Theory testing in experimental biology: the chemiosmotic mechanism of ATP synthesis

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (1):29-52 (2002)
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Abstract

Historians of biology have argued that much of the dynamics of experimental disciplines such as genetics or molecular biology can be understood from studying experimental systems and model organisms alone . Such accounts contrast sharply with more traditional philosophies of science which viewed scientific research essentially as a process of inventing and testing theories. I present a case from the history of biochemistry which can be viewed from both the experimental systems perspective and from the methodology of theory testing. I argue that not only are the two perspectives fully compatible, but they are both necessary for a complete account of the research process

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Marcel Weber
University of Geneva