Abstract

This chapter offers a framework for understanding significance that tolerates our incomplete knowledge of the conditions for human well-being. Topics discussed include the role of significance in Strategic Reliabilism, a reason-based approach to significance, and the potential unavailability of objective reasons. It is argued that a proper understanding of the notion of epistemic significance is a core problem for any epistemological theory that claims to be able to guide reason, and that any epistemological view that gives a central place to the notion of significance is bound to be deeply empirical.