BackgroundReconciling results obtained using different types of sensory measures is a challenge for autism sensory research. The present study used questionnaire, psychophysical, and neurophysiological measures to characterize autistic sensory processing in different measurement modalities.MethodsParticipants were 46 autistic and 21 typically developing 11- to 14-year-olds. Participants and their caregivers completed questionnaires regarding sensory experiences and behaviors. Auditory and somatosensory event-related potentials were recorded as part of a multisensory ERP task. Auditory detection, tactile static detection, and tactile spatial resolution psychophysical (...) class='Hi'>thresholds were measured.ResultsSensory questionnaires strongly differentiated between autistic and typically developing individuals, while little evidence of group differences was observed in psychophysical thresholds. Crucially, the different types of measures appeared to be largely independent of one another. However, we unexpectedly found autistic participants with larger auditory Tb ERP amplitudes had reduced hearing acuity, even though all participants had hearing acuity in the non-clinical range.LimitationsThe autistic and typically developing groups were not matched on cognitive ability, although this limitation does not affect our main analyses regarding convergence of measures within autism.ConclusionOverall, based on these results, measures in different sensory modalities appear to capture distinct aspects of sensory processing in autism, with relatively limited convergence between questionnaires and laboratory-based tasks. Generally, this might reflect the reality that laboratory tasks are often carried out in controlled environments without background stimuli to compete for attention, a context which may not closely resemble the busier and more complex environments in which autistic people’s atypical sensory experiences commonly occur. Sensory questionnaires and more naturalistic laboratory tasks may be better suited to explore autistic people’s real-world sensory challenges. Further research is needed to replicate and investigate the drivers of the unexpected association we observed between auditory Tb ERP amplitudes and hearing acuity, which could represent an important confound for ERP researchers to consider in their studies. (shrink)

It is common practice in intergenerational justice to set fixed thresholds determining what qualifies as justice. Static definitions of how much and what to save for future generations, however, overestimate human epistemological limits and predictive capacity in regard to uncertainty in social- and ecosystems. Long-term predictions cannot account for the inherent range of contingent variables at play, especially according to contemporary theories of punctuated equilibrium. It is argued that policies deliberately testing ecological limits as currently conceived must be (...) excluded from political calculations to minimize current actions from foreclosing future life quality and options. To better reduce harms to present and future generations and support the stability of just institutions (and the stable environments they depend on) as Rawls and others demand, polities can overcompensate resource allocation to environmental sustainability. Focus on reducing environmental harms benefits both current and future generations, reconciling distributive versus intergenerational justice trade-offs. (shrink)

At present UK Law states that the unborn child only becomes a legal person invested with legal rights and full protections, like other human persons, at birth. This article critiques the present legal position of setting the threshold for legal personality at birth, showing its inconsistencies and fundamentally pragmatic basis. Against this background, it is argued that a principled approach towards unborn life is necessary, which reflects in law the reality that the unborn child is a type of human person (...) deserving protection as it develops through the continuum of human personhood – from embryonic personhood, to infant personhood and ultimately into adult personhood. Human personhood is defined as a union of a material and immaterial self, meaning that at every stage of their development they are never a “potential person,” but rather a “person with potential” even if it is not actualized through miscarriage, premature death, or disability. This moral and philosophical reasoning is what justifies protecting the sanctity of unborn life in law. The rest of the article explores and critiques the alternative static legal threshold for ascribing legal personality, at conception, implantation and viability. Having considered the practical moral, legal and philosophical problems of these alternatives; the final proposal for law reform combines all three of these thresholds in a proposal for a “dynamic” threshold for legal personality commencing at conception, which would render birth as an irrelevant threshold for moral and legal reasoning about the unborn. (shrink)

The concept of empathy describes our capacity to understand the emotions and intentions of others and to relate to our conspecifics. Numerous studies investigated empathy as a state as well as a stable personality trait. For example, recent studies in neuroscience suggest, among other brain areas such as the insula or the ACC, a role of the somatosensory cortices for empathy. Since the classic understanding of the primary somatosensory cortex is to represent touch on the body surface, we here aimed (...) to test whether tactile performance is linked to the personality trait empathy. To test this, we examined the tactile acuity of 95 healthy participants by using a two-point discrimination threshold task at the index fingers. Trait empathy was assessed by employing the interpersonal reactivity index, which measures self-reported empathy with four scales. Results of regression analyses suggested the subscale empathic concern to be positively associated with performance in the tactile acuity task. We discuss this finding in the light of recent studies on empathy and consider possible implications of tactile training to enhance empathy. (shrink)

The Temporal-Order Judgment (TOJ) paradigm has been widely investigated in previous studies as an accurate measure of temporal resolution and sequencing abilities in the millisecond time range. Two auditory TOJ tasks are often used: (1) a spatial TOJ task, in which two identical stimuli are presented in rapid succession monaurally and the task is to indicate which ear received the first stimulus and which ear received the second one ( left-right or right-left ), and (2) a spectral TOJ task, in (...) which two tones of different frequencies are presented asynchronously to both ears binaurally and the task is to report the sequence of these tones ( low-high or high-low ). The previous literature studies conducted on young volunteers indicated that the measured temporal acuity on these two tasks depended on the procedure used. As considerable data are now available about age-related decline in temporal resolution ability, the aim of the present study was to compare in elderly subjects the pattern of performance on these two tasks. A total of 40 normal healthy volunteers aged from 62 to 78 years performed two TOJ tasks. The measurement was repeated in two consecutive sessions. Temporal resolution was indexed by the Auditory Temporal-Order Threshold (ATOT), i.e., the minimum time gap between successive stimuli necessary for a participant to report a before-after relation with 75% correctness. The main finding of the present study was the indication of differences in the elderly in performance on two tasks. In the spatial task, the distribution of obtained ATOT values did not deviate from the Gaussian distribution. In contrast, the distribution of data in the spectral task deviated significantly from the Gaussian and was spread more to the right. Although lower ATOT values were usually observed in Session 2 than in Session 1, such difference was significant only in the spectral task. We conclude that although temporal acuity and sequencing abilities in the millisecond time range are probably based in neuronal oscillatory activity, the measured ATOTs in the elderly seem to be stimulus-dependent, procedure-related, and influenced by the perceptual strategies used by participants. (shrink)

We experience our own body through both touch and vision. We further see that others’ bodies are similar to our own body, but we have no direct experience of touch on others’ bodies. Therefore, relations between vision and touch are important for the sense of self and for mental representation of one’s own body. For example, seeing the hand improves tactile acuity on the hand, compared to seeing a non-hand object. While several studies have demonstrated this visual enhancement of (...) touch effect, its relation to the ‘bodily self’, or mental representation of one’s own body remains unclear. We examined whether VET is an effect of seeing a hand, or of seeing my hand, using the rubber hand illusion. In this illusion, a prosthetic hand which is brushed synchronously—but not asynchronously—with one’s own hand is felt to actually be one’s hand. Thus, we manipulated whether or not participants felt like they were looking directly at their hand, while holding the actual stimulus they viewed constant. Tactile acuity was measured by having participants judge the orientation of square-wave gratings. Two characteristic effects of VET were observed: cross-modal enhancement from seeing the hand was inversely related to overall tactile acuity, and participants near sensory threshold showed significant improvement following synchronous stroking, compared to asynchronous stroking or no stroking at all. These results demonstrate a clear functional relation between the bodily self and basic tactile perception. (shrink)

This paper is concerned with the event-based state and fault estimation problem for a class of linear discrete systems with randomly occurring faults and missing measurements. Different from the static event-based transmission mechanism with a constant threshold, a dynamic event-based mechanism is exploited here to regulate the threshold parameter, thus further reducing the amount of data transmission. Some mutually independent Bernoulli random variables are used to characterize the phenomena of ROFs and missing measurements. In order to simultaneously estimate the (...) system state and the fault signals, the main attention of this paper is paid to the design of recursive filter; for example, for all DETM, ROFs, and missing measurements, an upper bound for the estimation error covariance is ensured and the relevant filter gain matrix is designed by minimizing the obtained upper bound. Moreover, the rigorous mathematical analysis is carried out for the exponential boundedness of the estimation error. It is clear that the developed algorithms are dependent on the threshold parameters and the upper bound together with the probabilities of missing measurements and ROFs. Finally, a numerical example is provided to indicate the effectiveness of the presented estimation schemes. (shrink)

Some patients with damaged striate cortex have blindsight-the ability to discriminate unseen stimuli in their clinically blind visual field defects when forced-choice procedures are used. Blindsight implies a sharp dissociation between visual performance and visual awareness, but signal detection theory indicates that it might be indistinguishable from the behavior of normal subjects near the lower limit of conscious vision, where the dissociations could arise trivially from using different response criteria during clinical and forced-choice tests. We tested the latter possibility with (...) a hemianopic subject during yes-no and forced-choice detection of static and moving targets. His response criterion differed significantly between yes-no and forced-choice responding, and the difference was sufficient to produce a blindsight-like dissociation with bias-sensitive measures of performance. When measured independently of bias, his sensitivity to static targets was greater in the forced-choice than in the yes-no task (unlike normal control subjects), but his sensitivity to moving targets did not differ. Differences in response criterion could therefore account for dissociations between yes-no and forced-choice detection of motion, but not of static pattern. The results explain why patients with blindsight are apparently more often ''aware'' of moving stimuli than of static stimuli. However, they also imply that blindsight is unlike normal vision near threshold, and that pattern- and motion-detection in blindsight may depend on different sets of neural mechanisms during yes-no and forced-choice tests. (shrink)

Human vision supports prediction for moving stimuli. Here we take an individual differences approach to investigate whether there could be a common processing rate for motion-based visual prediction across diverse motion phenomena. Motion Induced Spatial Conflict refers to an incongruity arising from two edges of a combined stimulus, moving rigidly, but with different apparent speeds. This discrepancy induces an illusory jitter that has been attributed to conflict within a motion prediction mechanism. Its apparent frequency has been shown to correlate with (...) the frequency of alpha oscillations in the brain. We asked what other psychophysical measures might correlate positively with MISC frequency. We measured the correlation between MISC jitter frequency and another three measures that might be linked to motion-based spatial prediction. We demonstrate that the illusory jitter frequency in MISC correlates significantly with the accrual rate of the Motion Induced Position Shift effect - the well-established observation that a carrier movement in a static envelope of a Gabor target leads to an apparent position shift of the envelope in the direction of motion. We did not observe significant correlations with the other two measures – the Adaptation Induced Spatial Shift accrual rate and the Smooth Motion Threshold. These results suggest a shared perceptual rate between MISC and MIPS, implying a common periodic mechanism for motion-based visual prediction. (shrink)

Introduction: The potential therapeutic efficacy of real-time fMRI Neurofeedback has received increasing attention in a variety of psychological and neurological disorders and as a tool to probe cognition. Despite its growing popularity, the success rate varies significantly, and the underlying neural mechanisms are still a matter of debate. The question whether an individually tailored framework positively influences neurofeedback success remains largely unexplored.Methods: To address this question, participants were trained to modulate the activity of a target brain region, the visual motion (...) area hMT+/V5, based on the performance of three imagery tasks with increasing complexity: imagery of a static dot, imagery of a moving dot with two and with four opposite directions. Participants received auditory feedback in the form of vocalizations with either negative, neutral or positive valence. The modulation thresholds were defined for each participant according to the maximum BOLD signal change of their target region during the localizer run.Results: We found that 4 out of 10 participants were able to modulate brain activity in this region-of-interest during neurofeedback training. This rate of success is consistent with the neurofeedback literature. Whole-brain analysis revealed the recruitment of specific cortical regions involved in cognitive control, reward monitoring, and feedback processing during neurofeedback training. Individually tailored feedback thresholds did not correlate with the success level. We found region-dependent neuromodulation profiles associated with task complexity and feedback valence.Discussion: Findings support the strategic role of task complexity and feedback valence on the modulation of the network nodes involved in monitoring and feedback control, key variables in neurofeedback frameworks optimization. Considering the elaborate design, the small sample size here tested impairs external validity in comparison to our previous studies. Future work will address this limitation. Ultimately, our results contribute to the discussion of individually tailored solutions, and justify further investigation concerning volitional control over brain activity. (shrink)

In this paper, we study the estimation of motion direction prediction for fast motion and propose a threshold-based human target detection algorithm using motion vectors and other data as human target feature information. The motion vectors are partitioned into regions by normalization to form a motion vector field, which is then preprocessed, and then the human body target is detected through its motion vector region block-temporal correlation to detect the human body motion target. The experimental results show that the algorithm (...) is effective in detecting human motion targets in videos with the camera relatively stationary. The algorithm predicts the human body position in the reference frame of the current frame in the video by forward mapping the motion vector of the current frame, then uses the motion vector direction angle histogram as a matching feature, and combines it with a region matching strategy to track the human body target in the predicted region, thus realizing the human body target tracking effect. The algorithm is experimentally proven to effectively track human motion targets in videos with relatively static backgrounds. To address the problem of sample diversity and lack of quantity in a multitarget tracking environment, a generative model based on the conditional variational self-encoder conditional generation of adversarial networks is proposed, and the performance of the generative model is verified using pedestrian reidentification and other datasets, and the experimental results show that the method can take advantage of the advantages of both models to improve the quality of the generated results. (shrink)

Much leading thought about consciousness in the inter-war period was associated with the British intellectual C. K. Ogden. His International Library of Psychology, Philosophy and Scientific Method included landmark textbooks by major psychologists including Adler, Jung, Koffka, and Piaget. His journal Psyche, included work about Behaviorism, brain chemistry, and essays such as ‘Are we becoming more conscious?’ by literary critic I. A. Richards. The chapter surveys the work from Ogden’s projects which demonstrates the greatest acuity and foresight about questions (...) concerning consciousness which preoccupy us now. It concentrates on Ogden’s other book series – especially To-Day and To-Morrow. Some of the more provocative new thinking about consciousness is to be found among its speculations on the future. In one of the pioneering transhumanist texts in this series, J. D. Bernal’s The World, the Flesh and the Devil invents the electronic cyborg. He imagines increasing longevity by transferring brains to machine hosts; hot-wiring them to instruments providing extra senses – X-ray, chemistry, but above all radio. This would enable them to be in direct wireless contact with everyone else – effectively the internet before the invention of the computer. Such interconnectivity makes imaginable a form of collective consciousness. Such ideas mesh with new thinking about language and criticism; fields in which Ogden and Richards were also pioneers. These writers poised before the threshold of computing thus raise questions which anticipate work in subsequent neuroscience, and also our moment at the dawn of Artificial Intelligence, and the questions that raises about whether consciousness can be extended, synthesized, or indeed detected. (shrink)

SummaryThe outbreak of war in 1914 found Britain unprepared for a lengthy conflict. British science and industry were particularly ill-prepared to meet the demands of static warfare. Within two years, however, mobilization had made appreciable strides, and, as Britain's munitions industries moved from crisis to confidence, Britain's chemical industry was transformed by an arsenal of ‘garrison chemists’, with skills either born of necessity or borrowed from overseas. At the same time, Britain's chemical leadership traced a path that led them (...) from voluntarist to corporate methods, from private to public initiatives, and from individual to collective behaviours. This paper suggests four key stages in this mobilization, and hints at the significance of the war for the emergence of new sub-disciplines, for the careers of chemists, for academic-government relations in research, and for the image, status, and international position of British chemistry on the threshold of the postwar world. (shrink)

Previous studies have demonstrated that orientation-specific deprivation in early life can lead to neural deficits of spatial vision in certain space, and can even result in meridional amblyopia. Individuals with astigmatism are the optimal and natural models for exploring this asymmetric development of spatial vision in the human visual system. This study aims to assess the contrast sensitivity function and EEG signals along two principal meridians in participants with regular astigmatism when being optimal optical corrected. Twelve participants with astigmatism and (...) thirteen participants with were recruited in the current study. CSFs and spatial sweep visual evoked potentials were measured with vertical and horizontal sinewave gratings along two principal meridians monocularly. Area under log CSF, spatial frequency threshold corresponding to 80% contrast gratings, and CSF acuity were calculated from CSF test. In addition, sVEP amplitudes and thresholds were calculated with the recursive least square method. Participants with astigmatism exhibited marked vertical-horizontal resolution disparities even after they were corrected with optimal optical corrections. CSF tests showed that AULCSF along weak meridian was lower than that along strong meridian in both groups. Significant meridional disparity of CSF acuity was also found in both groups. In addition, the MA group showed larger meridional disparity compared to the AST group. Spatial sVEP thresholds also supported the existence of marked meridional disparity. Our results suggest that meridian-specific partial deprivation in early life might lead to monocularly asymmetric development of spatial vision in the human visual system. In terms of application, we tested the feasibility and reliability of adopting psychophysical and EEG scalings to investigate the asymmetric development of spatial vision related to astigmatism. These paradigms are potentially applicable to reduce and even eliminate the meridional disparity in the primary visual cortex by adopting perceptual learning or other vision-related interventions. (shrink)

We elaborate Weiermann-style phase transitions for well-partial-orderings (wpo) determined by iterated finite sequences under Higman-Friedman style embedding with Gordeev’s symmetric gap condition. For every d-times iterated wpo \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\left({\rm S}\text{\textsc{eq}}^{d}, \trianglelefteq _{d}\right)}$$\end{document} in question, d > 1, we fix a natural extension of Peano Arithmetic, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${T \supseteq \sf{PA}}$$\end{document}, that proves the corresponding second-order sentence \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{WPO}\left({\rm (...) S}{\textsc{eq}}^{d}, \trianglelefteq _{d}\right) }$$\end{document}. Having this we consider the following parametrized first-order slow well-partial-ordering sentence \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{SWP}\left({\rm S}\text{\textsc{eq}}^{d}, \trianglelefteq _{d}, r\right):}$$\end{document}\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\left( \forall K > 0 \right) \left( \exists M > 0\right) \left( \forall x_{0},\ldots,x_{M}\in {\rm S}\text{\textsc{eq}}^{d}\right)$$\end{document}\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\left( \left( \forall i\leq M\right) \left( \left| x_{i}\right| 1}$$\end{document} then \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{SWP}\left({\rm S}\text{\textsc{eq}}^{d}, \trianglelefteq _{d},r \right) }$$\end{document} is not provable in T.Moreover, by the well-known proof theoretic equivalences we can just as well replace T by PA or ACA0 and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\Delta _{1}^{1}\sf{CA}}$$\end{document}, if d = 2 and d = 3, respectively.In the limit case d → ∞ we replaceEFA-provably computable reals r by EFA-provably computable functions \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${f: \mathbb{N} \rightarrow \mathbb{R}_{+}}$$\end{document} and prove analogous theorems. (In the sequel we denote by \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{R}_{+}}$$\end{document} the set of EFA-provably computable positive reals). In the basic case T = PA we strengthen the basic phase transition result by adding the following static threshold clause\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{SWP}\left({\rm S}\text{\textsc{eq}}^{2}, \trianglelefteq _{2}, 1\right)}$$\end{document} is still provable in T = PA (actually in EFA). Furthermore we prove the following dynamic threshold clauses which, loosely speaking are obtained by replacing the static threshold t by slowly growing functions 1α given by \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${1_{\alpha }\left( i\right)\,{:=}\,1+\frac{1}{H_{\alpha }^{-1}\left(i\right) }, H_{\alpha}}$$\end{document} being the familiar fast growing Hardy function and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${H_{\alpha }^{-1}\left( i\right)\,{:=}\,\rm min \left\{ j \mid H_{\alpha } \left ( j\right) \geq i \right\}}$$\end{document} the corresponding slowly growing inversion. If \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\alpha < \varepsilon _{0}}$$\end{document}, then \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{SWP}\left({\rm S}\text{\textsc{eq}}^{2}, \trianglelefteq _{2}, 1_{\alpha}\right)}$$\end{document} is provable in T = PA. \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\sf{SWP}\left( {\rm S}\text{\textsc{eq}}^{2}, \trianglelefteq _{2},1_{\varepsilon _{0}}\right)}$$\end{document} is not provable in T = PA. We conjecture that this pattern is characteristic for all \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${T\supseteq \sf{PA}}$$\end{document} under consideration and their proof-theoretical ordinals o (T ), instead of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\varepsilon _{0}}$$\end{document}. (shrink)

In the real world, individual resources are crucial for patients when epidemics outbreak. Thus, the coupled dynamics of resource diffusion and epidemic spreading have been widely investigated when the recovery of diseases significantly depends on the resources from neighbors in static social networks. However, the social relationships of individuals are time-varying, which affects such coupled dynamics. For that, we propose a coupled resource-epidemic dynamic model on a time-varying multiplex network to synchronously simulate the resource diffusion and epidemic spreading in (...) dynamic social networks. The equilibrium analysis of the coupled model is conducted in a general scenario where the resource generation varies between susceptible and infected states and the recovery rate changes between resourceful and noresource states. By using the microscopic Markov chain approach and Monte Carlo simulations, we determine a probabilistic framework of the intralayer and interlayer dynamic processes of the coupled model and obtain the outbreak threshold of epidemic spreading. Meanwhile, the experimental results show the trivially asymmetric interactions between resource diffusion and epidemic spreading. They also indicate that the stronger activity heterogeneity and the larger contact capacity of individuals in the resource layer can more greatly promote resource diffusion, effectively suppressing epidemic spreading. However, these two individual characters in the epidemic layer can cause more resource depletion, which greatly promotes epidemic spreading. Furthermore, we also find that the contact capacity finitely impacts the coupled dynamics of resource diffusion and epidemic spreading. (shrink)

A number of recent studies have documented rapid changes in behavioural sensory acuity induced by aversive learning in the olfactory and auditory modalities. The effect of aversive learning on the discrimination of low-level features in the visual system of humans remains unclear. Here, we used a psychophysical staircase procedure to estimate discrimination thresholds for oriented grating stimuli, before and after differential aversive learning. We discovered that when a target grating orientation was conditioned with an aversive loud noise, it (...) subsequently led to an improvement of discrimination acuity in nearly all subjects. However, no such change was observed in a control group conditioned to an orientation shifted by ±90° from the target. Our findings cannot be explained by contextual learning or sensitisation factors. The results converge with those reported in the olfactory modality and provide further evidence that early sensory systems can be rapidly modified by recently experienced reinforcement histories. (shrink)

The recent discovery of a phenomenon of craniofacial growth, called craniofacial contraction, throws a new light on the process of hominization. The main interest of this discovery lies in a growth principle combining the different craniofacial units, that is to say, the neurocranium, the chondrocranium and the splanchnocranium. Until recent years, these different parts were considered as neighbouring element without any morphogenic or morphodynamic connection. But now, we know that the morphogenesis of the base of the skull governs that of (...) the face. This basicranial morphogenesis is the occipital flexion. It generates morphogenic correlations with the face since embryogenesis. The ontogenic pathway of this phenomenon is the craniofacial contraction. It concerns embryonic dynamics connected with the spatial development of the embryonic neural system, the neural tube. These morphodynamics are common to each primate species, but they are differenciated by the amplitude of the embryonic contraction. We ask ourself the question: is hominization of the neurocephalic embryogenesis, that is the craniofacial contraction, plausible over a very long period, with gradual and chaotic evolutionary pathways, or, on the contrary, is the complexity of such an embryonic phenomenon, a limiting factor generating determined and predictible ontogenic thresholds? The study of extant and fossil primate skulls demonstrates that species are organized around 6 levels of embryonic contraction, which, starting from 60 millions years, evolve from the less to the most contracted skull. Among each ontogenic level, living and fossil species develop from the same embryonic system but between both levels, the embryos suddenly are reorganized. Therefore, I have defined an evolutive ontogenic unity, that is the fundamental ontogenesia. The cephalic pole has a fundamental ontogenesis, meaning that, beyond the diversities, we can see the same contraction in many living and extinct species. The ontogenic diversities are the result of the microevolution and are not predictible. In such a perspective, the ontogenic morphodynamics evolve with chaotic trajectories. But, between two embryonic levels, or two fundamental ontogeneses, evolutionary modalities are different. Eventually, from 60 millions years to XXth century, we observe the same phenomenon than during human ontogenesis; hominization of the cephalic pole is a craniofacial contraction. The evolutive pathway is stable, whatever the number of thresholds, the cranial shape changes but the ontogenic trajectory is preserved. This is a macroevolution because the embryonic system is reorganized. The logics of the phenomenon are an increasing dynamization, the human ontogenesis is the more unstable and the longer morphodynamics to stabilize the craniofacial contraction. To conclude, hominization is an iteration of an ontogenic process when embryos reach successive dynamic thresholds. The attractors are neither static, periodic, nor chaotic because the successive ontogenic trajectories are themselves in a stable evolutive trajectory, and the results with increasing contraction, complexified neocortical tissues and cephalocaudal reorganization are predictible. During hominization, irreversibility and innovations do not emerge with chaotic determinism, but with harmonic determinism in association with the correlations established between the embryonic tissues. When the system is destabilized, the embryonic systems do not forget the previous ontogenic pattern, on the contrary, they develop the pattern with new dynamical conditions. This sort of phenomenon is not described in the sciences of complexity. In the present case, we are in front of many millions years and the necessity to propose new concepts such as a new familly of attractors, namely the harmonic attractors. (shrink)

This paper is about the statics and dynamics of belief states that are represented by pairs consisting of an agent's credences (represented by a subjective probability measure) and her categorical beliefs (represented by a set of possible worlds). Regarding the static side, we argue that the latter proposition should be coherent with respect to the probability measure and that its probability should reach a certain threshold value. On the dynamic side, we advocate Jeffrey conditionalisation as the principal mode of (...) changing one's belief state. This updating method fits the idea of the Lockean Thesis better than plain Bayesian conditionalisation, and it affords a flexible method for adding and withdrawing categorical beliefs. We show that it fails to satisfy the traditional principles of Inclusion and Preservation for belief revision and the principle of Recovery for belief withdrawals{, as well as the Levi and Harper identities. We take this to be a problem for the latter principles rather than for the idea of coherent belief change. (shrink)

This paper mainly analyzes the theories related to the financial risk of the company and combines the principles of principal component analysis, particle swarm optimization algorithm, and artificial neural network to derive the financial risk index system of the company. To improve the accuracy of financial risk prediction, principal component analysis and particle swarm algorithm are applied to optimize the BP neural network model, the input data of the prediction model is improved, and the optimal initial weights and thresholds (...) are given to the BP neural network by using particle swarm algorithm search, whereby the financial risk prediction model of particle swarm optimization BP neural network is constructed. The empirical results show that the model constructed by BP neural network not only has a high accuracy rate for static financial risk evaluation but also has a better prediction effect. After training and testing, the BP neural network-based enterprise financial risk evaluation model can accurately determine the existing financial situation of enterprise financial management and has a good prediction effect. Our research method is a fusion of the processing of the two methods, which belongs to the first integration of results. (shrink)

This paper is focused on the Sapient and Sentient Intelligence Value Argument or SSIVA and the ethics of how that applies to autonomous systems and how such systems might be governed by the extension of current regulation, as well as providing a computable model of ethics for AGI research. SSIVA is based on some static core definitions of "Intelligence" as defined by the measured ability to understand, use, and generate knowledge or information independently, all of which are a function (...) of sapience and sentience. The SSIVA logic places the value of any individual human and their potential for Intelligence, and the value of other systems to the degree that they are self-aware or "intelligent", as a priority. Further, the paper lays out the case for how the current legal framework could be extended to address issues with autonomous systems to varying degrees depending on the SSIVA threshold as applied to autonomous systems. Further, from a research standpoint it is important to have a descreet model to measure against without ambiguity, which the SSIVA theory provides. (shrink)

Previous research on the representation of nurses in literature has tended to rely on a ‘quasi‐scientific’ method that ultimately produces catalogues of static images. This paper argues that literary representations of nurses must be analysed in terms of situational context. In order to accomplish this die narratological concepts of the chronotope and the donor are used, resulting in a dynamic and powerful reading of nurses in narrative tales.

In lieu of an abstract, here is a brief excerpt of the content:Creating the Conditions for Intergenerational Justice: Social Capital and ComplianceAdelin-Costin DumitruIntroductionSuppose philosophers succeeded in putting forward two equally desirable theories of intergenerational justice. Both of them fare extremely well in regard to either a case-implication critique or a prior-principle strategy of argumentation (with the former requiring us to check the implications of a principle in counterfactual cases, and the latter testing the compatibility of a principle with certain more (...) fundamental values, according to Sen [197]). How are we to decide between them? To the extent that we believe that one of the purposes of political philosophy is to issue achievable and desirable recommendations (Stemplowska 319) or to be action-guiding (Swift 363), we might compare the two by applying a feasibility criterion. Such a criterion indicates that a state of affairs could be realized “if we were to summon sufficient practical will and direct our (individual or collective) efforts in the right direction” (Gheaus 450). In our case, the decision is a relatively easy one: both theories pass a threshold of acceptability and thus we would be morally justified in attempting to bring them about. Furthermore, by stipulation, world A in which theory x were implemented would be equally desirable as world B, in which theory y were implemented. The only distinction would be one concerning their feasibility.Nonetheless, this scenario is usually not one that is available to us. If theories differ based on their desirability as well as their feasibility, how are we to choose? One option would be to choose that moral theory which best satisfies the criteria mentioned by Buchanan, of moral accessibility, feasibility, and accessibility (Justice, Legitimacy). However, feasibility entails not only a static conception of duties, but a dynamic one, in which we postulate that agents have “duties that do not focus merely on what can be done in given [End Page 20] circumstances, but also on how to change circumstances so that new things can be done” (Gilabert and Lawford-Smith 812). In the present article, I argue that taking the idea of dynamic duties seriously requires that we redirect our efforts and resources toward those actions that would maximize the probability of achieving a successful transition from a non-ideal to an ideal state of the world. The argument is that, in the specific context of intergenerational justice, we ought to pay more attention to the matter of social capital extant in a society, if we want to achieve the ends of an intergenerational theory of justice. The concept of social capital puts under the same umbrella distinct features of social life such as networks and civic engagement, the role of reciprocity and trust in building institutions, and the effects that informal rules and institutions have on formal ones (Ostrom and Ahn, “Social Science Perspective” 4). Intuitively, these aspects are relevant for an account of intergenerational justice. The particular way in which they are relevant will be detailed later in this article.The claim that I defend is that the higher the level of social capital in a community, the more probable it will be that individuals are willing to redistribute resources to future generations. The underlying assumption that holds throughout the article is that public justification is important in construing a defense of a conception of justice. I proceed as follows. In the first section, I present an account of social capital. In the second section, I present the literature connecting social capital to political philosophy. In the third section, I argue why developing social capital is a worthwhile goal to pursue if we want to achieve intergenerational justice. The fourth section presents a series of measures that can increase the level of social capital. The fifth section responds to a series of potential objections that could be raised and concludes the paper.The Many Faces of Social CapitalMuch of the intellectual history of the twentieth century was dedicated to institutions and their function in shaping the social, economic, cultural, and political order. In a comprehensive definition put forward by March and Olsen, institutions represent “routines, procedures, conventions, roles, strategies, organizational forms, technologies..., beliefs, paradigms, codes, cultures and knowledge that surround, support, elaborate, and... (shrink)

Publication date: 16 April 2018 Source: Author: Parto Fazli, Ebrahim Abbasi The objective of the study is to test experimentally the Kuznets curve of energy intensity in selected developing countries with the focus of D-8 countries during 1990-2014. According to the results, and by using the static and dynamic estimators and the Panel- ARDL model, the Kuznets curve was accepted for energy intensity and the per capita income threshold was estimated $3931.25. The urbanization rate and the degree of industrialization (...) have a positive and significant effect on the GDP of consuming energy of D-8 countries in the long term. The most important policy recommendations were discussed for policy-makers and researchers. (shrink)

Limitarianism holds that there is an upper limit to how many resources, such as wealth and income, people can permissibly have. In this article, I examine the conceptual structure of limitarianism. I focus on the upper limit and the idea that resources above the limit are ‘excess resources’. I distinguish two possible limitarian views about such resources: (i) that excess resources have zero moral value for the holder; and (ii) that excess resources do have moral value for the holder but (...) that their claim to such resources is outweighed by other normative concerns. Moreover, I argue that, depending on the values limitarianism seeks to promote, limitarians should care about the number of people with excess resources or the total amount of excess resources (or both), that they can adopt redistributive measures and/or predistributive measures, and that some versions of limitarianism should take into account the distribution of risk among those above the riches line. (shrink)

Despite the prominence of thresholds in theories of distributive justice, there is no general account of what sort of role is played by the idea of a threshold within such theories. This has allowed an ongoing lack of clarity and misunderstanding around views that employ thresholds. In this article, I develop an account of the concept of thresholds in distributive justice. I argue that this concept contains three elements, which threshold views deploy when ranking possible distributions. These (...) elements are (i) the level of the threshold, (ii) what constitutes the value of the threshold, and (iii) how benefits above and below the threshold must be allocated. I highlight three contributions that this particular account of thresholds makes: it clarifies the nature of the shift that occurs at the threshold; it resolves a common misunderstanding about headcount principles; and it shows how the arbitrariness objection can be met. (shrink)

Pain is modulated by cognitive factors, including attention and emotions. In this study we evaluated the distractive effect of aesthetic appreciation on subjectively rated pain and multi-channel evoked potentials induced by CO2 laser stimulation of the left hand in twelve healthy volunteers. Subjects were stimulated by laser in the absence of other external stimulation and while looking at different paintings they had previously rated as beautiful, neutral or ugly. The view of paintings previously appreciated as beautiful produced lower pain scores (...) and a clear inhibition of the P2 wave amplitude, localized in the anterior cingulate cortex; the inhibition of P2 wave amplitude was lesser or not significant during the presentation of the ugly or neutral paintings, respectively. Dipole source localization analysis of the LEP peaks showed significant changes during different conditions, with a shift from the posterior to the anterior right cingulated cortex while looking at paintings previously rated as beautiful. (shrink)

In sensory biology, a major outstanding question is how sensory receptor cells minimize noise while maximizing signal to set the detection threshold. This optimization could be problematic because the origin of both the signals and the limiting noise in most sensory systems is believed to lie in stimulus transduction. Signal processing in receptor cells can improve the signal‐to‐noise ratio. However, neural circuits can further optimize the detection threshold by pooling signals from sensory receptor cells and processing them using a combination (...) of linear and nonlinear filtering mechanisms. In the visual system, noise limiting light detection has been assumed to arise from stimulus transduction in rod photoreceptors. In this context, the evolutionary optimization of the signal‐to‐noise ratio in the retina has proven critical in allowing visual sensitivity to approach the limits set by the quantal nature of light. Here, we discuss how noise in the mammalian retina is mitigated to allow for highly sensitive night vision. (shrink)

This article offers a detailed review of Filosofi italiani contemporanei, a book that presents overviews of seven contemporary Italian philosophers and philosopher/theologians—Luigi Pareyson, Emanuele Severino, Italo Mancini, Gianni Vattimo, Vincenzo Vitiello, Massimo Cacciari, and theologian Bruno Forte. Not intended as a comprehensive survey of the contemporary Italian philosophical scene, the book presents thinkers influential during the last three decades who have focused on tradition, post-metaphysical conceptions of being, origin, and principle, and the openness of philosophy to religion. Although eccentric by (...) Anglo-American standards, the selection does not misrepresent recent Italian philosophizing, which has been more thoroughgoingly shaped by neo-scholasticism, idealism, Nietzsche, Heidegger, and nihilism than most English-language work. Open to international philosophy as well as to its own traditions, Italian thinkers work within a complex ethos that has produced significant recent philosophizing and holds great promise for the future. (shrink)

_Threshold Concepts on the Edge_ explores new directions in threshold concept research and practice and is of relevance to teachers, learners, educational researchers and academic developers.

This essay represents a serious but fictional obituary of a scientific concept called the Threshold Dose–Response Model, which has long dominated the fields of toxicology and the broader biomedical sciences. Recent evidence indicates that the Threshold Dose–Response Model has long outlived its utility to predict low‐dose effects. In fact, so poorly does this model predict low‐dose responses that the idea arose that it should receive a symbolic burial recounting its achievements and failings, hence this obituary. BioEssays 29:686–688, 2007. © 2007 (...) Wiley Periodicals, Inc. (shrink)

A static, spherically symmetric, and asymptotically flat solution of coupled Einstein-Born-Infeld equations is presented. When the internal mass of the system is zero the resulting space-time is regular and describes static electromagnetic geon.

SummaryVisual acuity was tested and the anterior portion of the eye inspected among the Gidra in Lowland Papua New Guinea, who depend on hunting for their animal food. The visual acuity of the youths and adults was as high as that of hunters and gatherers; 88% of the males and 81% of the females had an acuity of 1·2 or better. The elders had far lower acuity, correlated with the advance of cataract. The senescent visual (...) class='Hi'>acuity is discussed in relation to little practice and low productivity of the elders' hunting, and to the Gidra traditional age-grade system. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)