Abstract
This paper describes in some detail a pattern of justification which seems to be part of common sense logic and also part of the logic of scientific investigations. Calling this pattern abduction, the paper lays out an abduction-prediction model of scientific inference as an update to the traditional hypothetico-deductive model. According to this newer model, scientific theories receive their claims for acceptance and belief from the abductive arguments that support them, and the processes of scientific discovery aim to develop theories with strong abductive support. It is suggested that the study of diagnosis presents a good opportunity for studying abduction under somewhat simpler and more reproducible conditions than occur in scientific discovery. A computer-based diagnostic system is described which provides a small-scale validation of the abduc-tion-prediction model by showing that a version of it can be made precise enough to be implemented and to perform correctly for diagnosis.