It is argued that the social significance of nanotechnologies should be understood in terms of the politics and ethics of uncertainty. This means that the uncertainties surrounding the present and future development of nanotechnologies should not be interpreted, first and foremost, in terms of concepts of risk. It is argued that risk, as a way of managing uncertain futures, has a particular historical genealogy, and as such implies a specific politics and ethics. It is proposed, instead, that the (...) concepts of contingency and of finitude must be central to any understanding of the ethical significance of nanotechnologies, as these concepts can be used to understand the basis of recent work in science and technology studies, and the sociology of knowledge more widely, which details the multi-dimensional social nature of technological uncertainty. (shrink)

This article examines nanotechnology within the context of the public interest. It notes that though nanotechnology research and development investment totalled US$9.6 billion in 2005, the public presently understands neither the implications nor how it might be best governed. The article maps a range of nanotechnology dialogue activities under way within the United Kingdom, the United States, Germany, and Australia. It explores the various approaches to articulating public interest matters and notes a shift in the way in which these governments, (...) on the whole, appear to be attempting to manage nanotechnology “risks.” It argues that open and transparent policy deliberations and extensive public discourse will be pivotal to protecting the public interest, gaining public trust and acceptance of nanotechnologies. The article concludes that though governing emerging technologies in the public interest is not a new concept, nanotechnology does present additional challenges that must be addressed by the guardians of the public interest. (shrink)

The promise of scientific and technological innovation – particularly in fields such as nanotechnology – is increasingly set against what has been articulated as a deficit in public trust in both the new technologies and regulatory mechanisms. Whilst the development of new technology is cast as providing contributions to both quality of life and national competitiveness, what has been termed a ‘legitimacy crisis’ is seen as threatening the vitality of this process. However in contrast to the risk debates that dominated (...) the technological controversies of the late 1990s the vitality of technological innovation is now cast as vulnerable to lack of public confidence and trust in the regulatory and governance structures upon which such innovation depends. In order to address this deficit in public trust, science policy has increasingly turned to the social sciences, suggesting that public values might be incorporated into the development of nanotechnology at an early stage. Public ambivalence therefore constitutes the problem addressed by the increasingly central role that public engagement and participation play in contemporary science policy. Although the recent proliferation of public engagement activities is premised on the need to address this ambivalence through direct engagement, we re-interpret ambivalence as an engaged – rather than passive – mode of relating to technological determinism. Whilst the move toward forms of direct public engagement might be regarded as symptomatic of the emergence of affective mode of governance we interpret public ambivalence as a nested set of enthusiasms and anxieties. Accordingly we suggest that public engagement might be re-thought, utilising ambivalence as a creative resource, rather than as the problem. (shrink)

Is nanotechnology-based human enhancement morally permissible? One reason to question such enhancement stems from a concern for preserving our species. It is harder than one might think, however, to explain what could be wrong with altering our own species. One possibility is to turn to the environmental ethics literature. Perhaps some of the arguments for preserving other species can be applied against nanotechnology-based human enhancements that alter human nature. This paper critically examines the case for using two of the strongest (...) arguments in the environmental ethics literature to show that nanotechnology-based human enhancements are impermissible: 1) Our species, like many other naturally occurring species, has aesthetic value. So, nanotechnology-based human enhancements that alter our species should be prohibited. 2) Our species plays valuable ecological roles. Nanotechnology-based human enhancements that alter our species are likely to interfere with our species playing our ecologically valuable roles. So, such enhancements should be prohibited. Neither argument, ultimately, proves conclusive. The paper concludes, however, that considerations underlying both arguments may show us that some nanotechnology-based human enhancements are impermissible. (shrink)

Far-reaching promises made by nanotechnology have raised the question of whether we are on the way to understanding human beings more and more as belonging to the realm of technology. In this paper, an increasing need to understand the technological re-conceptualization of human beings is diagnosed whenever increasingly “technical” interpretations of humans as mechanical entities are disseminated. And this can be observed at present in the framework of nanobiotechnology, a foremost “technical” self-description where a technical language is adopted. The arena (...) in which the decision is made on increasing the use of technological understanding to define mankind will not be found in the surgery room in which one works with implants, nor the NBIC-laboratory, in which “nerve plugs” are supposed to be developed. The thesis of this paper is that such arena is rather related to the manner in which concepts of humanity are associated with it, how we think and talk about ourselves, and which consequences we draw out of it. (shrink)

Food is a big business in the EU and nanofood products are beginning to be placed on the market. It is still unclear whether the absence of minimum regulation at a global level promotes or prevents the growth of a market in nanofood. However, the development of an adequate risk management policy in relation to food safety is a key concern for consumers. Importantly, the European Parliament in its 2009 Resolution on “Legal aspects on nanomaterials” called for more in-depth scientific (...) research on the toxicity of compounds in nanomaterials, and for the adoption of an EU definition of nanomaterials for regulatory purposes. Unfortunately, in 2011, nanotechnology led to inconclusive debates in the context of the revision of Novel Food Regulation. General Food Law applies to nanofood in terms of safety requirements, and specific rules also apply to food contact materials containing nanoparticles as well as to to additives, vitamins and minerals. The EU legislator also introduced mandatory labelling in respect of products derived from nanotechnologies. The legal framework is evolving according to the so-called “incremental approach”, a governance model that creates the risk of fragmentation. But the main problem is the inconsistent definition of the terms “nanotechnology” and “nanomaterials” when looking at the enforcement of regulations and the provision of a wide range of specific tools for different nanofoods: for example the use of positive lists of authorised substances applying only to food contact materials, additives and supplements. This contribution aims to review the regulations in force in respect to nanofood and novel foods and to highlight the problems that are still unresolved. (shrink)

This chapter contains sections titled: Using Nanomaterials Nanotechnology Computing and Robotics Predicting the Future of Technology.

Parallel to the public discussion on the benefits and risks of nanotechnology, a debate on the ethics of nanotechnology has begun. It has been postulated that a new “nano-ethics” is necessary. In this debate, the — positive as well as negative — visionary and speculative innovations which are brought into connection with nanotechnology stand in the foreground. In this contribution, an attempt is made to discover new ethical aspects of nanotechnology in a more systematic manner than has been the case. (...) It turns out that there are hardly any completely new ethical aspects raised by nanotechnology. It is much rather primarily a case of gradual shifts of emphasis and of relevance in questions which, in principle, are already known and which give reason for ethical discussions on nanotechnology. In a certain manner, structurally novel ethical aspects arise through the important role played by visions in the public discourse. New questions are also posed by the fact that previously separate lines of ethical reflection converge in the field of nanotechnology. The proposal of an independent “nano-ethics”, however, seems exaggerated. (shrink)

In this paper we examine the ethical implications of emerging Nanotechnologically Enhanced Combat Systems (or 'NECS'). Through a combination of materials innovation and biotechnology, NECS are aimed at making combatants much less vulnerable to munitions that pose a lethal threat to soldiers protected by conventional armor. We argue that increasing technological disparities between forces armed with NECS and those without will exacerbate the ethical problems of asymmetric warfare. This will place pressure on the just war principles of jus in bello, (...) by encouraging the resort to tactics that either (i) make it more difficult to respect these principles or (ii) directly violate them, by virtue of attacking non-combatants or creating disproportionate numbers of casualties without a clear military goal. (shrink)

Nanotechnology has been proclaimed as a new technology that could bridge the gap between the rich and the poor countries. Indeed many countries in Asia are fast developing their nanotechnological capabilities. However, one needs to take into consideration the role that culture and values play in adoption of nanotechnological policies, keeping in mind that technology and culture are deeply dependent on each other. I offer a criticism of the dependency theory in economic development, which says that there is an unbridgeable (...) divide that the poorer countries cannot cross. As with other powerful technologies, nanotechnology can create as many problems as solutions. I concentrate how insights from the Buddhist tradition, prevalent in Thailand, could illuminate how nanotechnology could be introduced into the lifeworld of a people. (shrink)

In this paper, we respond to a critique by Erik Thorstensen of the ‘Deepening Ethical Engagement and Participation in Emerging Nanotechnologies’ project concerning its ‘realist’ treatment of narrative, its restricted analytical framework and resources, its apparent confusion in focus and its unjustified contextualisation and overextension of its findings. We show that these criticisms are based on fairly serious misunderstandings of the DEEPEN project, its interdisciplinary approachand its conceptual context. Having responded to Thorstensen’s criticisms, we take the opportunity to clarify (...) and develop our approach to narrative. We articulate the need for novel, theoretically robust approaches to the formation of public attitudes which transcend the limitations of both survey-based approaches—which remain wedded to methodological individualism and which presume that individuals hold distinct and relatively stable attitudes and preferences—and interactionist approaches to public talk, which focus too strongly on individuals-in-interaction as reasoning agents and which ignore the constitutive role of culture and discourse in the formation of public opinion. We suggest that our use of narrative can help to better understand the process through which public attitudes to emerging technology develop out of interactive an engagement with wider cultural arguments and accounts of science and technology. We finish by pointing to parallel developments in social thought—from Charles Taylor’s treatment of social imaginaries to recent developments in post-Bourdieuian cultural sociology—as related projects in understanding the cultural resources and grammars that provide the conceptual infrastructure for modern social life. (shrink)

Nanotechnology is a subject about which we know less than we should, but probably more than we think we do at first glance. Like Defense Secretary Donald Rumsfeld's “known unknowns,” we have learned enough to know what we should be concerned with. Glimmers of risk cropped up recently when German authorities recalled a bathroom cleansing product, “MagicNano,” that purported to contain nanosized particles and was on the market for only three days. More than one hundred people suffered severe respiratory problems (...) – six of whom were hospitalized with pulmonary edema. Although a subsequent analysis of MagicNano found that the nanoliquid ingredient morphed in the production into “supersized” particles, the recall nonetheless turned a white hot spotlight on the risk of NSPs. Latching onto the risks posed to workers producing materials using nanotechnology, the Washington Post has labeled nanotechnology a “seat-of-thepants occupational health experiment.”. (shrink)

The development of ever smaller integrated circuits at the sub-micron and nanoscale—in accordance with Moore’s Law—drives the production of very small tags, smart cards, smart labels and sensors. Nanoelectronics and submicron technology supports surveillance technology which is practically invisible. I argue that one of the most urgent and immediate concerns associated with nanotechnology is privacy. Computing in the twenty-first century will not only be pervasive and ubiquitous, but also inconspicuous. If these features are not counteracted in design, they will facilitate (...) ubiquitous surveillance practices which are widely available, cheap, and intrusive. RFID technology is an instructive example of what nanotechnology has in store for privacy. (shrink)

Lately, nanotechnology has become one of the main topics in the debates regarding what has been called the _Next Industrial Revolution_ within what are known as _emergent technologies_. This paper contains a comparative analysis of the different philosophical groundings, arguments and principles invoked in the official ethical approaches proposed by each of two of the main Western communities. By _official ethical approaches_ or _official positions_ we mean the opinions officially expressed by the government institutions about how ethical considerations prompted by (...) nanotechnologies should be tackled. The analysis is based, then, on the official points of view, expressed through two documents, namely two official releases issued by governmental offices or institutions in both communities, Europe and the United States of America, and considered by the authors as representative of the official opinions of the governmental institutions in each society. (shrink)

By exploring whether nanotechnologies have the potential to generate green innovations, we consider the paradox between the negative and positive side-effects that could come with the development of nanotechnologies. Starting from the conceptual framework of green product innovation, the potential green innovation activity of more than 14,000 firms of the nanotech sector is investigated. Using a query-search method, their patenting activity is explored. Results first show that there is an increasing trend toward the creation of fundamental green knowledge (...) by firms involved in nanotechnologies; second, they demonstrate that energy efficiency is the main driver of green knowledge creation in the sector and third they reveal the main characteristics of nanotech firms creating green knowledge. Beyond their contribution to the debate between positive and negative outcomes of nanotechnology developments, these results also enrich the conceptual framework of green product innovation—a key route to achieving sustainability at the same time as growth. (shrink)

This introduction provides background information on the emerging field of nanotechnology and its ethical dimensions. After defining nanotechnology and briefly discussing its status as a discipline, about which there exists a meta-controversy, this introduction turns to a discussion of the status of nanoethics and lays out particular issues of concern in the field, both current and emerging.

Nanotechnology is science and engineering resulting from the manipulation of matter’s most basic building blocks: atoms and molecules. As such, nanotechnology promises unprecedented control over both the materials we use and the means of their production. Such control could revolutionize nearly every sector of our economy, including medicine, defense, and energy. Despite the relatively recent emergence of this field, it already enjoys generous federal funding and enthusiastic media coverage. The tenor of discourse on nanotechnology is changing, however, as the voices (...) of critics begin to sound about a host of concerns ranging from the societal impacts of improving human performance to the specter of environmental devastation and human disease. (shrink)

This paper reflects on the change of relations among participants in nanotechnology governance through their participation in governance processes such as stakeholder dialogues. I show that policymaking in practice—that is, the practice of coming and working together in such stakeholder dialogues—has the potential for two-fold performative effects: it can contribute to the development of trust and mutual responsibility on the part of the involved actors, and it may bring about effects on the formation of boundaries of what is sayable and (...) thinkable in nanotechnology governance. Three vignettes about the work of the German NanoKommission indicate the development of new relations of trust, recognition and mutual responsibility among actors. It is concluded that governance in practice can assemble new collectives in which relations of trust are the glue holding the complex structure together. While such a consensus-based progress may be favourable for smooth technology development, it can be considered problematic if evaluated against the ideals of deliberative democracy, which often form the premises on which public engagement is based. Stakeholder forums were set in place with the intention of including various actors, but this is Janus-faced: if a dialogue becomes encapsulated in new governance networks, new exclusions can arise. For example, a policing of which information is released to a wider audience can occur. (shrink)

This article contributes to the debate on governance of emerging technologies, focusing in particular on the international level and taking into account the fact that these technologies are developed through a common effort of different stakeholders including governments, research communities, industry and civil society actors. These issues are explored from the perspective of communitarian ethical criticism of liberal social contract thinking, in order to enhance visibility of the influence collective non-state actors exercise on the development of these technologies. In particular, (...) the effect of different values in the discussion on emerging technologies on the perceived governance options is explored. A paradigm shift from defensive values such as security, risk and human rights to more optimistic values like peace, justice and integrity of creation is proposed and discussed. (shrink)

Nanotechnology has been a focal area of United States (US) Science and Technology policy since President Clinton's administration. The Unites States is investing more funds in nanotechnology research and development than any other nation. The US National Laboratory community and Sandia National Laboratories in particular is responding to their country's interest by generating exceptional Nano-based science and technology and focusing these efforts on national security and safety concerns. The United States and others are finding that the technological, safety, ethical, economic, (...) and policy considerations centered on nanotechnology are complex and interconnected. Further, that tomorrow's decision makers need an expanded educational background for them to make optimal choices concerning nanotechnology. Sandia National Laboratories responded to this need by initiating the National Institute for Nanotechnology Engineering (NINE). NINE is prototype educational effort designed to provide an exceptional foundation for the next generation of US nanotechnology decision makers. (shrink)

Nanotechnology, which involves manipulation of matter on a ‘nano’ scale, is considered to be a key enabling technology. Medical applications of nanotechnology are expected to significantly improve disease diagnostic and therapeutic modalities and subsequently reduce health care costs. However, there is no consensus on the definition of nanotechnology or nanomedicine, and this stems from the underlying debate on defining ‘nano’. This paper aims to present the diversity in the definition of nanomedicine and its impact on the translation of basic science (...) research in nanotechnology into clinical applications. We present the insights obtained from exploratory qualitative interviews with 46 stakeholders involved in translational nanomedicine from Europe and North America. The definition of nanomedicine has implications for many aspects of translational research including: fund allocation, patents, drug regulatory review processes and approvals, ethical review processes, clinical trials and public acceptance. Given the interdisciplinary nature of the field and common interest in developing effective clinical applications, it is important to have honest and transparent communication about nanomedicine, its benefits and potential harm. A clear and consistent definition of nanomedicine would significantly facilitate trust among various stakeholders including the general public while minimizing the risk of miscommunication and undue fear of nanotechnology and nanomedicine. (shrink)

Because of the overly market-oriented way in which technological development is carried out, there is a great amount of hubris in regard to how scientific and technological achievements are used in society. There is a tendency to exaggerate the potential commercial benefits and willfully neglect the social, cultural, and environmental consequences of most, if not all innovations, especially in new fields such as nanotechnology. At the same time, there are very few opportunities, or sites, for ensuring that nanotechnology is used (...) justly and fairly, or for that matter, contribute to alleviating any of the wide variety of injustices that exist in the world. Most of the public authorities responsible for the development and application of science and technology are uninterested and unwilling to “assess” the implications of nanotechnology, and there are few, if any spaces in the broader culture for assessment to take place. Within the various “social movements” that are, in one way or another, concerned with issues of global justice, there is as yet little interest in nanotechnology. By examining the relations between nanotechnology and the emerging movement for global justice this article attempts to understand the enormous gap between the potential for science and technology to do good and the actual ways in science and technology get developed, and what, if anything, might be done to help close the gap in relation to nanotechnology, so that it might better be able to contribute to global justice. (shrink)

The present paper contributes to a growing body of philosophical, sociological, and historical analyses of recent nanoscale science and technology. Through a close examination of the origins of contemporary nanotech efforts, their ambitions, and strategic uses, it also aims to provide the basis for a critical theory of emerging technologies more generally, in particular in relation to their alleged convergence in terms of goals and outcomes. The emergence, allure, and implications of nanotechnology, it is argued, can only be fully appreciated (...) if one looks beyond its immediate technical and scientific payoffs to its infrastructural and ideological aspects. While nanotechnology aims to reshape the world 'atom by atom', its most tangible result so far has been the profound effect it has had on the organization of science-at-large, not least as the result of a thorough reshaping of the 'soft' funding infrastructure that places signifi cant constraints on the pursuit of long-term scientific research programmes. The paper concludes by noting a persistent, and perhaps deepening, gap between the utopian visions of some of nanotechnology's most vocal proponents and the realities of contemporary nanotechnological practice, which continue to be marked by global inequities. (shrink)

Expectations play a central role in understanding scientific and technological changes. Future-oriented representations are also central with regard to nanotechnologies as they can guide policy activities, provide structures and legitimation, attract different interests, focus policy-makers’ attention and foster investments for research. However, the emphasis on future scenarios tends to underrate the complexity of the challenges of the present market of nanotechnologies by flattening them under the needs and promises of scientific research. This is particularly apparent if we consider (...) the viewpoint of the regulator who faces two different ranges of problems with regard to the market and research and is expected, simultaneously, to manage two different types of regulatory instruments, pursuing at the same time the same goals. Instead, by favoring only the future scenarios, the regulator runs the risk of abruptly shifting from more flexible and elastic tools to forms of hard legislation, wasting, thus, the resources of the soft-regulation, in particular those of self-regulation. By referring primarily to the European context, human rights, also thanks to their normative structure of principles, can help in strengthening both the legislation needed for regulating the present market and the soft instruments needed for steering research and for fostering the stakeholders’ participation without sacrificing the coherence of the regulatory response. (shrink)

The revolutionary Feynman vision of a powerful and general nanotechnology, based on nanomachines that build with atom-by-atom control, promises great opportunities and, if abused, great dangers. This vision made nanotechnology a buzzword and launched the global nanotechnology race. Along the way, however, the meaning of the word has shifted. A vastly broadened definition of nanotechnology (including any technology with nanoscale features) enabled specialists from diverse fields to infuse unrelated research with the Feynman mystique. The resulting nanoscaletechnology funding coalition has obscured (...) the Feynman vision by misunderstanding its basis, distrusting its promise, and fearing that public concern regarding its dangers might interfere with research funding. In response, leaders of a funding coalition have attempted to narrow nanotechnology to exclude one area of nanoscale technology—the Feynman vision itself. Their misdirected arguments against the Feynman vision have needlessly confused public discussion of the objectives and consequences of nanotechnology research. (shrink)

The emergence of nanotechnology, with all its promises of economic, social, and medical benefits, along with dire predictions of environmental, health, and safety threats, has occasioned an active debate in the Science and Technology Studies field, in which we have seen five distinct conversations that frame the discussion. The topical threads include ethics, regulation, opportunities and threats including utopian/dystopian visions of the future, public perception, public participation. These conversational distinctions are not absolutes with firm borders as they clearly overlap at (...) many points. Nonetheless, common to all is a strong sense that control and consequence are significant problems that have yet to be addressed adequately by the promoters of nanotechnology. A final section addresses articles on nanotechnology that exemplify the social construction theory of technology. We include herein a selective summary of this recent body of science, technology, and society (STS) journal literature focused on the social and ethical interactions of nanotechnology (SEIN) that has emerged in the last few years. The intent is not to be encyclopedic in coverage, but rather to seek to understand, in a general way, the key issues and concepts STS scholars are discussing. It is clear that STS-oriented scholars are well poised to grapple explicitly with the cultural, socio-political, and ethical dimensions of nanotechnology. Drawing on understandings of earlier socio-technical areas of interest and concern—nuclear power, genetically modified organisms, the human genome—such scholars have moved well beyond the questions of whether and where nanotechnology intersects society. More important is their effort to seek an understanding in depth of exactly how they are socio-politically, culturally, and ethically interconnected. In doing so, SEIN studies have at the same time become increasingly diverse and more sophisticated and mature over the course of the past decade. Scholars have quite rightly recognized the inadequacies of blanket ideas of moratoria versus non-regulatory environments, utopian versus dystopian futures, and whether or not the public has a role to play in nanotechnology decision making. Rather, a more sophisticated, often case specific, flexible understanding of the societal context of a given issue or concern is called for. (shrink)

Two criteria are proposed for characterizing the diverse and not yet perspicuous relations between nanotechnology and nature. They assume a concept of nature as that which is not made by human action. One of the criteria endorses a distinction between natural and artificial objects in nanotechnology; the other allows for a discussion of the potential nanotechnological modification of nature. Insofar as current trends may be taken as indicative of future development, nanotechnology might increasingly use the model of nature as a (...) point of orientation, while many of its products will continue to be clearly distinguished from nature. (shrink)

In this paper I focus on the question of whether nanotechnology is giving rise to new ethical problems rather than merely to new instances of old ethical problems. Firstly, I demonstrate how important it is to make a general distinction between new ethical problems and new instances of old problems. Secondly, I propose one possible way of interpreting the distinction and offer a definition of a “new ethical problem”. Thirdly, I examine whether there is good reason to claim that nanotechnology (...) is giving or will give rise to new ethical problems. My conclusion is that there are no new ethical problems in nanotechnology but merely new occurrences of certain well-known types of ethical problems. Fourthly, I consider three arguments by van de Poel (NanoEthics 2:25–28, 2008) which contradict my conclusion. I argue that my negative conclusion is consistent with the claim that certain ethical issues arising in nanotechnology may require new normative standards or new analytical tools. I conclude that it is likely that a number of ethical issues arising in nanotechnology will have a considerable impact on our ethical theories and values – and that ethical reflection on nanotechnology will be one of the mother lodes of future ethical research – in spite of the fact that no ethical problem in nanoethics will actually be “new”. (shrink)

This article argues that advances in nanotechnology in general, and lab-on-chip technology in particular, have the potential to benefit the developing world in its quest to control risks to human health and the environment. Based on the “risk society” thesis of Ulrich Beck, it is argued that the developed world must realign its science and technology policy priorities to meet some of the most pressing needs of humanity.

Ongoing research in nanotechnology promises both innovations and risks, potentially and profoundly changing the world. This book helps to promote a balanced understanding of this important emerging technology, offering an informed and impartial look at the technology, its science, and its social impact and ethics. Nanotechnology is crucial for the next generation of industries, financial markets, research labs, and our everyday lives; this book provides an informed and balanced look at nanotechnology and its social impact Offers a comprehensive background discussion (...) on nanotechnology itself, including its history, its science, and its tools, creating a clear understanding of the technology needed to evaluate ethics and social issues Authored by a nanoscientist and philosophers, offers an accurate and accessible look at the science while providing an ideal text for ethics and philosophy courses Explores the most immediate and urgent areas of social impact of nanotechnology. (shrink)

ABSTRACT Nanotechnologies are an expression of the human ability to control and manipulate matter on a very small scale. Their use will enable an even and constant monitoring of human organisms, in a new and perhaps less invasive way. Debates at all levels – national, European and international – have pointed out the common difficulty of giving a complete, clear definition of nanotechnologies. This is primarily due to the variety of their components, to the fact that there is (...) not just one technology but several. The most significant medical applications of nanotechnologies are in the diagnostic and the therapeutic fields, eg biosensors and molecular imaging, providing diagnosis and drug delivery with no invasive methods involved. Like any other emerging field, such technologies imply new possibilities for improving health but, on the other hand, they are still at an experimental stage and therefore should be implemented under rigorous safety testing before going on general release. For this purpose, the ethical, legal and social implications (ELSI) of nanotechnologies have been elaborated by study groups, in order to develop solutions before the results of the tests are diffused into medical practice. The aim of this paper is to define some of the ethical issues concerning biomedical applications and to evaluate whether there is a need for new or additional guidelines and regulations. (shrink)

The presence of nanotechnologies grew and spread throughout Latin America during the first decade of the 21st century. Science and Technology policies have played an important role in the performance of these new technologies. Various international institutions, such as the World Bank, the Organization for Economic Co-operation and Development, and the Organization of American States promoted similar Science and Technology policies, and included nanotechnology as a priority area. This article shows the role of these Science and Technology policies in (...) the promotion of specific objectives and the gap that was left due to the failure to incorporate an examination of the potential risks to health and environment, not to mention other labor-related effects. The omission of matters relevant to workers and consumers by these institutions led to a distancing from organized civil society. (shrink)

Modern microscopes create a capacity to see and act at the scale where unassisted human senses are powerless. Images of nanoscale phenomena represent a world that effectively intervenes in human life while remaining distant and ineffable. This combination of an unbridgeable distance between man and technology with a real power of the latter over the human condition is characteristic, not only of nanotechnology, but also of the theology of sacred icons that mediate in the knowledge of divine reality. We draw (...) an anthropological analogy between nanotechnological images and sacred icons, and we employ it to analyze the functioning of such images in society. The questions that we study include: a) the art of mediation in representing the ineffable and its necessity; b) the effects provoked by such images; c) primitive comprehension of nanoscale images. This work has repercussions for a wide variety of disciplinary accounts and practices, from the anthropologist and the philosopher to the laboratory scientist, the art critic, and the engineer who conceives and designs nanoscale instruments. (shrink)

Nanotechnology: Considering the Complex Ethical, Legal, and Societal Issues with the Parameters of Human Performance Content Type Journal Article Pages 265-275 DOI 10.1007/s11569-008-0047-6 Authors Linda MacDonald Glenn, Albany Medical College/Center Alden March Bioethics Institute Albany NY 12208 USA Jeanann S. Boyce, Montgomery College Dept. of Computer Science and Business 7600 Takoma Avenue Takoma Park MD 20912 USA Journal NanoEthics Online ISSN 1871-4765 Print ISSN 1871-4757 Journal Volume Volume 2 Journal Issue Volume 2, Number 3.

"Public engagement in science" is one of the buzzwords that, since 2000, has been used in nanotechnology programs. To what extent does public engagement disrupt the traditional relations between science and the public? This paper briefly contrasts the traditional model of science communication - the diffusionist model - that prevailed in the twentieth century and the new model - the participatory model - that tends to prevail nowadays. Then it will try to disentangle the assumptions underlying the public dialogue initiated (...) about nanotechnology, and conclude that nanotechnology actually develops a managerial model of society. (shrink)

The demonstration that dendritic cell (DC)‐derived exosomes can be exploited for targeted RNAi delivery to the brain after systemic injection provides the first proof‐of‐concept for the potential of these naturally occurring vesicles as vehicles of drug delivery. As well as being amenable to existing in vivo targeting strategies already in use for viruses and liposomes, this novel approach offers the added advantages of in vivo safety and low immunogenicity. Fulfilment of the potential of exosome delivery methods warrants a better understanding (...) of their biology, as well as the development of novel production, characterisation, targeting and cargo‐loading nanotechnologies. Ultimately, exosome‐mediated drug delivery promises to overcome important challenges in the field of therapeutics, such as delivery of drugs across otherwise impermeable biological barriers, such as the blood brain barrier, and using patient‐derived tissue as a source of individualised and biocompatible therapeutic drug delivery vehicles. (shrink)

In this paper, the public view of nanotechnology and its applications in medicine, agriculture and industry is evaluated in the mega cities of Iran. Data from 683 individuals in public places provided the first civic perception of nanotechnology in Iran. Quantitative statistical analysis on positive or negative points of view demonstrated that Iranian people had general positive opinions on nanotechnology and its application in medicine. They believed that nanomedicine can significantly improve the current methods used in disease treatments, especially for (...) cancer therapy. In general, the responders believed that they would easily accept the use of nanotechnology products and would like increased financial support of the government on nanomedicine and nanotechnology research fields and they showed little anxiety about the possible risks. According to our statistical analysis, three individual characteristics age, education level and career had a direct correlation with the knowledge level of Iranian people on nanotechnology in the mega cities of Iran. (shrink)

This book charts the development of nanotechnology in relation to society from the early years of the twenty-first century. It offers a sustained analysis of the life of nanotechnology, from the laboratory to society, from scientific promises to societal governance, and attempts to modulate developments.

Risk management of nanotechnology is challenged by the enormous uncertainties about the risks, benefits, properties, and future direction of nanotechnology applications. Because of these uncertainties, traditional risk management principles such as acceptable risk, cost–benefit analysis, and feasibility are unworkable, as is the newest risk management principle, the precautionary principle. Yet, simply waiting for these uncertainties to be resolved before undertaking risk management efforts would not be prudent, in part because of the growing public concerns about nanotechnology driven by risk perception (...) heuristics such as affect and availability. A more reflexive, incremental, and cooperative risk management approach is required, which not only will help manage emerging risks from nanotechnology applications, but will also create a new risk management model for managing future emerging technologies. (shrink)

This book features the contribution of major European research projects on the governance and ethics of Nanotechnology. They focus on the responsible development of nanotechnology and on the understanding of public debate.

This analysis of Mexico’s nanotechnology policies utilizes indicators developed by the Organization for Economic Co-operation and Development, which in 2008 conducted a pilot survey comparing the nanotechnology policies of 24 countries. In this paper, we apply the same questionnaire to the Mexican case, adding business information derived from the National Institute of Statistics and Geography survey on nanotechnologies, also an OECD instrument.

When philosophers participate in the interdisciplinary ethical, environmental, economic, legal, and social analysis of nanotechnologies, what is their specific contribution? At first glance, the contribution of philosophy appears to be a clarification of the various moral and ethical arguments that are commonly presented in philosophical discussion. But if this is the only contribution of philosophy, then it can offer no more than a stalemate position, in which each moral and ethical argument nullifies all the others. To provide an alternative, (...) we must analyze the reasons behind the prevailing individual and cultural relativism in ethics. The epistemological investigation of this stalemate position will guide us to the core problem of the relation between theory and action . The stalemate can be overcome from a pragmatic philosophical standpoint, which combines epistemology, philosophy of language—that is, the philosophy of speech acts—and practical reasoning—that is, reasoning about decision-making . From this philosophical standpoint, it will be possible to show how philosophy can accompany and support the development of nanotechnologies. (shrink)

The European Union is strategically committed to the development of nanotechnology and its industrial exploitation. However, nanotechnology also has the potential to disrupt human health and the environment. The EU claims to be committed to the safe and responsible development of nanotechnology. In this sense, the EU has become the first governing body in the world to develop nanospecific regulations, largely due to legislative action taken by the European Parliament, which has compensated for the European Commission’s reluctance to develop special (...) regulations for nanomaterials. Nevertheless, divergences aside, political bodies in the EU assume that nanotechnology development is controllable and take for granted that both the massive industrial use of nanomaterials and a high level of environmental and health protection are compatible. However, experiences such as the European controversy over agri-food biotechnology, which somewhat delegitimized the regulatory authority of the EU over technological safety and acceptability, arguably show that controllability assumptions are contestable on the grounds of alternative socio-economic and cultural preferences and values. Recently developed inclusive governance models on safety and innovation, such as “Responsible Research and Innovation”, widely claim that a diversity of considerations and issues are integrated into R&D processes. Even so, the possibility of more radically alternative constitutions of socio-technical safety seems to be seriously limited by the current ideology of innovation and economic imperatives of the global, knowledge-based, capitalist economy. (shrink)

This contribution discusses the United Kingdom (UK) government’s regulatory activities related to nanotechnological development. The central question is what other prudent public regulation can learn from the UK government’s regulatory strategy, its regulatory attitude and its large variety of regulatory measures. Other public regulators can learn from the interactive and integrative UK regulatory approach. They can also draw lessons from the critique on the UK government’s regulatory attitude and its problems to cope with specific nanotechnological challenges. These lessons are based (...) on an evaluation of the UK government’s regulatory activities from the viewpoint of prudent regulation. The notion of responsive regulation, which provides basic ideas for the evaluation methodology, refers to a view on prudence that focuses on moral constitutional values. Interestingly, a similar view on prudence has been discussed in nanoethics. (shrink)

Although many active scientists deplore the publicity about Drexler's futuristic scenario, I will argue that the controversies it has generated are very useful, at least in one respect. They help clarify the metaphysical assumptions underlying nanotechnologies, which may prove very helpful for understanding their public and cultural impact. Both Drexler and his opponents take inspiration from living systems, which they both describe as machines. However there is a striking contrast in their respective views of molecular machineries. This paper based (...) on semipopular publications is an attempt to characterize the rival models of nanomachines and to disentangle the worldviews underpinning the uses of biological reference on both sides. Finally, in an effort to point out the historical roots of the contrast in the concepts of nanomachines, I raise the question of a divide between two cultures of nanotechnology. (shrink)

In continuing news, there is a growing debate on whether current laws and regulations, both in the US and abroad, need to be strengthened as they relate to nanotechnology. On one side, experts argue that nanomaterials, which are making their way into the marketplace today, are possibly harmful to consumers and the environment, so stronger and new laws are needed to ensure they are safe. On the other side, different experts argue that more regulation will slow down the pace of (...) business and innovation in nanotechnology, or that self-regulation is the answer, or other opposing positions. This paper will draw out the core issues behind the debate and explain that there is more at stake than merely environmental, health and safety worries or business interests, as it first appears. We will also suggest an alternative solution to stricter laws, since stricter laws would face formidable practical challenges, even if they are warranted. (shrink)

As histories of nanotechnology are created, one question arises repeatedly: how influential was Richard Feynman’s 1959 talk, “There’s Plenty of Room at the Bottom”? It is often said by knowledgeable people that this talk was the origin of nanotech. It preceded events like the invention of the scanning tunneling microscope, but did it inspire scientists to do things they would not have done otherwise? Did Feynman’s paper directly influence important scientific developments in nanotechnology? Or is his paper being retroactively read (...) into the history of nanotechnology? To explore those questions, I trace the history of “Plenty of Room,” including its publication and republication, its record of citations in scientific literature, and the comments of eight luminaries of nanotechnology. This biography of a text and its life among other texts enables us to articulate Feynman’s paper with the history of nanotechnology in new ways as it explores how Feynman’s paper is read. (shrink)

This volume shows how nanotechnology takes on a wide range of socio-historically specific meanings in the context of globalization, across multiple localities, institutions and collaborations, through diverse industries, research labs, and government agencies and in a variety of discussions within the public sphere itself. It explores the early origins of nanotechnologies; the social, economic, and political organization of the field; and the cultural and subjective meanings ascribed to nanotechnologies in social settings.

The precautionary principle (PP) is thought by many to be a useful strategy for action and by many others useless at best and dangerous at worst. We argue that it is a coherent and useful principle. We first clarify the principle and then defend it against a number of common criticisms. Three examples from nanotechnology are used; nanoparticles and possible health and environmental problems, grey goo and the potential for catastrophe, and privacy risks generated by nanoelectronics.