materialist movement. I show that Kobayashi's method has a difficulty for defending existence of our minds because Descartes didn't allow the scientific investigation of our mental experience from outside,and so cannot appropriately grasp the significance of other minds.

This book constitutes the thoroughly refereed joint post-proceedings of three international workshops organized by the Japanese Society for Artificial Intelligence, held in Tokyo, Japan in June 2006 during the 20th Annual Conference JSAI 2006. The volume starts with eight award winning papers of the JSAI 2006 main conference that are presented along with the 21 revised full workshop papers, carefully reviewed and selected for inclusion in the volume.

Sherlock Holmes is a fictional individual. So is his favorite pipe. Our pre-theoretical intuition says that neither of them is real. It says that neither of them really, or actually, exists. It also says that there is a sense in which they do exist, namely, a sense in which they exist “in the world of” the Sherlock Holmes stories. Our pre-theoretical intuition says in general of any fictional individual that it does not actually exist but exists “in the world of” (...) the relevant fiction. I wish to defend this pretheoretical intuition. To do so, I need to defend two claims: that fictional individuals do not actually exist, and that they exist “in the world of” the relevant fiction. The aim of this paper is to defend the first claim. (shrink)