BackgroundWe conducted a survey to identify what types of health/medical research could be exempt from research ethics reviews in Australia.MethodsWe surveyed Australian health/medical researchers and Human Research Ethics Committee members. The survey asked whether respondents had previously changed or abandoned a project anticipating difficulties obtaining ethics approval, and presented eight research scenarios, asking whether these scenarios should or should not be exempt from ethics review, and to provide comments. Qualitative data were analysed thematically; quantitative data in R.ResultsWe received 514 responses. (...) Forty-three per cent of respondents to whom the question applied, reported changing projects in anticipation of obstacles from the ethics review process; 25% reported abandoning projects for this reason. Research scenarios asking professional staff to provide views in their area of expertise were most commonly exempted from ethics review ; scenarios involving surplus samples and N-of-1 studies were most commonly required to undergo ethics review. HREC members were 26% more likely than researchers to require ethics review. Need for independent oversight, and low risk, were most frequently cited in support of decisions to require or exempt from ethics review, respectively.ConclusionsConsiderable differences exist between researchers and HREC members, about when to exempt from review the research that ultimately serves the interests of patients and the public. It is widely accepted that evaluative research should be used to reduce clinical uncertainties—the same principle should apply to ethics reviews. (shrink)

Pleiotropy, in which one mutation causes multiple phenotypes, has traditionally been seen as a deviation from the conventional observation in which one gene affects one phenotype. Epistasis, or gene–gene interaction, has also been treated as an exception to the Mendelian one gene–one phenotype paradigm. This simplified perspective belies the pervasive complexity of biology and hinders progress toward a deeper understanding of biological systems. We assert that epistasis and pleiotropy are not isolated occurrences, but ubiquitous and inherent properties of biomolecular networks. (...) These phenomena should not be treated as exceptions, but rather as fundamental components of genetic analyses. A systems level understanding of epistasis and pleiotropy is, therefore, critical to furthering our understanding of human genetics and its contribution to common human disease. Finally, graph theory offers an intuitive and powerful set of tools with which to study the network bases of these important genetic phenomena. (shrink)

This paper aims to critique the phenomenon of advanced patient autonomy and choice in healthcare within the specific context of self-testing devices. A growing number of self-testing medical devices are currently available for home use. The premise underpinning many of these devices is that they assist individuals to be more autonomous in the assessment and management of their health. Increased patient autonomy is assumed to be a good thing. We take issue with this assumption and argue that self-testing provides a (...) specific example how increased patient autonomy and choice within healthcare might not best serve the patient population. We propose that current interpretations of autonomy in healthcare are based on negative accounts of liberty to the detriment of a more relational understanding. We also propose that Kantian philosophy is often applied to the healthcare arena in an inappropriate manner. We draw on the philosophical literature and examples from the self-testing process to support these claims. We conclude by offering an alternative account of autonomy based on the interrelated concepts of relationality, care and responsibility. (shrink)

In the current landscape, child care is increasingly being seen as a place for early education, and systems are largely bundling child care in the Early Care and Education sphere through funding and quality measures. As states define school readiness and quality, they often miss critical elements, such as equitable access to quality and cultural traditions. This article provides a summary of the various definitions and structures of child care. It also discusses how the current child care policy conversation can (...) and ought to be infused with a framework grounded in the context of institutional racism and trauma. Models and examples will explore the differences between state government regulations, and how those differ than the regulation and structure of child care in Indian Country. (shrink)

“Our later and more critical philosophies are mere fads and fancies compared with this natural mother-tongue of thought”, says William James in his lecture on common sense. The deep bond connecting language, common sense and nature is also one of the main concerns of the later Wittgenstein. The aim of this paper is to compare the two philosophers in this respect, particularly focusing on James’ Pragmatism and on Wittgenstein’s On Certainty. Similarities, but also differences, will be highlighted. A further element (...) will be offered by the analysis of a fragment of Wittgenstein’s Nachlass, which anticipates his image of the river-bed of thought through the critique of James’ stream of thought. By means of this comparison, I will question Wittgenstein’s explicit refusal of pragmatism. I will argue that his late philosophy can be said to be even more pragmatist than James’, in that it delineates a conception of the common sense certainties which shape our Weltbild (world-picture) as practically, and not merely epistemically, connected to our life. (shrink)

Everyday resistance is about the many ways people undermine power and domination through their routine and everyday actions. Unlike open rebellions or demonstrations, it is typically hidden, not politically articulated, and often ingenious. But because of its disguised nature, it is often poorly understood as a form of politics and its potential underestimated. Conceptualizing Everyday Resistance presents an analytical framework and theoretical tools to understand the entanglements of everyday power and resistance. These are applied to diverse empirical cases including queer (...) relationships in the context of heteronormativity, Palestinian daily life under military occupation, workplace behaviors under office surveillance, and the tactics of fat acceptance bloggers facing the War against obesity. Johansson and Vinthagen argue that everyday resistance is best understood by accounting for different repertoires of tactics, relations between actors, and struggles around constructions of time and space. Through a critical dialogue with the work of James C. Scott, Michel de Certeau, and Asef Bayat, they aim to reconstruct the field of resistance studies, expanding what counts as resistance and building systematic analysis. Conceptualizing Everyday Resistance offers researchers and students from different theoretical and empirical backgrounds, an essential overview of the field and a creative framework that illuminates the potential of all people to transform society. (shrink)

How can we explain the structure of perceptual experience? What is it that we perceive? How is it that we perceive objects and not disjoint arrays of properties? By which sense or senses do we perceive objects? This book investigates Aristotle's views on these and related questions.

Recent scandals allegedly linked to CEO compensation have brought executive compensation and perquisites to the forefront of debate about constraining executive compensation and reforming the associated corporate governance structure. We briefly describe the structure of executive compensation, and the agency theory framework that has commonly been used to conceptualize executives acting on behalf of shareholders. We detail some criticisms of executive compensation and associated ethical issues, and then discuss what previous research suggests are likely intended and unintended consequences of some (...) widely proposed executive compensation reforms. We explicitly discuss the following recommendations for reform: require greater independence of compensation committees, require executives to hold equity in the corporation, require greater disclosure of executive compensation, increase institutional investor involvement in corporate governance (including executive compensation), and require firms to expense stock options on their income statements. We provide a brief summary discussion of ethical issues related to executive compensation, and describe possible future research. (shrink)

Although the subject matter of this Element is properties, do not expect in-depth introductions to the various views on properties 'on the market'. Instead, here that subject matter is treated meta-philosophically. Rather than ask and try to answer a question like do properties exist? this Element asks what reasons one might have for thinking that properties exist, what counts as solving that problems, as well as how we ought to proceed when trying to find out if properties exist. As it (...) turns out, these questions and their answers are all intricately intertwined. Theory comparison and theory evaluation is in other words tricky. Do properties exist? After reading this Element all we can say is therefore this: that depends. (shrink)

This paper argues that the function of moral education in the biomedical context should be exactly the same as in a general, philosophical framework: it should not provide ready-to-use kits of moral principles; rather, it must show the history, epistemology and conceptual structure of moral theories that would enable those who have to make decisions to be as informed and as responsible as possible. If this complexity cannot be attained, an incomplete product—i.e. bioethics or bioethical principles—should not be seen as (...) a viable substitute. This theoretical position is subsequently illustrated by a case study involving research ethics committees. It is argued that within these committees, that are carefully formed multidisciplinary bodies, what makes competent decision-making possible is not a bioethical theory, nor even a sound philosophical ethics, but the dynamics of the discussion of a number of experts coming from different disciplines. This multidisciplinary expertise is necessary and sufficient to undertake the challenges of complex decisions in the biomedical context. (shrink)

In this 2002 book, Anna Elisabetta Galeotti examines the most intractable problems which toleration encounters and argues that what is really at stake is not religious or moral disagreement but the unequal status of different social groups. Liberal theories of toleration fail to grasp this and consequently come up with normative solutions that are inadequate when confronted with controversial cases. Galeotti proposes, as an alternative, toleration as recognition, which addresses the problem of according equal respect to groups as well (...) as equal liberty to individuals. She offers an interpretation that is both a revision and an expansion of liberal theory, in which toleration constitutes an important component not only of a theory of justice, but also of the politics of identity. Her study will appeal to a wide range of readers in political philosophy, political theory, and law. (shrink)

In this paper, I argue for three theses. First, that the problem of Deep Disagreement is usefully understood as an instance of the skeptical Problem of the Criterion. Second, there are structural similarities between proposed optimistic answers to deep disagreement and the problem of the criterion. Third, in light of these similarities, there are both good and bad consequences for proposed solutions to the problem of deep disagreement.

The book is aimed at general readers with an interest in the mind and neuroscience, as well as a wide range of scientists whose work is related to the rapidly...

The focus of this paper is the discussion between supporters of the intentional account of SD and supporters of the causal account. Between these two options the author argues that SD is the unintentional outcome of intentional steps taken by the agent. More precisely, she argues that SD is a complex mixture of things that we do and that happen to us; the outcome is however unintended by the subject, though it fulfils some of his practical, though short-term, goals. In (...) her account, SD is produced after a fashion similar to those beneficial social phenomena which serve some collective purpose, are the product of human action, but not of human design, such as money, language and many social conventions; and similarly SD can be accounted by invisible hand explanation. The paper will critically analyze both the intentional and the causal accounts, and then present the invisible hand explanation which avoids the most puzzling aspect of the intentional view, while keeping the distinctiveness of SD in the realm of motivated irrationality. A brief discussion of the issue of responsibility for SD will conclude the paper. (shrink)

The human imagination manifests in countless different forms. We dream the possible and the impossible. How do we do this so effortlessly? Why did the capacity for imagination evolve and seem to manifest uniquely in our species? This handbook reflects on such questions by collecting perspectives from leading experts. It showcases a rich and detailed analysis on how the imagination is understood across several disciplines of study, including anthropology, archaeology, medicine, neuroscience, psychology, philosophy and the arts. An integrated theoretical-empirical-applied picture (...) of the field is presented, which informs researchers, students and practitioners about the issues of relevance across the board. With each chapter, human imagination is explained - what it entails, how it evolved, and why it singularly defines us as a species. (shrink)

Diogenes’s exchange with Cicermos the Olympic pankratist is unusual in that it is both a dialectical exchange and is successful in changing Cicermos’s mind. Most Cynic rhetoric is physical or gestural and more often alienates than convinces. The puzzling difference is explained by the rhetorical choices Diogenes makes with his uniquely receptive audience.

Why We Argue : A Guide to Political Disagreement in an Age of Unreason presents an accessible and engaging introduction to the theory of argument, with special emphasis on the way argument works in public political debate. The authors develop a view according to which proper argument is necessary for one's individual cognitive health; this insight is then expanded to the collective health of one's society. Proper argumentation, then, is seen to play a central role in a well-functioning democracy. Written (...) in a lively style and filled with examples drawn from the real world of contemporary politics, and questions following each chapter to encourage discussion, Why We Argue reads like a guide for the participation in, and maintenance of, modern democracy. An excellent student resource for courses in critical thinking, political philosophy, and related fields, Why We Argue is an important contribution to reasoned debate. What's New in the Second Edition: Updated examples throughout the book, including examples from the 2016 U.S. election and first years of the Trump presidency; Expanded coverage of dialectical fallacies, including coverage of new types of fallacies and of sites where such fallacies thrive ; Revised For Further Thought questions and definitions of Key Terms, included at the end of each chapter; The addition of five new chapters: Deep Disagreement Argument by Analogy Argument between the Ads The Owl of Minerva Argumentative Responsibility and Repair. (shrink)

Research integrity climate is an important factor that influences an individual’s behavior. A strong research integrity culture can lead to better research practices and responsible conduct of research. Therefore, investigations on organizational climate can be a valuable tool to identify the strengths and weaknesses of each group and develop targeted initiatives. This study aims to assess the perceptions on integrity climate in three universities in Hungary. A cross-sectional study was conducted with PhD students, postdocs, and professors from three Hungarian universities. (...) The survey included demographic questions, such as gender, age, scientific field, academic rank, and the Survey of Organizational Research Climate. A total of 432 participants completed the survey. Our results show that postdocs and assistant professors perceived integrity climate more negatively than PhD students and full professors in every survey scale. Contrarily, PhD students perceive more positively than the other groups. Disciplinary differences show that researchers in the Biomedical sciences perceive regulatory bodies to be fairer when evaluating their projects than those in the Natural sciences. Natural sciences also perceive more negatively how the department values integrity when compared to Humanities. Humanities perceive more positively Advisor/Advisee Relations than Biomedical Sciences. Our results suggest that institutions should pay more attention to early career researchers, especially insecure and temporary positions like postdocs and assistant professors. They should provide RCR resources, socialize them in RCR, and set more reasonable expectations. Moreover, department leaders should develop initiatives to foster better integrity climates. (shrink)

A common argument for evidentialism is that the norms of assertion, specifically those bearing on warrant and assertability, regulate belief. On this assertoric model of belief, a constitutive condition for belief is that the believing subject take her belief to be supported by sufficient evidence. An equally common source of resistance to these arguments is the plausibility of cases in which a speaker, despite the fact that she lacks warrant to assert that p, nevertheless attributes to herself the belief that (...) p. In the following, I will outline a variety of ways a speaker may contrastively attribute a belief to herself. In light of what these contrastive statements communicate, cases of attributing beliefs with little or no warrant to oneself offer no substantive counter-example to the evidentialist argument from assertion. (shrink)

Wittgenstein likens philosophy both to an illness and to a therapy. The reflections he dedicates to mental disturbance in On Certainty shed some light on this ambivalence, by pointing at the intertwined themes of common sense, doubt, mistake, reasonableness, and normality. Wittgenstein’s remarks have sometimes been compared to the description of the symptoms of what psychopathologists have called the loss of natural self-evidence, or the loss of common sense. Besides briefly recalling some of the outcomes of this debate in literature, (...) I focus on Wittgenstein’s conception of “hinges”, the basic practical certainties which patients suffering from the loss of common sense seem to lack. By working on this comparison, I offer an interpretation of Wittgenstein’s idea of philosophy that clarifies both its insane and its therapeutic side. (shrink)

: The rights to liberty championed by classical liberal and libertarian theorists may be supported as products of practical reason. The foundations for these rights rest initially on the idea that the separateness of persons is embedded in the circumstances of life that make justice a meaningful concept. We can discover the duties justice imposes […].

Public health raises critical ethics issues and concerns, making public heath ethics an essential topic for students and public health professionals. The 73 chapters in this volume examine public health ethics across a broad range of public health topics both in the U.S. and globally. It is the first ever comprehensive collection devoted to public health ethics.