Abstract
Background: This systematic review explores a diverse range of international and indigenous healthcare research studies, spanning topics from diabetes management to cardiovascular care. The synthesis aims to identify overarching themes, sub-themes, and emerging trends in healthcare practices, emphasizing the integration of digital technologies and advancements in nutrition therapy. Aim: The primary objective is to provide a comprehensive overview of healthcare literature, combining international and indigenous perspectives, to uncover commonalities and distinctions in approaches to patient care, treatment modalities, and research methodologies. Method: A systematic and thorough review of 20 selected studies, encompassing international and Saudi Arabian research, was conducted. The studies, published between 2020 and 2024, were analyzed for their key themes, sub-themes, and trends, creating a detailed understanding of the current landscape of healthcare practices. Results: The synthesis revealed recurring themes, including the integration of digital technologies in diabetes care, advancements in medical nutrition therapy for obesity management, dynamic risk assessment in atrial fibrillation, and the potential of genetically modified food for nutritional security in Saudi Arabia. Sub-themes elucidated nuanced aspects of these overarching themes, offering a holistic perspective on contemporary healthcare strategies. Conclusion: International and indigenous research studies collectively underscore the importance of collaborative and context-specific approaches to healthcare. While global insights contribute to a broader understanding, indigenous studies emphasize the necessity of tailoring interventions to local needs. The synthesis not only highlights current achievements in healthcare but also identifies areas for further exploration and improvement.