“To be the first one.” – On the first Nobel Prize in Physiology or Medicine awarded to Emil von Behring in 1901. The German immunologist Emil von Behring is the first Nobel Prize laureate in physiology or medicine. Behring received the award in 1901 “for his work on serum therapy, especially its application against diphtheria”. Behring's name was strongly connected with progress in the field of diphtheria research through various publications. This study contextualizes the awarding of Behring and shows that (...) not only significant scientific and practical results made him primus inter pares in the eyes of the Nobel committee, but also factors like Behring's representation in the daily press and the broad public interest in diphtheria research. After the beginning of the industrial serum production in 1894, Behring was not only a “visible scientist”, he was also portrayed as the “savior of the children” and so ranked among the “great men” of his era. The paper argues that his public visibility and the popularity of “Behring's Diphtherie-Heilmittel” became a strong argument in favor of Behring during the selection process of the first Nobel laureate. The first part of the paper discusses the Nobel Prize nomination procedure from the views of the scientific community. Drawing on personal papers of the extended Behring Archives, the second part focusses on Behring from a private perspective and sheds light on the meaning and importance of the award for Behring and his family. (shrink)