Logic of discovery and justification in regulatory genetics

Studies in History and Philosophy of Science Part A 4 (4):349-385 (1974)
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Abstract

In the above pages I have sketched a history of the genesis and comparative evaluation of the repressor model of genetic regulation of enzyme induction. I have not attempted in this article to carry out an analysis of the more scientifically interesting fully developed Jacob-Monod operon theory of genetic regulations but such an analysis of the operon theory would not, I believe, involve any additional logical or epistemological features than have been discussed above. I have argued that the above account of the development of a theory of enzyme induction involved inferential moves and well-characterized desiderata, of both empirical and non-empirical character, in the genesis and evaluation of new hypotheses and theories. I have also contended that the reasoning displayed in the genesis of a theory is in a large measure identical to that utilized in evaluating a theory. Both of these conclusions are at variance with the views of philosophers such as H. Reichenbach, Sir Karl Popper, and C.G. Hempel who have argued that the genesis of new hypotheses is primarily an irrational affair and that only the context of justification is susceptible of rational reconstruction. In the alternative view presented here, scientific discovery and scientific justification represent the application in contexts, which are primarily telically distinguishable, of a fundamentally unitary logic of scientific inquiry

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Kenneth Schaffner
University of Pittsburgh

Citations of this work

Interfield theories.Lindley Darden & Nancy Maull - 1977 - Philosophy of Science 44 (1):43-64.
Strategies in the interfield discovery of the mechanism of protein synthesis.Lindley Darden & Carl Craver - 2002 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (1):1-28.
Scientific Reasoning Is Material Inference: Combining Confirmation, Discovery, and Explanation.Ingo Brigandt - 2010 - International Studies in the Philosophy of Science 24 (1):31-43.
Discovery and justification.Carl R. Kordig - 1978 - Philosophy of Science 45 (1):110-117.

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