Polynomial clone reducibilities are generalizations of the truth-table reducibilities. A polynomial clone is a set of functions over a finite set X that is closed under composition and contains all the constant and projection functions. For a fixed polynomial clone ${\fancyscript{C}}$ , a sequence ${B\in X^{\omega}}$ is ${\fancyscript{C}}$ -reducible to ${A \in {X}^{\omega}}$ if there is an algorithm that computes B from A using only effectively selected functions from ${\fancyscript{C}}$ . We show that if A is Kurtz (...) random and ${\fancyscript{C}_{1} \nsubseteq \fancyscript{C}_{2}}$ are polynomial clones, then there is a B that is ${\fancyscript{C}_{1}}$ -reducible to A but not ${\fancyscript{C}_{2}}$ -reducible to A. This implies a generalization of a result first proved by Lachlan (Z Math Logik Grundlagen Math 11:17–44, 1965) for the case |X| = 2. We also show that the same result holds if Kurtz random is replaced by Kolmogorov–Loveland stochastic. (shrink)

Cloning research caught a great deal of attention when Dolly the sheep was born (§4). While some fear surrounded the attainment (§§14-15), Wilmutʼs research itself has grown well, providing a less vicious manner to gain ES cells (§12). In this article, we review the progress of cloning research along with the concern of medical circles about its application to reproductive cloning, that is to say, making replicas of human beings (§§16-21). Note that all the content is ascribed to the author (...) alone, not to Musashino University. (shrink)

ABSTRACT Many people now believe that human reproductive cloning – once sufficiently safe and effective – should be permitted on the grounds that it will allow the otherwise infertile to have children that are biologically closely related to them. However, though it is widely believed that the possession of a close genetic link to our children is morally significant and valuable, we argue that such a view is erroneous. Moreover, the claim that the genetic link is valuable is pernicious; it (...) tends to give rise to highly undesirable consequences, and therefore should be combated rather than pandered to. The emphasis on the genetic is unwarranted and unfortunate; rather than giving us moral reason to support reproductive cloning in the case of infertility, the fact that cloning requests are likely to be motivated by the genetic argument gives us reason to oppose its availability. (shrink)

We have two polynomial time results for the uniform word problem for a quasivariety Q: The uniform word problem for Q can be solved in polynomial time iff one can find a certain congruence on finite partial algebras in polynomial time. Let Q* be the relational class determined by Q. If any universal Horn class between the universal closure S and the weak embedding closure S̄ of Q* is finitely axiomatizable then the uniform word problem for Q (...) is solvable in polynomial time. This covers Skolem's 1920 solution to the uniform word problem for lattices and Evans' 1953 applications of the weak embeddability property for finite partial V algebras. (shrink)

It is shown in this article that the two sides of an equation in the medieval Arabic algebra are aggregations of the algebraic “numbers” (powers) with no operations present. Unlike an expression such as our 3x + 4, the Arabic polynomial “three things and four dirhams” is merely a collection of seven objects of two different types. Ideally, the two sides of an equation were polynomials so the Arabic algebraists preferred to work out all operations of the enunciation to (...) a problem before stating an equation. Some difficult problems which involve square roots and divisions cannot be handled nicely by this basic method, so we do find square roots of polynomials and expressions of the form “A divided by B” in some equations. But rather than initiate a reconsideration of the notion of equation, these developments were used only for particularly complex problems. Also, the algebraic notation practiced in the Maghreb in the later middle ages was developed with the “aggregations” interpretation in mind, so it had no noticeable impact on the concept of polynomial. Arabic algebraists continued to solve problems by working operations before setting up an equation to the end of the medieval period. (shrink)

We study the notion of polynomial-time relation reducibility among computable equivalence relations. We identify some benchmark equivalence relations and show that the reducibility hierarchy has a rich structure. Specifically, we embed the partial order of all polynomial-time computable sets into the polynomial-time relation reducibility hierarchy between two benchmark equivalence relations Eλ and id. In addition, we consider equivalence relations with finitely many nontrivial equivalence classes and those whose equivalence classes are all finite.

Hailed as revolutionary, the prospect of human cloning is actually the next logical step in a series of developments in reproductive technology that began with the first test-tube baby in 1978. This book addresses the debates over cloning in the context of new reproductive technology and human embryo research. It examines the status of preimplantation embryos, the ethical issues related to cloning and embryo research, and the formulation of public policy.

Cloning - few words have as much potential to grip our imagination or grab the headlines. No longer the stuff of science fiction or Star Wars - it is happening now. Yet human cloning is currently banned throughout the world, and therapeutic cloning banned in many countries. In this highly controversial book, John Harris does a lot more than ask why we are so afraid of cloning. He presents a deft and informed defence of human cloning, carefully exposing the rhetorical (...) and highly dubious arguments against it. He begins with an introduction to what a human clone is, before tackling some of the most common and frequently bizarre criticisms of cloning: Is it really wicked? Can we regulate it? What about the welfare of cloned children? Does it turn human beings into commodities? Dismissing one by one some of the myths about human cloning, in particular that it is degrading and unsafe, he astutely argues that some of our most cherished values, such as the freedom to start a family and the freedom from state control, actually support the case for human cloning. Offering a brave and lucid insight into this ethical minefield, John Harris at last shows that far from ending the diversity of human life or creating a race of super-clones, cloning has the power to improve and heal human life. (shrink)

This paper is motivated by the question whether there exists a logic capturing polynomial time computation over unordered structures. We consider several algorithmic problems near the border of the known, logically defined complexity classes contained in polynomial time. We show that fixpoint logic plus counting is stronger than might be expected, in that it can express the existence of a complete matching in a bipartite graph. We revisit the known examples that separate polynomial time from fixpoint plus (...) counting. We show that the examples in a paper of Cai, Fürer, and Immerman, when suitably padded, are in choiceless polynomial time yet not in fixpoint plus counting. Without padding, they remain in polynomial time but appear not to be in choiceless polynomial time plus counting. Similar results hold for the multipede examples of Gurevich and Shelah, except that their final version of multipedes is, in a sense, already suitably padded. Finally, we describe another possible candidate, involving determinants, for the task of separating polynomial time from choiceless polynomial time plus counting. (shrink)

It seemed like only minutes after a team of Scottish scientists announced, in late February 1997, that they had successfully cloned a sheep, that governmental officials and private citizens throughout the world called for a ban on cloning human beings. The rush to legislate or issue executive orders was so swift, it is reasonable to wonder why the news that a mammal had been cloned ignited such a stampede to prohibit, even criminalize, attempts to clone humans. These events raise a (...) series of separate, yet related questions. Why does the prospect of cloning human beings incite such strong reactions? What reasons have been proposed for enacting national laws or international conventions to prohibit cloning? Can these prohibitions be justified by sound ethical arguments? Before attempting to answer these questions, let us look first at the responses that called for public policy measures to ban human cloning. (shrink)

Sierpinski networks are networks of fractal nature having several applications in computer science, music, chemistry, and mathematics. These networks are commonly used in chaos, fractals, recursive sequences, and complex systems. In this article, we compute various connectivity polynomials such as M -polynomial, Zagreb polynomials, and forgotten polynomial of generalized Sierpinski networks S k n and recover some well-known degree-based topological indices from these. We also compute the most general Zagreb index known as α, β -Zagreb index and several (...) other general indices of similar nature for this network. Our results are the natural generalizations of already available results for particular classes of such type of networks. (shrink)

A polynomial time ultrapower is a structure given by the set of polynomial time computable functions modulo some ultrafilter. They model the universal theory \ of all polynomial time functions. Generalizing a theorem of Hirschfeld :111–126, 1975), we show that every countable model of \ is isomorphic to an existentially closed substructure of a polynomial time ultrapower. Moreover, one can take a substructure of a special form, namely a limit polynomial time ultrapower in the classical (...) sense of Keisler Ultrafilters across mathematics, contemporary mathematics vol 530, pp 163–179. AMS, New York, 1963). Using a polynomial time ultrapower over a nonstandard Herbrand saturated model of \ we show that \ is consistent with a formal statement of a polynomial size circuit lower bound for a polynomial time computable function. This improves upon a recent result of Krajíček and Oliveira, 2017). (shrink)

The announcement of the birth of Dolly the cloned sheep evoked widespread response from the Christian Churches. These responses are identified, organized thematically, and discussed critically. The churches have viewed reproductive human cloning either with unqualified opposition or with grave suspicion. Some statements have discussed animal cloning, generally granting limited approval, and nonreproductive human cloning, either in opposition or expressing an openness to entertain specific proposals as the technology develops.

The creation of a cloned sheep from mammary tissue has raisedmajor social concern, and much talk about major ethical issuesoccasioned by this technology. It is necessary to separategenuine from spurious ethical issues here, a task made failureto initiate ethical discussion and explanation of new technologyas well as by fear reactions in society. As in geneticengineering of animals, issues about cloning fall into threecategories – suggestions that the technology is inherently wrong,risk emerging from the technology and harm to the creatureengendered. The (...) issues regarding the cloning of humans can beanalyzed using the same categories. (shrink)

In Human Cloning a panel of distinguished philosophers, medical ethicists, religious thinkers, and social critics tackle the thorny problems raised by the now real possibility of human cloning. In their wide ranging reviews, the distinguished contributors critically examine the major arguments for and against human cloning, probe the implications of such a procedure for society, and critically evaluate the "Report and Recommendations of the National Bioethics Advisory Commission." The debate includes both religious and secular arguments, as well as an outline (...) of the history of the cloning debate and a discussion of human cloning's impact on our sense of self and our beliefs about the meaning of life. (shrink)

Cancers are hard to treat, and this is largely because cancer cells evolve and diversify through space and time, in patients. The study of clonal evolution relies on the study of cancer cell lineages, and the cutting of these lineages into clones, each clone representing cancer cells with distinctive properties relevant to cancer development and treatment. This notion of clone implies a (set of) simplification(s) that misrepresents the reality. The simplification has been useful and productive, but I argue that (...) maintaining a critical awareness of what is done through this simplification can also be useful and productive. I distinguish three types of simplifications and show that each can offer a panel of therapeutic alternatives that may complement our arsenal of strategies in the battle against clones. The clinical challenge of better treating cancer partly relies on better defining (delineating) clones, but also partly on the more fundamental way we conceive clones. With or without changing the definition, changes in the way we conceive of clones induce changes in the way we treat clones. (shrink)

A common feature of scientific and ethical debates is that clones are generally described and understood as “copies” or, more specifically defined, as “genetic copies.” The attempt of this paper is to question this widespread definition. It first argues that the terminology of “clone as copy” can only be understood as a metaphor, and therefore, a clone is not a “genetic copy” in a strict literal sense, but in a figurative one. Second, the copy metaphor has a normative component (...) that is problematic in the context of descriptive science and may support or indicate the ethically relevant phenomenon of objectification of animals. In order to support the argument against the common conception of a clone as a copy, the biotechnological principles of somatic cell nuclear transfer cloning will be examined. On this basis, it will be shown that the metaphor is valid because of similarities between the phenotype, the genotype, or the nuclear DNA sequence of the clone and its progenitor by using three prominent levels of comparison. Focusing on the process of SCNT, it will be shown that cloning as copying or doubling has to be redefined for scientific purposes because it is neither necessary nor does it fit to the biotechnological principles of cloning. It is more accurate to understand SCNT cloning as a process of splitting rather than of doubling or copying. In the second part, a deconstructivist analysis based on Jacques Derrida’s description in Positions will reveal the normative potential of the original–copy dichotomy. I will be showing that it includes an asymmetrical power structure between the original and the copy and that this structure can be reversed or at least considered unstable. Therefore, arguments that build on that metaphor must be reconsidered. Moreover, the analysis reveals that applying a terminology to humans and animals that is commonly used for things becomes the language of objectification. Two selected examples, fungibility and violability, based on Martha Nussbaum’s notion of objectification will support the thesis of objectification, display its normative consequences, and put the clone as a copy metaphor in a broader range of ethically questionable research tendencies. (shrink)

As the #1 topic in bioethics, cloning has made big news since Dolly's announced birth in 1998. In a new book building on his classic Who's Afraid of Human Cloning?, pioneering bioethicist Gregory E. Pence continues to advocate a reasoned view of cloning. Beginning with his surreal experiences as an expert witness before Congressional and California legislative committees, Pence analyzes the astounding recent progress in animal cloning; the coming surprises about human cloning; the links between animal, stem cell, and human (...) cloning; embryo politics; and other hot topics like artificial wombs and transgenic animals. -/- Pence rebuts the growing chorus of naysayers headed by Leon Kass, chairman of the President's Council on Bioethics, who attack the biomedical sciences, and explains why cloning will save endangered species and beloved pets, and help future children and people with degenerative diseases. (shrink)

Human cloning until recently has been considered to belong to the domain of science fiction; now it is a tangible possibility, a hopeful as well as a fearsome one. One of the fears that necessarily come along with it is about the peril cloning might represent for human uniqueness, since the clones are expected to be identical to their prototypes; this would unavoidably compromise moral agents’ right to a unique identity. In this paper I will put under examination the (...) argument against cloning that is based upon the right to a unique identity; I will argue that cloning represents no actual threat for anybody’s unique identity, therefore this argument is futile. I will also support the view that the so-called right to a unique identity is not as indisputable as to serve as the basis of a moral argument against human reproductive cloning. (shrink)

Cook and Reckhow defined a propositional formulation of the pigeonhole principle. This paper shows that there are Frege proofs of this propositional pigeonhole principle of polynomial size. This together with a result of Haken gives another proof of Urquhart's theorem that Frege systems have an exponential speedup over resolution. We also discuss connections to provability in theories of bounded arithmetic.

We show, under the assumption that factoring is hard, that a model of PV exists in which the polynomial hierarchy does not collapse to the linear hierarchy; that a model of S21 exists in which NP is not in the second level of the linear hierarchy; and that a model of S21 exists in which the polynomial hierarchy collapses to the linear hierarchy. Our methods are model-theoretic. We use the assumption about factoring to get a model in which (...) the weak pigeonhole principle fails in a certain way, and then work with this failure to obtain our results. As a corollary of one of the proofs, we also show that in S21 the failure of WPHP (for Σb1 definable relations) implies that the strict version of PH does not collapse to a finite level. (shrink)

In this paper I examine what I take to be the best case for reproductive human cloning, as a medical procedure designed to overcome infertility, and argue that it founders on an irresolvable tension in the attitude towards the importance of being ‘genetically related’ to our children implied in the desire to clone. Except in the case where couples are cloning a child they have previously conceived naturally, cloning is unable to establish the right sort of genetic relation to make (...) couples the parents of their cloned child. If anybody is the genetic parent of a cloned child it is the natural parent(s) of the DNA donor. Paradoxically, in order to resist the claims of the parents of the donor to the cloned child, the argument for human reproductive cloning must place more weight on the intention to parent a child, than we do in cases of ordinary reproduction. It must insist that the parental relation is established by the intentions of the couple who bring a clone into the world and not by their genetic relation to the child. The emphasis placed on intention as establishing the parental relationship works to undermine the justification for cloning in the first place. For cloning to play a useful role as a reproductive technology, it must allow couples to become parents who could do so no other way. However, to the extent that intention is sufficient to establish parenthood, adoption or surrogacy, which are existing alternatives to cloning, will serve equally well to allow couples to become parents. (shrink)

The purpose of this paper is to show that arguments for and against cloning fail to make their case because of one or both of the following reasons: 1) they take for granted customary beliefs and assumptions that are far from being unquestionable; 2) they tend to ignore the context in which human cloning is developed. I will analyze some of the assumptions underlying the main arguments that have been offered for and against cloning. Once these assumptions are critically analyzed, (...) arguments both rejecting and supporting human cloning seem to lose weight. I will first briefly present the main arguments that have been proposed against cloning and I will argue that they fail to establish their case. In the next section I will evaluate some of the positive arguments that have been offered supporting such technology. This analysis will show that the case for cloning also fails. Finally, I will maintain that because critics and especially supporters of this technology neglect the context in which human cloning is developed and might be implemented, their arguments are far from compelling. (shrink)

The central problem considered in this paper is whether a given recursive structure is recursively isomorphic to a polynomial-time structure. Positive results are obtained for all relational structures, for all Boolean algebras and for the natural numbers with addition, multiplication and the unary function 2x. Counterexamples are constructed for recursive structures with one unary function and for Abelian groups and also for relational structures when the universe of the structure is fixed. Results are also given which distinguish primitive recursive (...) structures, exponential-time structures and structures with honest witnesses. (shrink)

Since early 1997, when the creation of Dolly the sheep by somatic cell nuclear transfer was announced in Nature, numerous government reports, essays, articles and books have considered the ethical problems and policy issues surrounding human reproductive cloning. In this article, I consider what response a modern liberal society should give to the prospect of human cloning, if it became safe and practical. Some opponents of human cloning have argued that permitting it would place us on a slippery slope to (...) a repugnant future society, comparable to that portrayed in Aldous Huxley’s novel, Brave New World.I conclude that, leaving aside concerns about safety, none of the psychological or social considerations discussed in this article provides an adequate policy justification for invoking the state’s coercive powers to prevent human cloning. (shrink)

The author makes a review of the different meaning of the word “clone”. He refers on the new perspectives in fertilizing human eggs with somatic nucleus in order to obtain a zygote after having removed the original nucleus. The author moreover discusses the ethical implications.

ABSTRACT In previous articles I discussed the ethics of human reproductive cloning, focusing on a possible future scenario in which reproductive cloning can be accomplished without an elevated risk of anomalies to the children who are created. I argued that in such a scenario it would be ethically permissible for infertile couples to use cloning as a way to have genetically related children and that such use should not be prohibited. In ‘Reproductive Cloning and a (Kind of) Genetic Fallacy’, Neil (...) Levy and Mianna Lotz raise objections to my conclusions. They disagree with the view, for which I argued, that some couples can have defensible reasons for desiring genetically related children. They also offer several new arguments against reproductive cloning, including an argument that it would diminish the number of adoptions, thereby adversely affecting the welfare of children who need to be adopted. In this paper I point out that Levy and Lotz's criticisms misconstrue my arguments and that there are serious problems with their arguments for prohibiting infertile couples from using cloning, including their argument from adoption. (shrink)

No-cloning theorem says that there is no unitary operation that makes perfect clones of non-orthogonal quantum states. The objective of the present paper is to examine whether an imperfect cloning operation exists or not in a C*-algebraic framework. We define a universal \ -imperfect cloning operation which tolerates a finite loss \ of fidelity in the cloned state, and show that an individual system’s algebra of observables is abelian if and only if there is a universal \ -imperfect cloning (...) operation in the case where the loss of fidelity is less than \ . Therefore in this case no universal \ -imperfect cloning operation is possible in algebraic quantum theory. (shrink)

As the possibility of cloning humans emerges on the horizon people are worrying about the morality of using the new technology. They are anxious about the ethical borders that might be crossed when duplicate humans can be produced by separating the cells of a newly fertilized human egg or, in the more distant future, by creating a zygote from an existing person's genetic material. They are apprehensive about eugenics, concerned about creating humans as sources of spare parts for others, uneasy (...) about producing humans without intending to allow them to live and develop, and uncomfortable about using duplicate humans as business ventures. (shrink)

Cloning Trevor, a story about therapeutic cloning research, appeared in the June issue of The Atlantic Monthly. The story gives a human face to the people whom therapeutic cloning could benefit. It presents an argument for government funding and it puts the usual calls for a moratorium on embryonic stem cell research to allow for more debate, in a less favourable light. The story also highlights some problems with ethical oversight.

Although there are important moral arguments against cloning human beings, it has been suggested that there might be exceptional cases in which cloning humans would be ethically permissible. One type of supposed exceptional case involves infertile couples who want to have children by cloning. This paper explores whether cloning would be ethically permissible in infertility cases and the separate question of whether we should have a policy allowing cloning in such cases. One caveat should be stated at the beginning, however. (...) After the cloning of a sheep in Scotland, scientists pointed out that using the same technique to clone humans would, at present, involve substantial risks of producing children with birth defects. This concern over safety gives compelling support to the view that it would be wrong to attempt human cloning now. Thus, we do not reach the debate about exceptional cases unless the issue of safety can be set aside. I ask the reader to consider the possibility that in the future humans could be cloned without a significantly elevated risk of birth defects from the cloning process itself. The remainder of this paper assumes, for sake of argument, that cloning technology has advanced to that point. Given this assumption, would cloning in the infertility cases be ethically permissible, and should it be legally permitted? (shrink)

We give a counterexample to the claim that every provably total function of Basic Arithmetic is a polynomially bounded primitive recursive function.

The degree structure of functions induced by a polynomial-time reducibility first introduced in G. Miller's work on the complexity of prime factorization is investigated. Several basic results are established including the facts that the degrees restricted to the sets do not form an upper semilattice and there is a minimal degree, as well as density for the low degrees, a weak form of the exact pair theorem, the existence of minimal pairs and the decidability of the Π2 theory of (...) the low degrees. (shrink)

Some authors have argued that the human use of reproductive cloning and genetic engineering should be prohibited because these biotechnologies would undermine the autonomy of the resulting child. In this paper, two versions of this view are discussed. According to the first version, the autonomy of cloned and genetically engineered people would be undermined because knowledge of the method by which these people have been conceived would make them unable to assume full responsibility for their actions. According to the second (...) version, these biotechnologies would undermine autonomy by violating these people’s right to an open future. There is no evidence to show that people conceived through cloning and genetic engineering would inevitably or even in general be unable to assume responsibility for their actions; there is also no evidence for the claim that cloning and genetic engineering would inevitably or even in general rob the child of the possibility to choose from a sufficiently large array of life plans. (shrink)

A new proof style adequate for modal logics is defined from the polynomial ring calculus. The new semantics not only expresses truth conditions of modal formulas by means of polynomials, but also permits to perform deductions through polynomial handling. This paper also investigates relationships among the PRC here defined, the algebraic semantics for modal logics, equational logics, the Dijkstra???Scholten equational-proof style, and rewriting systems. The method proposed is throughly exemplified for S 5, and can be easily extended to (...) other modal logics. (shrink)

Cloning -- the process of creating a cell, tissue line or even a complete organism from a single cell -- or the strands that led to the cloning of a mammal, Dolly, are not new. Yet the media coverage of Dolly's inception raised a range of reactions from fear or moral repulsion, to cautious optimism. The implications for controlling human reproduction were clearly in the forefront, though many issues about animals emerged as well. On topics of public interest such as (...) cloning, historians of biology have the opportunity to make a unique contribution. Such debates are often aired as if they have no precedents, either in biology or in the ethical, moral, and social concerns arising in the public arena. The technology leading to Dolly draws on strands of research going back to the 1890s, and the cycle of public response has been repeated often in the past century. What can we learn from examining these events historically, and how can we -- or should we even try -- to inform public opinion? I think we should try and will outline briefly some of the ways that can work. (shrink)

This chapter contains sections titled: Process The Reaction to Cloning Arguments against Human Reproductive Cloning Procreative Autonomy Acknowledgments.

This chapter contains sections titled: Cloning and Popular Culture: A Brief History Some Facts About Cloning Exact Copies and Zombies Is Cloning Humans Unnatural? Animal Cloning Originating the First Cloned Baby Preliminary Psychological‐Social Objections to Cloning Moral Objections Against Human Embryonic Cloning Conclusions References.

This study has a twofold objective: firstly, it aims to examine the main types of argument that have been formulated against human cloning, to identify their presuppositions and to evaluate their strength; secondly, it aims to argue that the most important objections against human cloning are philosophical and religious, in particular the objection that human cloning represents a radical form of disenchantment or an abuse of rationality. The birth of a cloned mammal, a sheep named Dolly, which was announced on (...) 23 February 23 1997, began a wide public debate on the morality of human cloning. I shall try to show that this debate should not be limited only to ethical and legal considerations, since it has more profound ramifications. The science of cloning is rooted in a certain metaphysical background, which, discreetly, but firmly, accompanies its spectacular promises, and which has profound consequences on our metaphysical and religious beliefs. This background needs to be openly discussed and evaluated. Moreover, it warrants the special attention of philosophers and religious thinkers alike. . (shrink)

In this paper we study (self)-applicative theories of operations and binary words in the context of polynomial time computability. We propose a first order theory PTO which allows full self-application and whose provably total functions on W = {0, 1} * are exactly the polynomial time computable functions. Our treatment of PTO is proof-theoretic and very much in the spirit of reductive proof theory.

Someday soon (if it hasn't happened in secret already), a human will be cloned, and mankind will embark on a scientific and moral journey whose destination cannot be foretold. In Copycats: The Science and Ethics of Cloning, Arlene Judith Klotzko describes the new world of possibilities that can be glimpsed over the horizon. In a lucid and engaging narrative, she explains that the technology to create clones of living beings already exists, inaugurated in 1996 by Dolly the sheep, the (...) first mammal cloned from a single adult cell. Dolly is the culmination of a long scientific quest to understand the puzzle of our development from one cell into a complex organism--the outcome of a "fantastic experiment" envisioned six decades before her birth. Scientists have since cloned mice, cows, goats, pigs, rabbits and cats. Using the same laboratory tools and techniques, they are trying to grow an embryo, cloned from a single cell of a human being. Their goal is not to make copies of existing people, but to design therapies for currently untreatable diseases and the afflictions of old age. Our fascination with cloning is about much more than science and its extraordinary medical implications. In riveting prose, full of illusions to art, music and the cinema, Klotzko shows why the prospect of human cloning triggers our dearest hopes and especially our darkest fears, forcing us to ponder anew what it means to be human. And what it would be like to have "a clone of your own.". (shrink)

The prelims comprise: Introduction Public Policy Actions Strong Reactions to Human Cloning A Rational Approach to Public Policy.

The possibility of human reproductive cloning has led some bioethicists to suggest that potentiality-based arguments for fetal moral status become untenable, as such arguments would be committed to making the implausible claim that any adult somatic cell is itself a potential person. In this article I defend potentiality-based arguments for fetal moral status against such a reductio. Starling from the widely-held claim that the maintenance of numerical identity throughout successive changes places constraints on what a given entity can plausibly be (...) said to have the potential to become, I argue that the cell reprogramming that takes place in reproductive cloning is such that it produces a new individual, and so adult somatic cells cannot be potential persons. (shrink)

Creating a man by means of cloning will certainly raise many legal and halakhic questions. But is this sufficient reason to restrain human creativity? Artificial insemination as well as surrogate motherhood also brought many questions, among them questions concerning who is considered the child's father and who is considered the child's mother. But grave questions such as these arise in every field of human endeavor. The emergence of new questions is however not in itself reason to prohibit the creative endeavors (...) that give rise to them. (shrink)

This article explores literary interrogations of the bioethical implications of cloning. It does so by outlining the basic science of cloning before going on to question the dominance of the Freudian notion of the ‘uncanny’ in the critical theoretical responses to cloning by figures such as Jean Baudrillard and Slavoj Žižek. The second half of the article turns to two recent novels exploring the theme of cloning: Eva Hoffman's The Secret, and Kazuo Ishiguro's Never Let Me Go. It is argued (...) that the former rehearses familiar themes of revulsion connected to the figure of the clone, yet resolves the struggle for identity in a ‘human’ conclusion; whereas the latter maintains the uncanny in-human difference of the clone even as it highlights the dangers of the biopolitical instrumentalization of life itself. The article therefore argues that fictional treatments of cloning can provide an important alternative to simplified debates on the subject in the mass media. (shrink)

It is known that a countable $\omega $ -categorical structure interprets all finite structures primitively positively if and only if its polymorphism clone maps to the clone of projections on a two-element set via a continuous clone homomorphism. We investigate the relationship between the existence of a clone homomorphism to the projection clone, and the existence of such a homomorphism which is continuous and thus meets the above criterion.